Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Aiji Sakamoto"'
Autor:
Aiji Sakamoto, Masaaki Kawashiri, Hatsue Ishibashi-Ueda, Yuka Sugamoto, Tsuyoshi Yoshimuta, Takeo Higashikata, Hitoshi Ogino, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, Masakazu Yamagishi
Publikováno v:
International Journal of Vascular Medicine, Vol 2012 (2012)
We examined the expression of ephrin-B1 and its cognate receptor EphB2, key regulators of angiogenesis and embryogenesis, in human abdominal aortic aneurysm (AAA) and analyzed their functional roles in cell migration. From 10 patients (9 males and 1
Externí odkaz:
https://doaj.org/article/e59eb1f5a77947c8a480c2f138733651
Autor:
Aiji Sakamoto, Tomohisa Hirobe
Publikováno v:
Journal of Dermatological Science. 110:72-75
Autor:
Yoshio Ijiri, Ryuji Kato, Yasukatsu Izumi, Tetsuya Hayashi, Sayuri Nagai, Takehiro Yamaguchi, Yuki Yasuda, Aiji Sakamoto, Yoko Sen, Yoshikatsu Okada, Kazuhiko Tanaka, Koyuha Amatani, Minoru Yoshiyama, Atsuo Nomura
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 307:H1626-H1633
The prevalence of sleep apnea is very high in patients with heart failure (HF). The aims of this study were to investigate the influence of intermittent hypoxia (IH) on the failing heart and to evaluate the antioxidant effect of hydrogen gas. Normal
Autor:
Aiji Sakamoto, Hatsue Ishibashi-Ueda, Takeo Higashikata, Susumu Miyamoto, Izumi Nagata, Koji Iihara, Noritoshi Nagaya, Hitonobu Tomoike, Takashi Iwase, Toshio Higashi, Masakazu Yamagishi
Publikováno v:
Atherosclerosis. 185:165-172
The balance between degradation and synthesis of extracellular matrix determines its content in atherosclerotic tissue. To examine the role of expression balance of matrix metalloproteinases (MMPs) to their inhibitors, tissue inhibitors of metallopro
Autor:
Aiji Sakamoto, Makoto Itoh, Kunio Miyatake, Junsho Shigeyama, Yoshio Ishida, Masafumi Kitakaze, Yoshio Yasumura, Tatsuya Fukutomi
Publikováno v:
European Heart Journal. 26:2698-2705
AIMS To elucidate the cellular mechanisms of cardioprotection of beta-blockers in patients with heart failure, we investigated the effects of beta-blockers on collagen synthesis in patients with dilated cardiomyopathy (DCM). METHODS AND RESULTS We ex
Publikováno v:
American Journal of Physiology-Renal Physiology. 288:F732-F739
Endothelin-1 (ET-1) increases the activity of Na+/H+exchanger 3 (NHE3), the major proximal tubule apical membrane Na+/H+antiporter. This effect is seen in opossum kidney (OKP) cells expressing the endothelin-B (ETB) and not in cells expressing the en
Autor:
Kenji Minatoya, Hatsue Ishibashi-Ueda, Aiji Sakamoto, Noritoshi Nagaya, Hiroyuki Hao, Hiroaki Sasaki, Masakazu Yamagishi, Hitonobu Tomoike, Takeo Higashikata, Hitoshi Ogino
Publikováno v:
Atherosclerosis. 177:353-360
The relative expression levels of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), key regulators in remodeling of extracellular matrix, are considered to play a pivotal role in the development of abdominal aortic
Autor:
Aiji Sakamoto
Publikováno v:
Molecular and Cellular Biochemistry. 259:183-187
Cardiomyopathy is primary degenerative disease of myocardium, which leads to cardiac failure and lethal arrhythmia. An appropriate model animal of a particular disease is, in general, greatly helpful for better understanding of its pathogenesis. In 1
Publikováno v:
Journal of Cardiac Failure. 9:469-474
The left ventricular functional recovery by beta-blocker therapy is now attributed to time-dependent biologic effects on cardiomyocytes.To elucidate the cellular mechanism of these biologic effects, we treated 9 patients with dilated cardiomyopathy f
Publikováno v:
Molecular and Cellular Biochemistry. 190:153-156
Endothelin receptor is a good model for analysis of the function of heptahelical G-protein coupled receptor. In ligand binding to the heptahelical receptor, the receptor has two functions, i.e. ‘message’ and ‘address’ functions. Each function