Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Aidan J O'Donnell"'
Publikováno v:
Frontiers in Malaria, Vol 2 (2024)
Parasites rely on exploiting resources from their hosts and vectors for survival and transmission. This includes nutritional resources, which vary in availability between different hosts and changes during infections. For malaria (Plasmodium) parasit
Externí odkaz:
https://doaj.org/article/a00101fec41d4325b673527fc852940b
Publikováno v:
Evolutionary Applications, Vol 17, Iss 7, Pp n/a-n/a (2024)
Abstract Undertaking certain activities at the time of day that maximises fitness is assumed to explain the evolution of circadian clocks. Organisms often use daily environmental cues such as light and food availability to set the timing of their clo
Externí odkaz:
https://doaj.org/article/3af4ffd86f3545489648e39328831247
Autor:
Aidan J. O’Donnell, Sarah E. Reece
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Daily periodicity in the diverse activities of parasites occurs across a broad taxonomic range. The rhythms exhibited by parasites are thought to be adaptations that allow parasites to cope with, or exploit, the consequences of ho
Externí odkaz:
https://doaj.org/article/7be2818566e34aa9b2c37aa6b64f4aae
Autor:
Amit K. Subudhi, Aidan J. O’Donnell, Abhinay Ramaprasad, Hussein M. Abkallo, Abhinav Kaushik, Hifzur R. Ansari, Alyaa M. Abdel-Haleem, Fathia Ben Rached, Osamu Kaneko, Richard Culleton, Sarah E. Reece, Arnab Pain
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The mechanism underlying periodicity of Plasmodium’s intra-erythrocytic developmental cycle (IDC) is unclear. Here, Subudhi et al. show that serpentine receptor 10 (SR10) plays a role in regulating the schedule of the IDC in line with the timing of
Externí odkaz:
https://doaj.org/article/054dfacd7e3f4feb8fed1b8517913e0a
Autor:
Mary L. Westwood, Aidan J. O’Donnell, Petra Schneider, Gregory F. Albery, Kimberley F. Prior, Sarah E. Reece
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background The intraerythrocytic development cycle (IDC) of the rodent malaria Plasmodium chabaudi is coordinated with host circadian rhythms. When this coordination is disrupted, parasites suffer a 50% reduction in both asexual stages and s
Externí odkaz:
https://doaj.org/article/f0b66085777543af9bf7cb82c3a99f1b
Autor:
Kimberley F. Prior, Benita Middleton, Alíz T.Y. Owolabi, Mary L. Westwood, Jacob Holland, Aidan J. O'Donnell, Michael J. Blackman, Debra J. Skene, Sarah E. Reece
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: Rapid asexual replication of blood stage malaria parasites is responsible for the severity of disease symptoms and fuels the production of transmission forms. Here, we demonstrate that a Plasmodium chabaudi’s schedule for asexual replic
Externí odkaz:
https://doaj.org/article/15e9db7e34144d7dac9cd75b576f119d
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Biological rhythms allow organisms to compartmentalise and coordinate behaviours, physiologies, and cellular processes with the predictable daily rhythms of their environment. There is increasing recognition that the biological rh
Externí odkaz:
https://doaj.org/article/63d2f501b1fa4b0ea1e029a3699acc99
Autor:
Cédric Lippens, Emmanuel Guivier, Sarah E. Reece, Aidan J. O’Donnell, Stéphane Cornet, Bruno Faivre, Gabriele Sorci
Publikováno v:
Evolutionary Applications, Vol 12, Iss 2, Pp 314-323 (2019)
Abstract Aging is associated with a decline of performance leading to reduced reproductive output and survival. While the antagonistic pleiotropy theory of aging has attracted considerable attention, the molecular/physiological functions underlying t
Externí odkaz:
https://doaj.org/article/46eaa50cd96b4dd6ab14278f06b2643b
Autor:
Kimberley F Prior, Daan R van der Veen, Aidan J O'Donnell, Katherine Cumnock, David Schneider, Arnab Pain, Amit Subudhi, Abhinay Ramaprasad, Samuel S C Rund, Nicholas J Savill, Sarah E Reece
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006900 (2018)
Circadian rhythms enable organisms to synchronise the processes underpinning survival and reproduction to anticipate daily changes in the external environment. Recent work shows that daily (circadian) rhythms also enable parasites to maximise fitness
Externí odkaz:
https://doaj.org/article/bdfcdfcc0fb04b8fb3d1251aa5bdfd5d
Autor:
Abhinav Kaushik, Fathia Ben Rached, Amit Kumar Subudhi, Richard Culleton, Sarah E. Reece, Alyaa M. Abdel-Haleem, Hussein M. Abkallo, Hifzur Rahman Ansari, Arnab Pain, Osamu Kaneko, Aidan J. O’Donnell, Abhinay Ramaprasad
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Malaria parasites complete their intra-erythrocytic developmental cycle (IDC) in multiples of 24 h suggesting a circadian basis, but the mechanism controlling this periodicity is unknown. Combining in vivo and in vitro approaches utilizing rodent and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215b3cc10a6dfefcb535f045ae6dc40e
https://doaj.org/article/054dfacd7e3f4feb8fed1b8517913e0a
https://doaj.org/article/054dfacd7e3f4feb8fed1b8517913e0a