Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Aike A Kruize"'
Autor:
Cornelis P J Bekker, Maarten R Hillen, Sofie L M Blokland, Aike A Kruize, Joel AG van Roon, Timothy RDJ Radstake, Cornelia G van Helden-Meeuwsen, Marjan A Versnel, Helen L Leavis, Safae Hamkour, Ana P Lopes, Eefje HM van der Heijden
Publikováno v:
RMD Open, Vol 9, Iss 3 (2023)
Objectives To assess to what extent leflunomide (LEF) and hydroxychloroquine (HCQ) therapy in patients with primary Sjögren’s syndrome (RepurpSS-I) targets type I IFN-associated responses and to study the potential of several interferon associated
Externí odkaz:
https://doaj.org/article/b2355b45dacc41cd96ffe4289a16288d
Autor:
Timothy R D J Radstake, Joel A G van Roon, Maarten R Hillen, Sofie L M Blokland, Aike A Kruize, Fréderique M van Vliet-Moret, Angela Bikker, Wilco de Jager, Aridaman Pandit
Publikováno v:
RMD Open, Vol 5, Iss 1 (2019)
Objective To explore the potential of salivary gland biopsy supernatants (the secretome) as a novel tool to aid in stratification of patients with sicca syndrome and to study local immunopathology in Sjögren’s syndrome.Methods Labial salivary glan
Externí odkaz:
https://doaj.org/article/539dc20a783e49bdbfa5902bff2301dc
Autor:
Ana P Lopes, Maarten R Hillen, Eleni Chouri, Sofie L M Blokland, Cornelis P J Bekker, Aike A Kruize, Marzia Rossato, Joel A G van Roon, Timothy R D J Radstake
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193157 (2018)
Considering the important role of miRNAs in the regulation of post-transcriptional expression of target genes, we investigated circulating small non-coding RNAs (snc)RNA levels in patients with primary Sjögren's syndrome (pSS). In addition we assess
Externí odkaz:
https://doaj.org/article/3bf95586dc264d0e9a822452184e69d5
Autor:
Angela Bikker, Aike A Kruize, Kim M G van der Wurff-Jacobs, Rogier P Peters, Marije Kleinjan, Frank Redegeld, Wilco de Jager, Floris P J G Lafeber, Joël A G van Roon
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94756 (2014)
OBJECTIVES: To investigate the potential synergy of IL-7-driven T cell-dependent and TLR7-mediated B cell activation and to assess the additive effects of monocyte/macrophages in this respect. METHODS: Isolated CD19 B cells and CD4 T cells from healt
Externí odkaz:
https://doaj.org/article/dd0a25abc89840608da63f920b469656
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionMucosal-associated invariant T (MAIT) cells might play a role in B cell hyperactivity and local inflammation in primary Sjögren’s syndrome (pSS), just like previously studied mucosa-associated CCR9+ and CXCR5+ T helper cells. Here, we
Externí odkaz:
https://doaj.org/article/8937f8207a854d288f39f6a3bbedfb78
Autor:
Anneline C. Hinrichs, Sofie L. M. Blokland, Aike A. Kruize, Floris P. J. Lafeber, Helen L. Leavis, Joel A. G. van Roon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionIncreased CCL5 expression and CD8 T cells have been shown to be pivotal regulators of immunopathology in primary Sjögren’s syndrome (pSS) and pSS-like disease. Increased CCL5 expression by CCR9+ CD4 T cells has previously been implicat
Externí odkaz:
https://doaj.org/article/72a6a876f5d248908f8f6663bcfcea3a
Autor:
