Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Aidi Gao"'
Autor:
Aidi Gao, Mingxia Zhang, Shuang qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-13 (2024)
Abstract Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancer types, with a low 5-year survival rate of ~20%. Our prior research has suggested that DNA Polymerase iota (Pol ι), a member of Y-family DNA polymerase, plays a cruci
Externí odkaz:
https://doaj.org/article/62f9c06512bd4192a699b4d4c3579565
Autor:
Xiaoqing Li, Dexuan Gao, Fei Shen, Hengrui Chen, Zhuqiang Zhang, Chao He, Aidi Gao, Yue Lang, Xiaozhong Zhu, Jundong Zhou, Zeng-Fu Shang, Wei-Qun Ding, Ji Zhu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Radiotherapy resistance is an important and urgent challenge in the clinical management of esophageal squamous carcinoma (ESCC). However, the factors mediating the ESCC resistance to radiotherapy and its underlying molecular mechanisms are n
Externí odkaz:
https://doaj.org/article/86de10f4a735478fb79f810fb4754bee
Autor:
Aidi Gao, Zhenzi Su, Zengfu Shang, Chao He, Dongliu Miao, Xiaoqing Li, Shitao Zou, Weiqun Ding, Yue Zhou, Ming Sun, Jundong Zhou
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/1e4c26d91e4d4cd08425b9730e625923
Autor:
Xiaoqing Li, Shitao Zou, Liangsu Zhou, Aidi Gao, Jing Xu, Chao He, Jundong Zhou, Shuhua Wu, Yihong Chen
Publikováno v:
Cancer Medicine, Vol 11, Iss 20, Pp 3809-3819 (2022)
Abstract Background Radiotherapy has recently become more common for the treatment of esophageal squamous cell carcinoma (ESCC). Radioresistance, on the other hand, continues to be a major issue because it interferes with the effectiveness of ESCC ra
Externí odkaz:
https://doaj.org/article/c4ecdafa983c47ac8ff76a7b84d7ba02
Autor:
Aidi Gao, Zhenzi Su, Zengfu Shang, Chao He, Dongliu Miao, Xiaoqing Li, Shitao Zou, Weiqun Ding, Yue Zhou, Ming Sun, Jundong Zhou
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-11 (2022)
Abstract TAB182 (also named TNKS1BP1), a binding protein of tankyrase 1, has been found to participate in DNA repair. Our previous study has revealed the involvement of TAB182 in the radioresistance of esophageal squamous cell carcinoma (ESCC) cells.
Externí odkaz:
https://doaj.org/article/709df242e65c4c5395cebb07d82971dc
Autor:
Yuandong Cao, Aidi Gao, Xiaoqing Li, Han Min, Chao He, Xinchen Sun, Wei‐Qun Ding, Jundong Zhou
Publikováno v:
Cancer Medicine, Vol 10, Iss 9, Pp 3101-3112 (2021)
Abstract Background Radiotherapy is one of the main strategies for the treatment of esophageal squamous cell carcinoma (ESCC). However, treatment failure often occurs due to the emergence of radioresistance. In this study, we report a key regulator o
Externí odkaz:
https://doaj.org/article/765c4a42965c4ae69f52c6c6ec7b320f
Autor:
Zhenzi Su, Aidi Gao, Xiaoqing Li, Shitao Zou, Chao He, Jinchang Wu, Wei-Qun Ding, Jundong Zhou
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers with rapid progression and a high mortality rate. Our previous study demonstrated that DNA polymerase iota (Pol ι) is overexpressed in ESCC tumors and correlates with poor p
Externí odkaz:
https://doaj.org/article/87a5f708af6e45a1992db341e3fa460e
Autor:
Xinchen Sun, Jundong Zhou, Xiaoqing Li, Yuandong Cao, Chao He, Han Min, Aidi Gao, Wei Qun Ding
Publikováno v:
Cancer Medicine, Vol 10, Iss 9, Pp 3101-3112 (2021)
Cancer Medicine
Cancer Medicine
Background Radiotherapy is one of the main strategies for the treatment of esophageal squamous cell carcinoma (ESCC). However, treatment failure often occurs due to the emergence of radioresistance. In this study, we report a key regulator of radiati
Autor:
Zhonghua Ning, Aidi Gao, Xiaozhong Zhu, Jundong Zhou, Chao He, Chao Gu, Yihong Chen, Wei Qun Ding, Youqin Jiang, Shitao Zou
Publikováno v:
Journal of Cancer
Esophageal squamous cell carcinoma (ESCC) is an aggressive type of cancer with high mortality rate in China, largely due to its high invasive and metastatic potential. The purposes of this study are to investigate the potential molecular mechanisms b
Publikováno v:
Cancer Biomarkers. 24:363-370
BACKGROUND AND OBJECTIVE Dysregulation of DNA polymerase iota (Pol ι) in breast cancer might contribute to the accumulation of genomic mutations and promotes breast cancer progression. In this study we explored the clinical relevance and biological