Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Aidan G. Gilmartin"'
Autor:
Aidan G. Gilmartin, Arthur Groy, Elizabeth R. Gore, Charity Atkins, Edward R. Long, Monica N. Montoute, Zining Wu, Wendy Halsey, Dean E. McNulty, Daniela Ennulat, Lourdes Rueda, Melissa Pappalardi, Ryan G. Kruger, Michael T. McCabe, Ali Raoof, Roger Butlin, Alexandra Stowell, Mark Cockerill, Ian Waddell, Donald Ogilvie, Juan Luengo, Allan Jordan, Andrew B. Benowitz
Publikováno v:
Haematologica, Vol 106, Iss 7 (2020)
Pharmacological induction of fetal hemoglobin (HbF) expression is an effective therapeutic strategy for the management of beta-hemoglobinopathies such as sickle cell disease. DNA methyltransferase (DNMT) inhibitors 5-azacytidine (5-aza) and 5-aza-2
Externí odkaz:
https://doaj.org/article/375cf7300ce44f4d81582faca63eef19
Autor:
Sylvie G. Laquerre, David Sutton, Roland Annan, Francesca Zappacosta, Jingsong Yang, Kelly E. Fisher, Symon Erskine, Cynthia M. Rominger, Swarupa G. Kulkarni, Elisabeth A. Minthorn, Katherine G. Moss, Arthur Groy, Maureen R. Bleam, Aidan G. Gilmartin
Supplementary Figures S1-S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7058b2fa24465f2173cd06088172f582
https://doi.org/10.1158/1078-0432.22443324.v1
https://doi.org/10.1158/1078-0432.22443324.v1
Autor:
Richard Wooster, Barbara Weber, Jeffrey Jackson, Kurtis Bachman, Scott Powers, Nancy Liu-Sullivan, Christopher Moy, Ashley Hughes, Wendy Halsey, Maureen Bleam, Xiping Zhang, Mark Richter, Junping Jing, Aidan G. Gilmartin, Sylvie Laquerre, Joel Greshock, Yan Degenhardt
Supplementary Tables 1-5 from Sensitivity of Cancer Cells to Plk1 Inhibitor GSK461364A Is Associated with Loss of p53 Function and Chromosome Instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473cc85ee7dc604cf29a7644dabe7a47
https://doi.org/10.1158/1535-7163.22485417.v1
https://doi.org/10.1158/1535-7163.22485417.v1
Autor:
Richard Wooster, Barbara Weber, Jeffrey Jackson, Kurtis Bachman, Scott Powers, Nancy Liu-Sullivan, Christopher Moy, Ashley Hughes, Wendy Halsey, Maureen Bleam, Xiping Zhang, Mark Richter, Junping Jing, Aidan G. Gilmartin, Sylvie Laquerre, Joel Greshock, Yan Degenhardt
Supplementary Figure 1 from Sensitivity of Cancer Cells to Plk1 Inhibitor GSK461364A Is Associated with Loss of p53 Function and Chromosome Instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1217c9149d49a2333517ac575554062e
https://doi.org/10.1158/1535-7163.22485420.v1
https://doi.org/10.1158/1535-7163.22485420.v1
Autor:
Sylvie G. Laquerre, David Sutton, Roland Annan, Francesca Zappacosta, Jingsong Yang, Kelly E. Fisher, Symon Erskine, Cynthia M. Rominger, Swarupa G. Kulkarni, Elisabeth A. Minthorn, Katherine G. Moss, Arthur Groy, Maureen R. Bleam, Aidan G. Gilmartin
Purpose: Despite their preclinical promise, previous MEK inhibitors have shown little benefit for patients. This likely reflects the narrow therapeutic window for MEK inhibitors due to the essential role of the P42/44 MAPK pathway in many nontumor ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d39348d02bb57cb5edbc2432031aee
https://doi.org/10.1158/1078-0432.c.6519777
https://doi.org/10.1158/1078-0432.c.6519777
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Supplementary Tables 1-3 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63807349d8c5365b462bb33763b38e0
https://doi.org/10.1158/0008-5472.22378532.v1
https://doi.org/10.1158/0008-5472.22378532.v1
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Supplementary Figure Legends 1-4 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680e0f17f3ce8cc74f754d82f38def5e
https://doi.org/10.1158/0008-5472.22378538.v1
https://doi.org/10.1158/0008-5472.22378538.v1
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Supplementary Figures 1-4 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ad8ebae32a794098ee99c407b72872
https://doi.org/10.1158/0008-5472.22378535.v1
https://doi.org/10.1158/0008-5472.22378535.v1
Autor:
Sylvie G. Laquerre, Jeffrey R. Jackson, Melody A. Diamond, David Sutton, Mary P. Courtney, Richard R. Gontarek, Gary K. Smith, Daniel F. Hassler, Lenore Madden, Ryan G. Kruger, Symon G. Erskine, Mark C. Richter, Maureen R. Bleam, Aidan G. Gilmartin
Additions to Supplement Table 3 from Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2382019a7bca7fdff5e1920fcfcedfa6
https://doi.org/10.1158/0008-5472.22378544.v1
https://doi.org/10.1158/0008-5472.22378544.v1
Autor:
Peter A. Jones, Ashley K. Wiseman, Helai P. Mohammad, Christopher S. Kershaw, Bryan W. King, Ian D. Waddell, Thau F. Ho, Stephen B. Baylin, Morris Muliaditan, Marcus Bantscheff, Elisabeth A. Minthorn, Thilo Werner, Alan P. Graves, Wendy A. Kellner, Phil Chapman, Mehul Patel, Anthony J. Jurewicz, Allan M. Jordan, Emma E. Fairweather, Rab K. Prinjha, Nino Campobasso, Anna Rutkowska, H. Christian Eberl, Ryan G. Kruger, Charles F. McHugh, Michael T. McCabe, Kristin M. Goldberg, Jon Paul Jaworski, Christopher L. Carpenter, Michael Steidel, Stuart Paul Romeril, Dirk A. Heerding, Lourdes Rueda, David T. Fosbenner, Amy N. Taylor, Jacques Briand, Shawn W. Foley, Arthur Groy, Andrew B. Benowitz, Xiaodong Cheng, Donald J. Ogilvie, Paola Grandi, Cunyu Zhang, Mei Li, Sarath Pathuri, Aidan G. Gilmartin, Christian S. Sherk, Juan I. Luengo, Mark Cockerill, Ali Raoof, Alexandra Stowell, Kathryn Keenan, Melissa B. Pappalardi, Makda Mebrahtu, Kristen Wong, Xing Zhang, Jessica L. Handler, Roger J. Butlin, John R. Horton, Susan Merrihew, Charlotte Burt, Dean E. McNulty
Publikováno v:
Nature Cancer. 2:1002-1017
DNA methylation, a key epigenetic driver of transcriptional silencing, is universally dysregulated in cancer. Reversal of DNA methylation by hypomethylating agents, such as the cytidine analogs decitabine or azacytidine, has demonstrated clinical ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44c950954b0f6c38dfa2b274f54f21b
https://doi.org/10.1038/s43018-021-00249-x
https://doi.org/10.1038/s43018-021-00249-x