Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Aidan J O'Donnell"'
Autor:
Kimberley F Prior, Daan R van der Veen, Aidan J O'Donnell, Katherine Cumnock, David Schneider, Arnab Pain, Amit Subudhi, Abhinay Ramaprasad, Samuel S C Rund, Nicholas J Savill, Sarah E Reece
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006900 (2018)
Circadian rhythms enable organisms to synchronise the processes underpinning survival and reproduction to anticipate daily changes in the external environment. Recent work shows that daily (circadian) rhythms also enable parasites to maximise fitness
Externí odkaz:
https://doaj.org/article/bdfcdfcc0fb04b8fb3d1251aa5bdfd5d
Publikováno v:
Frontiers in Malaria, Vol 2 (2024)
Parasites rely on exploiting resources from their hosts and vectors for survival and transmission. This includes nutritional resources, which vary in availability between different hosts and changes during infections. For malaria (Plasmodium) parasit
Externí odkaz:
https://doaj.org/article/a00101fec41d4325b673527fc852940b
Publikováno v:
Evolutionary Applications, Vol 17, Iss 7, Pp n/a-n/a (2024)
Abstract Undertaking certain activities at the time of day that maximises fitness is assumed to explain the evolution of circadian clocks. Organisms often use daily environmental cues such as light and food availability to set the timing of their clo
Externí odkaz:
https://doaj.org/article/3af4ffd86f3545489648e39328831247
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Biological rhythms allow organisms to compartmentalise and coordinate behaviours, physiologies, and cellular processes with the predictable daily rhythms of their environment. There is increasing recognition that the biological rh
Externí odkaz:
https://doaj.org/article/63d2f501b1fa4b0ea1e029a3699acc99
Autor:
Cédric Lippens, Emmanuel Guivier, Sarah E. Reece, Aidan J. O’Donnell, Stéphane Cornet, Bruno Faivre, Gabriele Sorci
Publikováno v:
Evolutionary Applications, Vol 12, Iss 2, Pp 314-323 (2019)
Abstract Aging is associated with a decline of performance leading to reduced reproductive output and survival. While the antagonistic pleiotropy theory of aging has attracted considerable attention, the molecular/physiological functions underlying t
Externí odkaz:
https://doaj.org/article/46eaa50cd96b4dd6ab14278f06b2643b
Autor:
Abhinav Kaushik, Fathia Ben Rached, Amit Kumar Subudhi, Richard Culleton, Sarah E. Reece, Alyaa M. Abdel-Haleem, Hussein M. Abkallo, Hifzur Rahman Ansari, Arnab Pain, Osamu Kaneko, Aidan J. O’Donnell, Abhinay Ramaprasad
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Malaria parasites complete their intra-erythrocytic developmental cycle (IDC) in multiples of 24 h suggesting a circadian basis, but the mechanism controlling this periodicity is unknown. Combining in vivo and in vitro approaches utilizing rodent and
Autor:
Gregory F. Albery, Kimberley F. Prior, Sarah E. Reece, Aidan J. O’Donnell, Petra Schneider, Mary L. Westwood
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Malaria Journal
Westwood, M, O'Donnell, A, Schneider, P, Albery, G, Prior, K & Reece, S 2020, ' Testing possible causes of gametocyte reduction in temporally out-of-synch malaria infections ', Malaria Journal, vol. 19, 17 . https://doi.org/10.1186/s12936-020-3107-1
Malaria Journal
Westwood, M, O'Donnell, A, Schneider, P, Albery, G, Prior, K & Reece, S 2020, ' Testing possible causes of gametocyte reduction in temporally out-of-synch malaria infections ', Malaria Journal, vol. 19, 17 . https://doi.org/10.1186/s12936-020-3107-1
Background The intraerythrocytic development cycle (IDC) of the rodent malaria Plasmodium chabaudi is coordinated with host circadian rhythms. When this coordination is disrupted, parasites suffer a 50% reduction in both asexual stages and sexual sta
Publikováno v:
O’Donnell, A J, Greischar, M A & Reece, S E 2021, ' Mistimed malaria parasites re-synchronise with host feeding-fasting rhythms by shortening the duration of intra-erythrocytic development ', Parasite Immunology . https://doi.org/10.1111/pim.12898
AimsMalaria parasites exhibit daily rhythms in the intraerythrocytic development cycle (IDC) that underpins asexual replication in the blood. The IDC schedule is aligned with the timing of host feeding-fasting rhythms. When the IDC schedule is pertur
Autor:
Kimberley F. Prior, Benita Middleton, Alíz T.Y. Owolabi, Mary L. Westwood, Jacob Holland, Aidan J. O'Donnell, Michael J. Blackman, Debra J. Skene, Sarah E. Reece
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: Rapid asexual replication of blood stage malaria parasites is responsible for the severity of disease symptoms and fuels the production of transmission forms. Here, we demonstrate that a Plasmodium chabaudi’s schedule for asexual replic