A novel GPER antagonist protects against the formation of estrogen-induced cholesterol gallstones in female mice

Autor: Chelsea DeLeon, Helen H. Wang, Joseph Gunn, McKenna Wilhelm, Aidan Cole, Stacy Arnett, David Q-H. Wang, Christopher K. Arnatt

Publikováno v: Journal of Lipid Research, Vol 61, Iss 5, Pp 767-777 (2020)

Many clinical studies and epidemiological investigations have clearly demonstrated that women are twice as likely to develop cholesterol gallstones as men, and oral contraceptives and other estrogen therapies dramatically increase that risk. Further,

Externí odkaz: https://doaj.org/article/5630faffec284745a5663911943e8dce

Lithium stabilization of amorphous ZrO2

Autor: Stephens, Gareth F., Wilson, Jack A., Curling, Simon F., He, Guanze, Thomas, P. John, Williams, David W., Ortner, Susan, Grovenor, Chris, Rushton, Michael J.D., Baker, Aidan Cole, Middleburgh, Simon C.

Publikováno v: In Progress in Nuclear Energy June 2024 171

Supplementary figure SF4 from Toxicity and Efficacy of Concurrent Androgen Deprivation Therapy, Pelvic Radiotherapy, and Radium-223 in Patients with De Novo Metastatic Hormone-Sensitive Prostate Cancer

Autor: Joe M. O'Sullivan, Sandra Biggart, Conor K. McGarry, Alan R. Hounsell, Kevin M. Prise, Darren Mitchell, Arthur Grey, Aidan Cole, Suneil Jain, Philip G. Turner

Supplementary figure SF4 shows (A) Kaplan-Meier plot to estimate median progression free survival as time from first docetaxel (or trial registration if no docetaxel received) until PSA progression per PCWG. Median progression free survival = 20.5 mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd778b7057e540b59dbae78c82834e9
https://doi.org/10.1158/1078-0432.22480730

A Randomized Feasibility Trial of Stereotactic Prostate Radiation Therapy With or Without Elective Nodal Irradiation in High-Risk Localized Prostate Cancer (SPORT Trial)

Autor: Orla A. Houlihan, Kelly Redmond, Ciaran Fairmichael, Ciara A. Lyons, Conor K. McGarry, Darren Mitchell, Aidan Cole, John O'Connor, Stephen McMahon, Denise Irvine, Wendy Hyland, Michael Hanna, Kevin M. Prise, Alan R. Hounsell, Joe M. O'Sullivan, Suneil Jain

Publikováno v: International Journal of Radiation Oncology*Biology*Physics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97ab1de342e56b8003db62f28e31b52e
https://doi.org/10.1016/j.ijrobp.2023.02.054

Enhancing authenticity, diagnosticity and e quivalence (AD-Equiv) in multicentre OSCE exams in health professionals education: protocol for a complex intervention study

Autor: Peter Yeates, Adriano Maluf, Ruth Kinston, Natalie Cope, Gareth McCray, Kathy Cullen, Vikki O’Neill, Aidan Cole, Rhian Goodfellow, Rebecca Vallender, Ching-Wa Chung, Robert K McKinley, Richard Fuller, Geoff Wong

Publikováno v: Yeates, P, Maluf, A, Kinston, R, Cope, N, McCray, G, Cullen, K, O’Neill, V, Cole, A, Goodfellow, R, Vallender, R, Chung, C-W, McKinley, R K, Fuller, R & Wong, G 2022, ' Enhancing authenticity, diagnosticity and e quivalence (AD-Equiv) in multicentre OSCE exams in health professionals education: protocol for a complex intervention study ', BMJ Open, vol. 12, no. 12, e064387 . https://doi.org/10.1136/bmjopen-2022-064387

IntroductionObjective structured clinical exams (OSCEs) are a cornerstone of assessing the competence of trainee healthcare professionals, but have been criticised for (1) lacking authenticity, (2) variability in examiners’ judgements which can cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d69019bb9bad104f85b4b5deadd21d
https://pure.qub.ac.uk/en/publications/3162b130-c358-4aaa-a8ad-03456c1ac447