Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aierken Abudu"'
Autor:
Krystal Ann Orlando, Amber K Douglas, Aierken Abudu, Yemin Wang, Basile Tessier-Cloutier, Weiping Su, Alec Peters, Larry S Sherman, Rayvon Moore, Vinh Nguyen, Gian Luca Negri, Shane Colborne, Gregg B Morin, Friedrich Kommoss, Jessica D Lang, William PD Hendricks, Elizabeth A Raupach, Patrick Pirrotte, David G Huntsman, Jeffrey M Trent, Joel S Parker, Jesse R Raab, Bernard E Weissman
Publikováno v:
eLife, Vol 9 (2020)
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and aggressive form of ovarian cancer. SCCOHT tumors have inactivating mutations in SMARCA4 (BRG1), one of the two mutually exclusive ATPases of the SWI/SNF chromatin remodeling
Externí odkaz:
https://doaj.org/article/42b0954003194a36bc670b2a11181aaf
Autor:
Sambit Roy, Aierken Abudu, Irving Salinas, Niharika Sinha, Holly Cline-Fedewa, Alexandra M Yaw, Wenjie Qi, Todd A Lydic, Diana L Takahashi, Jon D Hennebold, Hanne M Hoffmann, Jianrong Wang, Aritro Sen
Publikováno v:
Endocrinology. 163
In women, excess androgen causes polycystic ovary syndrome (PCOS), a common fertility disorder with comorbid metabolic dysfunctions including diabetes, obesity, and nonalcoholic fatty liver disease. Using a PCOS mouse model, this study shows that chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b55840ead1c3e81c737a5bfc9cc74eb
https://doi.org/10.1210/endocr/bqac127
https://doi.org/10.1210/endocr/bqac127
Autor:
Krystal Ann Orlando, Amber K Douglas, Aierken Abudu, Yemin Wang, Basile Tessier-Cloutier, Weiping Su, Alec Peters, Larry S Sherman, Rayvon Moore, Vinh Nguyen, Gian Luca Negri, Shane Colborne, Gregg B Morin, Friedrich Kommoss, Jessica D Lang, William PD Hendricks, Elizabeth A Raupach, Patrick Pirrotte, David G Huntsman, Jeffrey M Trent, Joel S Parker, Jesse R Raab, Bernard E Weissman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98d76be8b6e56505f64f17cc33ce41c
https://doi.org/10.7554/elife.59073.sa2
https://doi.org/10.7554/elife.59073.sa2
Autor:
Shane Colborne, Aierken Abudu, Krystal A. Orlando, Alec Peters, Vinh Nguyen, Jesse R. Raab, Amber K. Douglas, Patrick Pirrotte, Friedrich Kommoss, Yemin Wang, Jeffrey M. Trent, Basile Tessier-Cloutier, Jessica D. Lang, Joel S. Parker, Elizabeth A. Raupach, David G. Huntsman, Larry S. Sherman, Bernard E. Weissman, Gregg B. Morin, Gian Luca Negri, William P.D. Hendricks, Rayvon Moore, Weiping Su
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and aggressive form of ovarian cancer. SCCOHT tumors have inactivating mutations in SMARCA4 (BRG1), one of the two mutually exclusive ATPases of the SWI/SNF chromatin remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2279cdd41c21f292f85a10a8731562e3
https://pubmed.ncbi.nlm.nih.gov/33355532
https://pubmed.ncbi.nlm.nih.gov/33355532
Autor:
Sambit Roy, Aierken Abudu, Hanne M. Hoffmann, Kevin L. Childs, Jie Wang, Olivia Nave, Michael T. Sellix, Aritro Sen
Publikováno v:
Journal of the Endocrine Society
In women, excess androgen causes polycystic ovarian syndrome (PCOS), a common fertility disorder with comorbid metabolic dysfunction. A growing body of evidence show that non-alcoholic fatty liver disease (NAFLD) rates are elevated in PCOS women, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2619f009dbb88601dbe4052e878323
https://doi.org/10.1210/js.2019-mon-230
https://doi.org/10.1210/js.2019-mon-230
Autor:
Aierken Abudu, Eugenia Johnson, Michele M. Fluck, Sherif Abd El-Fattah Ibrahim, Neelum Aftab, Susan E. Conrad
Publikováno v:
Oncotarget
Activating protein-1 (AP-1) family members, especially Fra-1 and c-Jun, are highly expressed in invasive cancers and can mediate enhanced migration and proliferation. The aim of this study was to explore the significance of elevated levels of AP-1 fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e81222cd5f67474a825d7d6ded2289
https://pubmed.ncbi.nlm.nih.gov/30774782
https://pubmed.ncbi.nlm.nih.gov/30774782
Publikováno v:
Journal of Biological Chemistry. 287:1220-1228
Discovery of novel antiretroviral mechanism is essential for the design of innovative antiretroviral therapy. Recently, we and others reported that ectopic expression of Moloney leukemia virus 10 (MOV10) protein strongly inhibits retrovirus replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f121c8ed60955d2b8d1a91b4c9690104
https://doi.org/10.1074/jbc.m111.309831
https://doi.org/10.1074/jbc.m111.309831
Autor:
Ying Dang, SungMo Son, Elena Harjes, Hiroshi Matsuo, Paul Spearman, Aierken Abudu, Yong Hui Zheng
Publikováno v:
Journal of Virology. 85:5691-5695
During studies of APOBEC3 (A3) anti-human immunodeficiency virus type 1 (anti-HIV-1) mechanisms, we identified a single cysteine at position 320 (C320) that disrupts A3DE activity. This residue is located in the recently identified DNA binding domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9481836834c25f6202e2b43c8ffb546
https://doi.org/10.1128/jvi.00243-11
https://doi.org/10.1128/jvi.00243-11
Publikováno v:
Journal of Virology. 85:3142-3152
Human APOBEC3H (A3H) has one cytidine deaminase domain (CDD) and inhibits the replication of retrotransposons and human immunodeficiency virus type 1 (HIV-1) in a Vif-resistant manner. Human A3H has five single amino acid polymorphisms (N15Δ, R18L,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc7ebefe0f9a493ae4035cbd2383feb
https://doi.org/10.1128/jvi.02049-10
https://doi.org/10.1128/jvi.02049-10
Autor:
Kotaro Shirakawa, Takashi Uchiyama, Masayuki Kobayashi, Taisuke Izumi, Amane Sasada, Akifumi Takaori-Kondo, Aierken Abudu, Keiko Fukunaga
Publikováno v:
Current biology : CB. 16(15)
Summary APOBEC3G (A3G) is an antiretroviral host factor that functions by deaminating dC to dU in retroviral cDNA [1–5]. HIV-1 Vif protein counteracts A3G via a ubiquitin-proteasome pathway [6–12]. In the case of a simple retrovirus such as the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cb9f4650162936d5caef643c5919a7
https://pubmed.ncbi.nlm.nih.gov/16890533
https://pubmed.ncbi.nlm.nih.gov/16890533