Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle.

Autor: Mary K McGahon, Janet M Yarham, Aideen Daly, Jasenka Guduric-Fuchs, Lyndsey J Ferguson, David A Simpson, Anthony Collins

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e65809 (2013)

MicroRNAs (miRNAs) are single-stranded non-coding RNAs that negatively regulate target gene expression through mRNA cleavage or translational repression. There is mounting evidence that they play critical roles in heart disease. The expression of kno

Externí odkaz: https://doaj.org/article/4787fbfae99a406297ff8f4556f0c2fb

Hybrid Closed-loop to Manage Gastroparesis in People With Type 1 Diabetes: a Case Series

Autor: Charlotte K. Boughton, Mark L. Evans, Sara Hartnell, Aideen Daly

Publikováno v: Journal of Diabetes Science and Technology

Background: Gastroparesis is associated with unpredictable gastric emptying and can lead to erratic glucose profiles and negative impacts on quality-of-life. Many people with gastroparesis are unable to meet glycemic targets and there is a need for n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304ed4ab6d917ba68b3399e91afb3064
https://pubmed.ncbi.nlm.nih.gov/34378426

Technology in the management of type 2 diabetes: Present status and future prospects

Autor: Roman Hovorka, Aideen Daly

Publikováno v: Diabetes, obesity & metabolism

Funder: This research was funded by the National Institute of Health Research (NIHR) Cambridge Biomedical Research Centre and Wellcome Strategic Award (100574/Z/12/Z). The views expressed are those of the author(s) and not necessarily those of the NI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be76c966776c3dc37d38c7ef3ccc899a
https://www.repository.cam.ac.uk/handle/1810/322744

Day-to-day variability of insulin requirements in the inpatient setting: Observations during fully closed-loop insulin delivery

Autor: Malgorzata E. Wilinska, Charlotte K. Boughton, Andreas Vogt, Aideen Daly, Mark L. Evans, Sara Hartnell, Hood Thabit, David Herzig, Anthony P. Coll, Roman Hovorka, Lia Bally, Yue Ruan

Publikováno v: Boughton, Charlotte K; Daly, Aideen; Thabit, Hood; Hartnell, Sara; Herzig, David; Vogt, Andreas; Ruan, Yue; Wilinska, Malgorzata E; Evans, Mark L; Coll, Anthony P; Bally, Lia; Hovorka, Roman (2021). Day-to-day variability of insulin requirements in the inpatient setting: observations during fully closed-loop insulin delivery. Diabetes, obesity & metabolism, 23(8), pp. 1978-1982. Wiley 10.1111/dom.14396

OBJECTIVE To characterise variability of exogenous insulin requirements during fully closed-loop insulin delivery in hospitalised patients with type 2 diabetes (T2D) or new-onset hyperglycaemia, and to determine patient-related characteristics associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ad5a389f00a18e551e14ed7d48e917
https://pubmed.ncbi.nlm.nih.gov/34105237

Fully automated closed-loop glucose control compared with standard insulin therapy in adults with type 2 diabetes requiring dialysis: an open-label, randomized crossover trial

Autor: Malgorzata E. Wilinska, Andrew Fry, Charlotte K. Boughton, Cecilia Czerlau, David Herzig, Afroditi Tripyla, Lia Bally, Sara Hartnell, Roman Hovorka, Aideen Daly

Publikováno v: Nature Medicine
Boughton, Charlotte K.; Tripyla, Afroditi; Hartnell, Sara; Daly, Aideen; Herzig, David; Wilinska, Malgorzata E.; Czerlau, Cecilia; Fry, Andrew; Bally, Lia; Hovorka, Roman (2021). Fully automated closed-loop glucose control compared with standard insulin therapy in adults with type 2 diabetes requiring dialysis: an open-label, randomized crossover trial. Nature medicine, 27(8), pp. 1471-1476. Nature Publishing Group 10.1038/s41591-021-01453-z

Funder: CB was supported by a grant from The Novo Nordisk UK Research Foundation
Funder: LB was supported by a grant of the Swiss Society for Endocrinology and a grant of the Diabetes and Swiss Kidney Foundation.
Funder: Supported by Nation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aefa8110d1965d7ab39dc49d85d2d4d
https://pubmed.ncbi.nlm.nih.gov/34531573