Výsledky vyhledávání

Molecular analysis of antigenicity and immunogenicity of a vaccine-induced escape mutant of hepatitis B virus

Autor: Riho Joh, Aiko Iizuka, Takuma Naritomi, Naoko Kanai, Kayo Ishikawa, Miho Ogawa, Toru Shizuma, Nobuyuki Torii, Kiyoshi Hasegawa, Naoaki Hayashi

Publikováno v: Journal of Gastroenterology. 38:244-253

To analyze the mechanisms of mutant escape, we established a murine model of hepatitis B virus (HBV) infection and studied the interaction of the envelope protein of the virion with various kinds of anti-hepatitis B antibody. Methods: Mutation from g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35196c12e634549224abfeb720d80eb3
https://doi.org/10.1007/s005350300043

Zobrazit plný text záznamu

Different antibody responses against hepatitis B surface antigen among mouse strains transfected with mutant viral DNA

Autor: Naoko Kanai, Miho Ogawa, Naoaki Hayashi, Riho Joh, Aiko Iizuka, Kiyoshi Hasegawa, Nobuyuki Torii, Takuma Naritomi

Publikováno v: Journal of Gastroenterology. 37:1035-1041

Rapid seroconversion from hepatitis B surface antigen (HBsAg) to anti-HBs antibody is seen in most patients with fulminant hepatitis B. It is unclear whether viral mutation or host immune background is responsible for such enhanced host reaction to h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3c81e17ccd97b7974e0175490ee333
https://doi.org/10.1007/s005350200174

Zobrazit plný text záznamu

Repeated Jaundice due to YMDD Mutant in a Patient with Prolonged Lamivudine Therapy for Chronic Hepatitis B under Prednisolone Treatment for Still's Disease

Autor: Takuma Naritomi, Kayo Ishikawa, Nobuyuki Torii, Naoko Kanai, Miho Ogawa, Etsuko Hashimoto, Aiko Iizuka, Naoaki Hayashi, Kiyoshi Hasegawa, Toru Shizuma, Riho Joh

Publikováno v: Internal Medicine. 41:701-705

A 50-year-old woman patient began receiving lamivudine because of acute exacerbation of chronic hepatitis B. She also suffered from adult-onset Still's disease and had received prednisolone for 5 years. Lamivudine was effective for treatment of the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cedc1c08b03f6ea4a604a318d0a1618
https://doi.org/10.2169/internalmedicine.41.701

Zobrazit plný text záznamu

Genotypic analysis of hepatitis B virus from patients with fulminant hepatitis: comparison with acute self-limited hepatitis

Autor: Takuma Naritomi, Aiko Iizuka, Nobuyuki Torii, Etsuko Hashimoto, Naoko Kanai, Miho Ogawa, Kiyoshi Hasegawa, Riho Joh, Naoaki Hayashi, Kayo Ishikawa

Publikováno v: Hepatology research : the official journal of the Japan Society of Hepatology. 26(2)

AIM/BACKGROUND: There is an increasing evidence that certain hepatitis B virus (HBV) strains may contribute to the pathogenesis of fulminant hepatitis B (FHB). Recently, we reported that genotypes of HBV influence the clinical course of acute self-li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f0475554f696ee9943d7129f090d90
https://pubmed.ncbi.nlm.nih.gov/12809939

Zobrazit plný text záznamu