Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Aileen, Boyle"'
Autor:
Aileen Boyle, Chris Plinston, Fraser Laing, Graeme Mackenzie, Robert G. Will, Jean C. Manson, Abigail B. Diack
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 6, Pp 1300-1303 (2020)
We investigated a clinical case of variant Creutzfeldt-Jakob Disease in a person heterozygous for methionine/valine at codon 129 of the prion protein gene and identified the same strain properties in variant Creutzfeldt-Jakob disease in methionine ho
Externí odkaz:
https://doaj.org/article/07853de152be4d9f8d89188e57599124
Autor:
Abigail B. Diack, Aileen Boyle, Diane Ritchie, Chris Plinston, Dorothy Kisielewski, Jesús de Pedro-Cuesta, Alberto Rábano, Robert G. Will, Jean C. Manson
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 9, Pp 1593-1596 (2017)
We investigated transmission characteristics of variant Creutzfeldt-Jakob disease in a mother and son from Spain. Despite differences in patient age and disease manifestations, we found the same strain properties in these patients as in UK vCJD cases
Externí odkaz:
https://doaj.org/article/b620a24940044c778625fd4f6dd6bdbf
Autor:
Abigail B. Diack, Diane Ritchie, Alexander H. Peden, Deborah Brown, Aileen Boyle, Laura Morabito, David Maclennan, Paul Burgoyne, Casper Jansen, Richard S. Knight, Pedro Piccardo, James W. Ironside, Jean C. Manson
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 12, Pp 1969-1979 (2014)
Variably protease-sensitive prionopathy (VPSPr) can occur in persons of all codon 129 genotypes in the human prion protein gene (PRNP) and is characterized by a unique biochemical profile when compared with other human prion diseases. We investigated
Externí odkaz:
https://doaj.org/article/34b55023ca104846b7b5d94b2b3c506a
Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes
Autor:
Abigail B. Diack, Emma Hunt, Matthew Bishop, Jean Manson, Christopher Plinston, Robert G. Will, Aileen Boyle
Publikováno v:
Diack, A, Boyle, A, Plinston, C, Hunt, E, Bishop, M, Will, R & Manson, J 2019, ' Variant Creutzfeldt-Jakob Disease strain is identical in individuals of two PRNP codon 129 genotypes ', Brain, vol. 142, no. 5, pp. 1416-1428 . https://doi.org/10.1093/brain/awz076
Brain
Brain
The methionine/valine (M/V) SNP at codon 129 of the prion protein gene PRNP influences susceptibility to prion diseases. Diack et al. report that vCJD strain properties are not affected by transmission through an individual with the PRNP MV codon 129
Autor:
Jean Manson, Aileen Boyle, Abigail B. Diack, Christopher Plinston, Graeme Mackenzie, Fraser Laing, Robert G. Will
Publikováno v:
Boyle, A, Plinston, C, Laing, F, Mackenzie, G, Will, R G, Manson, J & Diack, A 2020, ' No adaption of the prion strain in a heterozygous case of variant Creutzfeldt-Jakob disease ', Emerging Infectious Diseases, vol. 26, no. 6, pp. 1300-1303 . https://doi.org/10.3201/eid2606.191116
Emerging Infectious Diseases, Vol 26, Iss 6, Pp 1300-1303 (2020)
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 26, Iss 6, Pp 1300-1303 (2020)
Emerging Infectious Diseases
In 2016, the first definite case of clinical variant Creutzfeldt-Jakob disease (vCJD) in a 129MV individual was reported in the United Kingdom (1). The clinical features were consistent with either sporadic CJD (sCJD) or vCJD and brain magnetic reson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a82a66ececd6f03cb95ba2f8f6a909
https://www.pure.ed.ac.uk/ws/files/148847366/19_1116.pdf
https://www.pure.ed.ac.uk/ws/files/148847366/19_1116.pdf
Autor:
Romolo Nonno, Michele A Di Bari, Franco Cardone, Gabriele Vaccari, Paola Fazzi, Giacomo Dell'Omo, Claudia Cartoni, Loredana Ingrosso, Aileen Boyle, Roberta Galeno, Marco Sbriccoli, Hans-Peter Lipp, Moira Bruce, Maurizio Pocchiari, Umberto Agrimi
Publikováno v:
PLoS Pathogens, Vol 2, Iss 2, p e12 (2006)
Transmission of prions between species is limited by the "species barrier," which hampers a full characterization of human prion strains in the mouse model. We report that the efficiency of primary transmission of prions from Creutzfeldt-Jakob diseas
Externí odkaz:
https://doaj.org/article/545a1b1acbf7493ab3bccb4b17b37ca0
Autor:
Abigail B. Diack, John K. Fazakerley, Tom C. Freeman, James Vincenti, Aileen Boyle, Dorothy Kisielewski, Jean Manson, Lita Murphy, V. Hugh Perry, James Alibhai, Pedro Piccardo, Rennos Fragkoudis
Publikováno v:
Prion. 9:S1-S10
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1658
Transmissible spongiform encephalopathies (TSE) or prion diseases exhibit strain variation, a phenomenon that has been studied extensively in mouse bioassays. Despite the introduction of many rapid in vitro systems, bioassays remain a key tool in def
Publikováno v:
Prions ISBN: 9781493972425
Transmissible spongiform encephalopathies (TSE) or prion diseases exhibit strain variation, a phenomenon that has been studied extensively in mouse bioassays. Despite the introduction of many rapid in vitro systems, bioassays remain a key tool in def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b48d6caa1fe8eac99afb5f23708d36b9
https://doi.org/10.1007/978-1-4939-7244-9_18
https://doi.org/10.1007/978-1-4939-7244-9_18
Autor:
Aileen Boyle, Mark Head, Sandra McCutcheon, James W. Ironside, Robert G. Will, Jean Manson, Richard Knight, Abigail B. Diack
Publikováno v:
Diack, A B, Head, M W, McCutcheon, S, Boyle, A, Knight, R, Ironside, J W, Manson, J C & Will, R G 2014, ' Variant CJD : 18 years of research and surveillance ', Prion, vol. 8, no. 4, pp. 286-295 . https://doi.org/10.4161/pri.29237
It is now 18 years since the first identification of a case of vCJD in the UK. Since that time there has been much speculation over how vCJD might impact on human health. To date there have been 177 cases reports in the UK and a further 51 cases worl