Ana P. Lopes, Cornelis P. J. Bekker, Maarten R. Hillen, Sofie L. M. Blokland, Anneline C. Hinrichs, Aridaman Pandit, Aike A. Kruize, Timothy R. D. J. Radstake, Joel A. G. van Roon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by infiltration of the exocrine glands and prominent B cell hyperactivity. Considering the key role of monocytes in promoting B cell hyperactivity, we performed RNA-se
Externí odkaz:
https://doaj.org/article/a9722ea29bae488390f401c8092783ed
Autor:
Anneline C. Hinrichs, Sofie L. M. Blokland, Ana P. Lopes, Catharina G. K. Wichers, Aike A. Kruize, Aridaman Pandit, Timothy R. D. J. Radstake, Joel A. G. van Roon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionCCR9+ Tfh-like pathogenic T helper (Th) cells are elevated in patients with primary Sjögren’s syndrome (pSS) and indicated to play a role in pSS immunopathology. Here we delineate the CCR9+ Th cell-specific transcriptome to study the m
Externí odkaz:
https://doaj.org/article/2ee682a5fca5423b96e9810c5dd65a8c
Autor:
Ana P Lopes, Maarten R Hillen, Anneline C Hinrichs, Sofie LM Blokland, Cornelis PJ Bekker, Aridaman Pandit, Aike A Kruize, Timothy RDJ Radstake, Joel A van Roon
Publikováno v:
Annals of the Rheumatic Diseases. 82:374-383
ObjectiveType 2 conventional dendritic cells (cDC2s) are key orchestrators of inflammatory responses, linking innate and adaptative immunity. Here we explored the regulation of immunological pathways in cDC2s from patients with primary Sjögren’s s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e670d596b7b5668c635bf623e23d803d
https://doi.org/10.1136/ard-2022-222728
https://doi.org/10.1136/ard-2022-222728
Autor:
Marie Wahren-Herlenius, Xavier Mariette, Jacques-Eric Gottenberg, Manuel Ramos-Casals, Chiara Baldini, Aike A. Kruize, Bei Xu, Virginia Fernandes Moça Trevisani, Gabriela Hernández-Molina, Jorge Sanchez-Guerrero, Pilar Brito-Zerón, Sung-Hwan Park, Sandra Gofinet Pasoto, Valeria Valim, Roberto Giacomelli, Roberta Priori, Kathy L. Sivils, Maureen Rischmueller, Wan-Fai Ng, Margit Zeher, Damien Sène, Berkan Armagan, Yasunori Suzuki, Valérie Devauchelle-Pensec, Marika Kvarnström, Soledad Retamozo, Guadalupe Fraile, Gunnel Nordmark, Sonja Praprotnik, Luca Quartuccio, Jacques Morel, Piotr Wiland, David A. Isenberg, Astrid Rasmussen, Seung-Ki Kwok, Stefano Bombardieri, Salvatore De Vita, Hendrika Bootsma, Benedikt Hofauer, Tamer A. Gheita, Thomas Mandl, Fabiola Atzeni, Xiaomei Li, Michele Bombardieri, Daniel Hammenfors, Antonina Minniti, Nihan Acar-Denizli, Roberto Gerli, Roser Solans, Levent Kilic, Eefje van der Heijden, Pulukool Sandhya, Hideki Nakamura, Raphaèle Seror, Debashish Danda, Ildikó Horváth, C. Vollenweider
Publikováno v:
Rheumatology
Rheumatology, Oxford University Press (OUP), 2019, ⟨10.1093/rheumatology/kez578⟩
Rheumatology, 59(9), 2350-2359. Oxford University Press
Rheumatology, 2019, ⟨10.1093/rheumatology/kez578⟩
Rheumatology, Oxford University Press (OUP), 2019, ⟨10.1093/rheumatology/kez578⟩
Rheumatology, 59(9), 2350-2359. Oxford University Press
Rheumatology, 2019, ⟨10.1093/rheumatology/kez578⟩
Objective To characterize the systemic phenotype of primary Sjögren’s syndrome at diagnosis by analysing the EULAR-SS disease activity index (ESSDAI) scores. Methods The Sjögren Big Data Consortium is an international, multicentre registry based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9000c0be743ba0f5386ddc3344f0eb
https://doi.org/10.1093/rheumatology/kez578
https://doi.org/10.1093/rheumatology/kez578