Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Aiko I. Klingler"'
Autor:
Bao-Feng Wang, Ping-Ping Cao, James E. Norton, Julie A. Poposki, Aiko I. Klingler, Lydia A. Suh, Roderick Carter, Julia H. Huang, Junqin Bai, Whitney W. Stevens, Bruce K. Tan, Anju T. Peters, Leslie C. Grammer, David B. Conley, Kevin C. Welch, Zheng Liu, Robert C. Kern, Atsushi Kato, Robert P. Schleimer
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:1379-1390.e11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d504b3654f23ad8cb72e669ea028ed2
https://doi.org/10.1016/j.jaci.2022.11.029
https://doi.org/10.1016/j.jaci.2022.11.029
Autor:
David B. Conley, Leslie C. Grammer, Anju T. Peters, Joseph R. Raviv, Pejman Soroosh, Kathryn E. Hulse, Stephanie Shintani Smith, Whitney W. Stevens, Kenichi Takano, Tetsuo Himi, Robert C. Kern, Julie A. Poposki, Noriko Ogasawara, Bruce K. Tan, Robert P. Schleimer, Aiko I. Klingler, Kevin C. Welch, Atsushi Kato
Publikováno v:
Mucosal immunology
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by type 2 inflammation with accumulation of activated group 2 innate lymphoid cells (ILC2s) and elevation of thymic stromal lymphopoietin (TSLP). A member of the TNF superfamily (TNFS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5112f3330a1007f6cba6ec3c0b0c0ad0
https://doi.org/10.1038/s41385-019-0215-8
https://doi.org/10.1038/s41385-019-0215-8
Autor:
Julie A. Poposki, Aiko I. Klingler, Whitney W. Stevens, Lydia A. Suh, Bruce K. Tan, Anju T. Peters, Hiam Abdala-Valencia, Leslie C. Grammer, Kevin C. Welch, Stephanie S. Smith, David B. Conley, Robert C. Kern, Robert P. Schleimer, Atsushi Kato
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is well characterized by type 2 (T2) inflammation characterized by eosinophilia in Western countries. However, the presence and the roles of neutrophils in T2 CRSwNP are poorly under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c63f8f1ff261e2dd5d78edf375c42e0
https://europepmc.org/articles/PMC9081139/
https://europepmc.org/articles/PMC9081139/
Autor:
Kevin C. Welch, Robert C. Kern, Robert P. Schleimer, Anju T. Peters, Atsushi Kato, David B. Conley, Leslie C. Grammer, Whitney W. Stevens, Aiko I. Klingler, Julie A. Poposki, Bruce K. Tan, Stephanie Shintani Smith
Publikováno v:
J Allergy Clin Immunol
Background Chronic rhinosinusitis (CRS) without nasal polyps (CRSsNP) is a common disease that is characterized by multiple inflammatory endotypes. However, the molecular mechanisms in CRSsNP are poorly understood compared with those of polypoid CRS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0299db62069b79e03171b94212218c9
https://pubmed.ncbi.nlm.nih.gov/33326802
https://pubmed.ncbi.nlm.nih.gov/33326802
Autor:
Leslie C. Grammer, Bruce K. Tan, Robert P. Schleimer, Noriko Ogasawara, Kathryn E. Hulse, Whitney W. Stevens, Aiko I. Klingler, Robert C. Kern, Stephanie Shintani Smith, Anju T. Peters, Atsushi Kato, David B. Conley, Julie A. Poposki, Kevin C. Welch
Publikováno v:
Allergy. 73:2251-2254
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54414ab5c37f63d257984afff29b297d
https://doi.org/10.1111/all.13552
https://doi.org/10.1111/all.13552
Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps
Autor:
Kevin C. Welch, Kathryn E. Hulse, Robert C. Kern, Julie A. Poposki, Homayon Banie, Pejman Soroosh, James G. Karras, Anju T. Peters, Stephanie Shintani Smith, Leslie C. Grammer, Joseph R. Raviv, David B. Conley, Whitney W. Stevens, Atsushi Kato, Aiko I. Klingler, Omid Akbari, Bruce K. Tan, Robert P. Schleimer, Gavin Lewis
Publikováno v:
Immunity, Inflammation and Disease. 5:233-243
Background Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines. Although T helper cytokines are released from T cells, innate lymphoid cells (ILC) are also known to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12fd3acaee26da21ce93c8fa1fb1f479
https://doi.org/10.1002/iid3.161
https://doi.org/10.1002/iid3.161
Autor:
Robert C. Kern, Kenichi Takano, Bruce K. Tan, Julie A. Poposki, Kathryn E. Hulse, Robert P. Schleimer, Stephanie Shintani Smith, Leslie C. Grammer, Tetsuo Himi, David B. Conley, Anju T. Peters, Kevin C. Welch, Noriko Ogasawara, Whitney W. Stevens, Aiko I. Klingler, Atsushi Kato
Publikováno v:
J Allergy Clin Immunol
TNF receptor II is expressed on ILC2s and TNF is able to induce production of type 2 cytokines in human ILC2s. TNF may play a role in causing or amplifying type 2 immunity contributing to health and disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b7896f102adcf5ada22466b0439171
https://pubmed.ncbi.nlm.nih.gov/31526804
https://pubmed.ncbi.nlm.nih.gov/31526804
Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps
Autor:
Julie A, Poposki, Aiko I, Klingler, Bruce K, Tan, Pejman, Soroosh, Homayon, Banie, Gavin, Lewis, Kathryn E, Hulse, Whitney W, Stevens, Anju T, Peters, Leslie C, Grammer, Robert P, Schleimer, Kevin C, Welch, Stephanie S, Smith, David B, Conley, Joseph R, Raviv, James G, Karras, Omid, Akbari, Robert C, Kern, Atsushi, Kato
Publikováno v:
Immunity, Inflammation and Disease
Background Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines. Although T helper cytokines are released from T cells, innate lymphoid cells (ILC) are also known to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cb50bfd3c30a2737db6a8e519c126c4
https://pubmed.ncbi.nlm.nih.gov/28474861
https://pubmed.ncbi.nlm.nih.gov/28474861
Autor:
Atsushi Kato, Noriko Ogasawara, Julie A. Poposki, Aiko I. Klingler, Kathryn E. Hulse, Bruce K. Tan, Whitney W. Stevens, Anju T. Peters, Leslie C. Grammer, Kevin C. Welch, Stephanie S. Smith, David B. Conley, Robert C. Kern, Robert P. Schleimer
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:AB1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4af144ddf92ac7bcdc735a2a5d46f3c7
https://doi.org/10.1016/j.jaci.2018.12.004
https://doi.org/10.1016/j.jaci.2018.12.004
Autor:
Bruce K. Tan, Robert P. Schleimer, Kathryn E. Hulse, David B. Conley, Atsushi Kato, Lydia Suh, Julie A. Poposki, Roderick G. Carter, Leslie C. Grammer, Kevin C. Welch, Aiko I. Klingler, Kathleen E. Harris, Anju T. Peters, Stephanie Shintani Smith, Whitney W. Stevens, James E. Norton, Robert C. Kern
CRSsNP is a heterogenous disease but type 2 inflammation in CRSsNP was more common than type 1 inflammation among patients in Chicago, Illinois. Distinct therapeutic strategies may be needed depending on the type of inflammation found in CRSsNP.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941b61f96bfed8abaf2e1ddc25288781
https://europepmc.org/articles/PMC5303134/
https://europepmc.org/articles/PMC5303134/