Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Aidan K. Curran"'
Autor:
David Edwards, Anthony Hickey, Richard Batycky, Lester Griel, Michael Lipp, Wes Dehaan, Robert Clarke, David Hava, Jason Perry, Brendan Laurenzi, Aidan K. Curran, Brandon J. Beddingfield, Chad J. Roy, Tom Devlin, Robert Langer
Publikováno v:
QRB Discovery, Vol 1 (2020)
We propose the nasal administration of calcium-enriched physiological salts as a new hygienic intervention with possible therapeutic application as a response to the rapid and tenacious spread of COVID-19. We test the effectiveness of these salts aga
Externí odkaz:
https://doaj.org/article/d4158dc6a80b4f18a73d82060ce26014
Autor:
Aidan K. Curran, David L. Hava
Publikováno v:
Antibiotics, Vol 10, Iss 4, p 357 (2021)
Aspergillus spp. are spore forming molds; a subset of which are clinically relevant to humans and can cause significant morbidity and mortality. A. fumigatus causes chronic infection in patients with chronic lung disease such as asthma, chronic obstr
Externí odkaz:
https://doaj.org/article/27db7d5d2875421bb83039042782766e
Autor:
Tom Devlin, Robert W. Clarke, Perry Jason M, Anthony J. Hickey, David A. Edwards, Robert Langer, L.C. Griel, Brendan Laurenzi, David L. Hava, Brandon J. Beddingfield, Chad J. Roy, Richard P. Batycky, Aidan K Curran, Wes Dehaan, Michael M. Lipp
Publikováno v:
QRB Discovery
We propose the nasal administration of calcium-enriched physiological salts as a new hygienic intervention with possible therapeutic application as a response to the rapid and tenacious spread of COVID-19. We test the effectiveness of these salts aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d815c35e081bd90afec80374917104
http://europepmc.org/articles/PMC7453358
http://europepmc.org/articles/PMC7453358
Autor:
Gary Layton, Aidan K Curran, Perry Jason M, Pauline Bedwell, Lisa Tan, Katie Kane, Dennis Henderson, Dave Singh, Lucy Connor, Naimat Khan, Litza McKenzie, Patrick J Johnson, David L. Hava, James Roach, Clarie Swann, Steve Kramer
Publikováno v:
Br J Clin Pharmacol
Aims Oral itraconazole has variable pharmacokinetics and risks of adverse events associated with high plasma exposure. An inhalation formulation of itraconazole (PUR1900) is being developed to treat allergic bronchopulmonary aspergillosis, an allergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eecb4856fec17c279879de7deafe96
https://pubmed.ncbi.nlm.nih.gov/31696544
https://pubmed.ncbi.nlm.nih.gov/31696544
Publikováno v:
Airway pharmacology and treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240c5fdfcbda807ece91a6f6d84cf450
https://doi.org/10.1183/13993003.congress-2018.pa5247
https://doi.org/10.1183/13993003.congress-2018.pa5247
Autor:
Mutsumi Miyamoto, Johan Verbeeck, Gareth Thomas, Michael K. Pugsley, Jennifer L. Ingram-Ross, Birgit Verstynen, J. Sheehan, Aidan K. Curran, Eric J. de Waal
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 66:114-124
Introduction This study was designed to provide a comprehensive nonclinical respiratory safety pharmacology assessment using respiratory inductance plethysmography (RIP) concomitant with a standard cardiovascular (CV) safety assessment in non-human p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549b668149659d875c5c5e0f4fb095a4
https://doi.org/10.1016/j.vascn.2012.04.002
https://doi.org/10.1016/j.vascn.2012.04.002
Autor:
Aileen House, Jennifer Richard, Brian Salisbury, Richard W. Chapman, John C. Anthes, John C. Hunter, Aidan K. Curran, Jonathan E. Phillips
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 24:67-73
Mometasone furoate (MF)/formoterol fumarate (F) combination is a new inhaIed corticosteroid/long-acting β₂-adrenergic agonist (ICS/LABA). The purpose of this study was to evaluate the effects of different dose combinations of MF/F on a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8265c2458de283ee81f4861678249ac
https://doi.org/10.1016/j.pupt.2010.10.002
https://doi.org/10.1016/j.pupt.2010.10.002
Autor:
James C. Leiter, Aidan K. Curran
Publikováno v:
Experimental Physiology. 92:757-767
Inhibition of neurones in the ventral medulla accentuates the respiratory inhibition associated with acute blood pressure elevation in piglets. Activation of presynaptic 5-HT1A receptors inhibits serotonergic neurones in the ventral medulla and cauda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ad9efc56d452f164078c46ccf79d12c
https://doi.org/10.1113/expphysiol.2007.037481
https://doi.org/10.1113/expphysiol.2007.037481
Autor:
Liesbeth van der Velde, Robert A. Darnall, Donald Bartlett, James C. Leiter, Aidan K. Curran, James J. Filiano
Publikováno v:
Journal of Applied Physiology. 94:1883-1895
We tested the hypothesis that inhibition of neurons within the rostral ventral medulla (RVM) would prolong the laryngeal chemoreflex (LCR), a putative stimulus in the sudden infant death syndrome (SIDS). We studied the LCR in 19 piglets, age 3–16 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a5a4f34bbad3aa31e3736b800e71f1
https://doi.org/10.1152/japplphysiol.01103.2002
https://doi.org/10.1152/japplphysiol.01103.2002
Publikováno v:
Journal of Applied Physiology. 92:2554-2564
The rostral ventral medulla (RVM) may be important in the control of cardiorespiratory interactions. We hypothesized that inhibition of the RVM would enhance inhibition of breathing associated with transient blood pressure elevations. In 25 piglets 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7348f633119814e97a21cd3295486c05
https://doi.org/10.1152/japplphysiol.00895.2001
https://doi.org/10.1152/japplphysiol.00895.2001