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pro vyhledávání: '"Aidan Joblin-Mills"'
Autor:
Aidan Joblin-Mills, Zhanxuan E. Wu, Ivana R. Sequeira-Bisson, Jennifer L. Miles-Chan, Sally D. Poppitt, Karl Fraser
Publikováno v:
Metabolites, Vol 14, Iss 6, p 313 (2024)
Biological samples of lipids and metabolites degrade after extensive years in −80 °C storage. We aimed to determine if associated multivariate models are also impacted. Prior TOFI_Asia metabolomics studies from our laboratory established multivari
Externí odkaz:
https://doaj.org/article/a2f7ed29bfdb4615a6bfa2fe2d98350a
Autor:
Aidan Joblin-Mills, Zhanxuan Wu, Karl Fraser, Beatrix Jones, Wilson Yip, Jia Jiet Lim, Louise Lu, Ivana Sequeira, Sally Poppitt
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 3 (2022)
The “Thin on the Outside Fat on the Inside” TOFI_Asia study found Asian Chinese to be more susceptible to Type 2 Diabetes (T2D) compared to European Caucasians matched for gender and body mass index (BMI). This was influenced by degree of viscera
Externí odkaz:
https://doaj.org/article/09bc6b360ec24c409a219ac6bfa3b4eb
Autor:
Jonnell C. Small, Aidan Joblin-Mills, Kaycee Carbone, Maria Kost-Alimova, Kumiko Ayukawa, Carol Khodier, Vlado Dancik, Paul A. Clemons, Andrew B. Munkacsi, Bridget K. Wagner
Publikováno v:
ACS Chemical Biology. 17:1131-1142
Type 2 diabetes is marked by progressive β-cell failure, leading to loss of β-cell mass. Increased levels of circulating glucose and free fatty acids associated with obesity lead to β-cell glucolipotoxicity. There are currently no therapeutic opti
Autor:
Stephen L. Sturley, James Moon, Joyce J. Repa, Jeanne Garbarino, Daniel J. Rader, Andrew B. Munkacsi, Ying Liu, Mark A. Valasek, Dawn Marchadier, Aidan Joblin-Mills, John S. Millar, Kelly V. Ruggles, Annette L. Henneberry, Jeff Billheimer, Kerry Schneider, Sonia Gulati
The toxic subcellular accumulation of lipids predisposes several human metabolic syndromes, including obesity, type 2 diabetes, and some forms of neurodegeneration. To identify pathways that prevent lipid-induced cell death, we performed a genome-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d6c65cad52ac51f8cad0e3f33ebe71
https://europepmc.org/articles/PMC3924304/
https://europepmc.org/articles/PMC3924304/