Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Aidan O'Malley"'
Autor:
Angela Gomez-Simmonds, Medini K. Annavajhala, Zheng Wang, Nenad Macesic, Yue Hu, Marla J. Giddins, Aidan O’Malley, Nora C. Toussaint, Susan Whittier, Victor J. Torres, Anne-Catrin Uhlemann
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Recent reports have established the escalating threat of carbapenem-resistant Enterobacter cloacae complex (CREC). Here, we demonstrate that CREC has evolved as a highly antibiotic-resistant rather than highly virulent nosocomial pathogen. A
Externí odkaz:
https://doaj.org/article/3dfcf99206394211a225caf126f3c080
Autor:
Jeffrey S. Kavanaugh, Lihua Xie, Jessica S. Hook, Alexander R. Horswill, Jessica G. Moreland, Aidan O'Malley, Parth A Patel
Publikováno v:
The Journal of Immunology. 207:966-973
Neutrophils, polymorphonuclear leukocytes (PMN), play a critical role in the innate immune response to Staphylococcus aureus, a pathogen that continues to be associated with significant morbidity and mortality. Neutrophil extracellular trap (NET) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1d4a5fa083e1678ac850f3e59c16714
https://doi.org/10.4049/jimmunol.2100283
https://doi.org/10.4049/jimmunol.2100283
Autor:
Peter T. Buckley, Rita Chan, Jeffrey Fernandez, Jinquan Luo, Keenan A. Lacey, Ashley L. DuMont, Aidan O’Malley, Randall J. Brezski, Songmao Zheng, Thomas Malia, Brian Whitaker, Adam Zwolak, Angela Payne, Desmond Clark, Martin Sigg, Eilyn R. Lacy, Anna Kornilova, Debra Kwok, Steve McCarthy, Bingyuan Wu, Brian Morrow, Jennifer Nemeth-Seay, Ted Petley, Sam Wu, William R. Strohl, Anthony Simon Lynch, Victor J. Torres
Publikováno v:
Cell Host & Microbe. 31:751-765.e11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4756f7a8083a9d7782669668c12b6439
https://doi.org/10.1016/j.chom.2023.04.004
https://doi.org/10.1016/j.chom.2023.04.004
Autor:
Maryaline Coffre, Kayan Tam, Rita Chan, Sergei B. Koralov, Alexis Sommerfield, Keenan A. Lacey, Victor J. Torres, Aidan O’Malley, Joseph C. Devlin, P'ng Loke
Publikováno v:
The Journal of Experimental Medicine
Staphylococcus aureus secretes pore-forming leukocidins that kill leukocytes as part of the bacterium’s evasion strategy. Leukocidin-based vaccination results in toxin-neutralizing antibodies and toxin-specific CD4 lymphocytes that block the toxins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e413afd3f7226c1d97863b40fc944f
http://europepmc.org/articles/PMC7478724
http://europepmc.org/articles/PMC7478724
Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus
Autor:
Jeffrey Fernandez, Anthony Simon Lynch, Rita Chan, William R. Strohl, Victor J. Torres, Angela Payne, William E. Sause, Aidan O’Malley, Ashira Lubkin, Brian Whitaker, Kristina M. Boguslawski, Francis Alonzo, Peter T. Buckley
Publikováno v:
Science Translational Medicine. 11
A key aspect underlying the severity of infections caused by Staphylococcus aureus is the abundance of virulence factors that the pathogen uses to thwart critical components of the human immune response. One such mechanism involves the destruction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d85355373f693d9d3042f20dfa7a0515
https://doi.org/10.1126/scitranslmed.aat0882
https://doi.org/10.1126/scitranslmed.aat0882
Autor:
Aidan O'Malley
2016, as Roy Foster notes in his contribution to this thought-provoking volume, “will be remembered worldwide for far more disruptive events than commemorating a revolution in Ireland.” (39) The as...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdc68ae45447a73e00901dd24d32c7f
https://doi.org/10.1080/09670882.2019.1624360
https://doi.org/10.1080/09670882.2019.1624360
Autor:
Nenad Macesic, Aidan O’Malley, Susan Whittier, Victor J. Torres, Medini K. Annavajhala, Anne-Catrin Uhlemann, Angela Gomez-Simmonds, Yue Hu, Nora C. Toussaint, Zheng Wang, Marla J. Giddins
Publikováno v:
mBio, Vol 9, Iss 3, p e00542-18 (2018)
mBio, Vol 9, Iss 3 (2018)
mBio, 9 (3)
mBio
mBio, Vol 9, Iss 3 (2018)
mBio, 9 (3)
mBio
Recent reports have established the escalating threat of carbapenem-resistant Enterobacter cloacae complex (CREC). Here, we demonstrate that CREC has evolved as a highly antibiotic-resistant rather than highly virulent nosocomial pathogen. Applying g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f5f7d2b41411f5d641732c7a2ab24f
https://doaj.org/article/cfcc9fba15a142f7a502511942afd7e2
https://doaj.org/article/cfcc9fba15a142f7a502511942afd7e2