Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aiko Iida"'
Autor:
Toshio Oda, Jun Aketagawa, Yasuhiko Ito, Shohei Ouchi, Mikio Tomita, Yusuke Takizawa, Masahiro Hayashi, Aiko Iida
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 43(6)
The Editor-in-Chief has retracted this article [1] based on an investigation by the Ministry of Education, Culture, Sports, Science and Technology, Japan, which found that the article contained overlap with a previously published article by Kalitsky-
Autor:
Mikio Tomita, Yusuke Takizawa, Yasuhiko Ito, Aiko Iida, Toshio Oda, Jun Aketagawa, Masahiro Hayashi, Shohei Ouchi
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 40:29-38
Infection and inflammation suppress the expression and activity of several drug transporters in liver. In the intestine, P-glycoprotein (P-gp/MDR1), multidrug resistance-associated protein 2 (MRP2), and breast cancer resistance protein (BCRP) are imp
Publikováno v:
Drug Metabolism and Pharmacokinetics. 20:100-106
It has been reported that inhibition of the P-glycoprotein (P-gp) results in the improved absorption of P-gp substrate in the intestinal tract. In fact, the increased permeability of P-gp substrate across the intestinal epithelium was observed follow
Publikováno v:
Experimental and Molecular Pathology. 69:119-143
In an attempt to improve liver slice culture for in vitro tests of newly developed drugs, we found that a relatively thick 2-mm slice was much more viable, long-lived, and metabolically functional than the conventionally used 300-μm-thick slices. Re
Autor:
Aiko, Iida, Shohei, Ouchi, Toshio, Oda, Jun, Aketagawa, Yasuhiko, Ito, Yusuke, Takizawa, Mikio, Tomita, Masahiro, Hayashi
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 40(1)
Infection and inflammation suppress the expression and activity of several drug transporters in liver. In the intestine, P-glycoprotein (P-gp/MDR1), multidrug resistance-associated protein 2 (MRP2), and breast cancer resistance protein (BCRP) are imp
Publikováno v:
Drug metabolism and pharmacokinetics. 21(5)
The purpose of the present experiment was to examine the effects of D-tartaric acid (TA) on intestinal drug absorption under both in situ and in vitro experimental conditions. In the in vitro diffusion chamber experiments, TA (10 mM) added to the muc
Autor:
T Nishikawahara, Y Hasegawa, Hideki Tomioka, Aiko Iida, Shoji Awazu, Masahiro Hayashi, N Shimizu, Takaaki Sakai, Mikio Tomita
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 62(1-2)
We examined the action mechanisms of enhancers that improve paracellular drug transport. For sodium caprate (C10), the increase in the intracellular calcium level was considered to induce the contraction of calmodulin-dependent actin filaments, follo
Autor:
Masahiro Hayashi, Yasuhiro Hasegawa, Aiko Iida, Hideki Tomioka, Naoaki Shimizu, Mikio Tomita, Shoji Awazu, Toshiro Sakai
Publikováno v:
Drug Metabolism and Pharmacokinetics. 12:84-85