Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Aihao Ding"'
Autor:
Szu-Yi Chou, Kuo-Shun Hsu, Wataru Otsu, Ya-Chu Hsu, Yun-Cin Luo, Celine Yeh, Syed S. Shehab, Jie Chen, Vincent Shieh, Guo-an He, Michael B. Marean, Diane Felsen, Aihao Ding, Dix P. Poppas, Jen-Zen Chuang, Ching-Hwa Sung
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Chloride intracellular channel (CLIC) 4 is an ion channel, localized in the cytoplasm, and first identified as an actin binding protein. Here, Chou et al.knockout CLIC4 in mice and observe tubulogenesis and renal proximal tubule dilation defects, whi
Externí odkaz:
https://doaj.org/article/79963ebc449a4f9688cf9e04a58cb412
Autor:
Jay Kearney, Andrew G. Bowie, Stefan A. Schattgen, Michael Carty, Katherine A. Fitzgerald, Claudia Gürtler, Aihao Ding
Publikováno v:
The Journal of Immunology. 192:4821-4832
The four Toll/IL-1R domain–containing adaptor proteins MyD88, MAL, TRIF, and TRAM are well established as essential mediators of TLR signaling and gene induction following microbial detection. In contrast, the function of the fifth, most evolutiona
Autor:
Dongxu Sun1, Aihao Ding1 ahding@med.cornell.edu
Publikováno v:
Nature Immunology. Apr2006, Vol. 7 Issue 4, p375-381. 7p. 5 Graphs.
Autor:
Aihao Ding1,2 ahding@med.cornell.edu, Hongwei Yu1, Jingxuan Yang1, Shuangping Shi1,2, Ehrt, Sabine1,2 sae2004@med.cornell.edu
Publikováno v:
Immunology. Nov2005, Vol. 116 Issue 3, p381-389. 9p. 5 Diagrams, 2 Graphs.
Autor:
Bobby Thomas, Aihao Ding, Melissa B. Uccellini, Carl Nathan, Adolfo García-Sastre, Rebecca Banerjee, Ying-Ju Hou
Publikováno v:
The Journal of Immunology. 191:875-883
Four of the five members of the Toll/IL-1R domain–containing adaptor family are required for signaling downstream of TLRs, promoting innate immune responses against different pathogens. However, the role of the fifth member of this family, sterile
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(8)
Progranulin (PGRN) is a widely expressed, pleiotropic protein that is involved in diverse biological processes, including cellular proliferation, neuron development, and wound healing. However, the role of PGRN in the regulation of pathogen-induced s
Autor:
Guo An He, Celine Yeh, Wataru Otsu, Yun Cin Luo, Kuo-Shun Hsu, Syed S. Shehab, Aihao Ding, Diane Felsen, Jen-Zen Chuang, Dix P. Poppas, Ya Chu Hsu, Ching-Hwa Sung, Szu Yi Chou, Jie Chen, Michael B. Marean, Vincent Shieh
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Chloride intracellular channel 4 (CLIC4) is a mammalian homologue of EXC-4 whose mutation is associated with cystic excretory canals in nematodes. Here we show that CLIC4-null mouse embryos exhibit impaired renal tubulogenesis. In both developing and
Autor:
Chingwen Yang, Ching-Hwa Sung, Aihao Ding, Guoan He, Szu Yi Chou, Yao Ma, Jen-Zen Chuang, Huihong Li
Publikováno v:
European Journal of Immunology. 41:1221-1230
Chloride intracellular channel (CLIC) 4 has diverse functions in membrane trafficking, apoptosis, angiogenesis and cell differentiation. CLIC4 is abundantly expressed in macrophages, but its role in innate immune functions is unclear. Here, we show t
Autor:
Guoan He, Pierre Camateros, Danuta Radzioch, Jennifer Henri, Rafael Marino, Jingxuan Yang, Aihao Ding, Yong Zhong Xu, Thusanth Thuraisingam, Cynthia Kanagaratham
Publikováno v:
The Journal of Immunology. 186:4433-4442
Secretory leukocyte protease inhibitor (SLPI) is an anti-inflammatory protein that is observed at high levels in asthma patients. Resiquimod, a TLR7/8 ligand, is protective against acute and chronic asthma, and it increases SLPI expression of macroph
Autor:
Rebecca Banerjee, Fangfang Yin, Yao Ma, Costantino Iadecola, Ting Jia, Liping Qian, Carl Nathan, Xiaojing Ma, Ping Zhou, M. Flint Beal, Aihao Ding, Bobby Thomas
Publikováno v:
The Journal of Experimental Medicine
Progranulin (PGRN) is a widely expressed protein involved in diverse biological processes. Haploinsufficiency of PGRN in the human causes tau-negative, ubiquitin-positive frontotemporal dementia (FTD). However, the mechanisms are unknown. To explore