Výsledky vyhledávání - "Aiko Yamane-Sugiyama"

The Anti-inflammatory Effect of FR188582, a Highly Selective Inhibitor of Cyclooxygenase-2, With an Ulcerogenic Sparing Effect in Rats

Autor: Yoshitaka Ohkubo, Hirokazu Tanaka, Kazuo Sakane, Aiko Yamane-Sugiyama, Takehiro Ochi

Publikováno v: Japanese Journal of Pharmacology. 85:175-182

The anti-inflammatory and ulcerogenic effects of FR188582, 3-chloro-5-[4-(methylsulfonyl) phenyl]-1-phenyl-1H-pyrazole, were investigated. In a recombinant human cyclooxygenase (COX) enzyme activity, FR188582 inhibited COX-2 with an IC50 value of 0.0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46b7ffd15781ec3450a69914004c6ce
https://doi.org/10.1254/jjp.85.175

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