Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Aidong Han"'
Autor:
Mariana Tinajero-Trejo, Oliver Carnell, Azhar F. Kabli, Laia Pasquina-Lemonche, Lucia Lafage, Aidong Han, Jamie K. Hobbs, Simon J. Foster
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The conserved division protein DivIC in the human pathogen Staphylococcus aureus controls cell division through the recruitment of major cell wall synthesis enzymes to the division site.
Externí odkaz:
https://doaj.org/article/45c18fe41033400794e1a8249ae66501
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionDamage to retinal pigment epithelium (RPE) cells caused by oxidative stress is closely related to the pathogenesis of several blinding retinal diseases, such as age-related macular degeneration (AMD), retinitis pigmentosa, and other inher
Externí odkaz:
https://doaj.org/article/8b409669df754c358796c6ab5cf7b18b
Autor:
Lingyuan Kong, Mingyang Su, Jiayan Sang, Shanshan Huang, Min Wang, Yongfei Cai, Mingquan Xie, Jun Wu, Shida Wang, Simon J. Foster, Jiaqin Zhang, Aidong Han
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
In Streptococcus mutans, we find that the histidine kinase WalK possesses the longest C-terminal tail (CTT) among all 14 TCSs, and this tail plays a key role in the interaction of WalK with its response regulator WalR. We demonstrate that the intrins
Externí odkaz:
https://doaj.org/article/5d5f23e0d8dc4d6c920a8452e841ea35
Autor:
Taotao Chen, Zheng Chen, Huimin Wang, Xiaodong Chen, Juanjuan Yang, Aidong Han, Dong-Hai Lin, Jing Hong
Publikováno v:
Journal of Functional Foods, Vol 40, Iss , Pp 606-613 (2018)
A novel antioxidant peptide from protein hydrolysate of Allium tuberosum Rottler was identified as Phe-Pro-Leu-Pro-Ser-Phe (FF-6). It could not only quench multiple radicals efficiently, but also promote cell survival by protecting against oxidative
Externí odkaz:
https://doaj.org/article/60ae59a4c1d64aabbb865d8961255a69
Autor:
Jia Zhang, Suili Wang, Bin Jiang, Lihong Huang, Zhiliang Ji, Xiaotong Li, Huamin Zhou, Aidong Han, Ai Chen, Yanan Wu, Huanhuan Ma, Wentao Zhao, Qingwen Zhao, Changchuan Xie, Xiaoyan Sun, Yanming Zhou, Huiying Huang, Muhammad Suleman, Furong Lin, Lin Zhou, Fang Tian, Meijun Jin, Yana Cai, Nan Zhang, Qinxi Li
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The protein tyrosine kinase c-Src is a renowned proto-oncogene with pleiotropic effects. Here, the authors show that c-Src induces the metabolic reprogramming of cancer cells by phosphorylating hexokinases HK1 and HK2, which in turns lead to increase
Externí odkaz:
https://doaj.org/article/f27b5efb81b84ccd82d03b79c90708b3
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172599 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0166386.].
Externí odkaz:
https://doaj.org/article/c76076a7ab764b309b161621326adf45
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166386 (2016)
Abnormal survival of retinal pigment epithelium (RPE) cells contributes to the pathogenesis of proliferative vitreoretinopathy (PVR), a sight-threatening disease. In this study, we explored the effect of the anti-rheumatic agent auranofin (AF) on RPE
Externí odkaz:
https://doaj.org/article/d4d0072aae22441c83615536558c3715
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133389 (2015)
Two-component signal transduction systems (TCS) are vital for adaptive responses to various environmental stresses in bacteria, fungi and even plants. A TCS typically comprises of a sensor histidine kinase (SK) with its cognate response regulator (RR
Externí odkaz:
https://doaj.org/article/8e0a8edd94db41b88c7e59bb2ee67cfb
Autor:
Chen Wang, Jiayan Sang, Jiawei Wang, Mingyan Su, Jennifer S Downey, Qinggan Wu, Shida Wang, Yongfei Cai, Xiaozheng Xu, Jun Wu, Dilani B Senadheera, Dennis G Cvitkovitch, Lin Chen, Steven D Goodman, Aidong Han
Publikováno v:
PLoS Biology, Vol 11, Iss 2, p e1001493 (2013)
Two-component systems (TCSs) are important for the adaptation and survival of bacteria and fungi under stress conditions. A TCS is often composed of a membrane-bound sensor histidine kinase (SK) and a response regulator (RR), which are relayed throug
Externí odkaz:
https://doaj.org/article/2209811eb85f41de96bc1fa2ffe496cb
Autor:
Tao-Tao Chen, Yanling Lin, Shijun Zhang, Shuxin Liu, Lei Song, Wenhong Zhong, Zhao-Qing Luo, Aidong Han
Publikováno v:
Science Advances. 8
The intracellular bacterial pathogen Legionella pneumophila uses hundreds of effector proteins to manipulate multiple processes of the host cells to establish a replicative niche known as Legionella -containing vacuole (LCV). Biogenesis of the LCV ha