Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Aida M Andrés"'
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010337 (2022)
Central and eastern chimpanzees are infected with Simian Immunodeficiency Virus (SIV) in the wild, typically without developing acute immunodeficiency. Yet the recent zoonotic transmission of chimpanzee SIV to humans, which were naïve to the virus,
Externí odkaz:
https://doaj.org/article/5429e5ccd5ed4f60a321ecd069bf3000
Publikováno v:
PLoS Genetics, Vol 15, Iss 11, p e1008485 (2019)
Chimpanzees, humans' closest relatives, are in danger of extinction. Aside from direct human impacts such as hunting and habitat destruction, a key threat is transmissible disease. As humans continue to encroach upon their habitats, which shrink in s
Externí odkaz:
https://doaj.org/article/a0e752aa19c144d3998fbb7c92ec8a6f
Autor:
Felix M Key, Muslihudeen A Abdul-Aziz, Roger Mundry, Benjamin M Peter, Aarthi Sekar, Mauro D'Amato, Megan Y Dennis, Joshua M Schmidt, Aida M Andrés
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007298 (2018)
Ambient temperature is a critical environmental factor for all living organisms. It was likely an important selective force as modern humans recently colonized temperate and cold Eurasian environments. Nevertheless, as of yet we have limited evidence
Externí odkaz:
https://doaj.org/article/9dfb8c5290ce45af85e3f4b1c8a71d22
Autor:
Felix M Key, Benjamin Peter, Megan Y Dennis, Emilia Huerta-Sánchez, Wei Tang, Ludmila Prokunina-Olsson, Rasmus Nielsen, Aida M Andrés
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004681 (2014)
Interferon lambda 4 gene (IFNL4) encodes IFN-λ4, a new member of the IFN-λ family with antiviral activity. In humans IFNL4 open reading frame is truncated by a polymorphic frame-shift insertion that eliminates IFN-λ4 and turns IFNL4 into a polymor
Externí odkaz:
https://doaj.org/article/fce6bb6d42854435bc44e5275459263b
Autor:
Aida M Andrés, Megan Y Dennis, Warren W Kretzschmar, Jennifer L Cannons, Shih-Queen Lee-Lin, Belen Hurle, NISC Comparative Sequencing Program, Pamela L Schwartzberg, Scott H Williamson, Carlos D Bustamante, Rasmus Nielsen, Andrew G Clark, Eric D Green
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001157 (2010)
A remarkable characteristic of the human major histocompatibility complex (MHC) is its extreme genetic diversity, which is maintained by balancing selection. In fact, the MHC complex remains one of the best-known examples of natural selection in huma
Externí odkaz:
https://doaj.org/article/dcc509bf91b64ef3b174824a0c207b08
Publikováno v:
Genome Biology and Evolution. 15
The identification of genomic regions and genes that have evolved under natural selection is a fundamental objective in the field of evolutionary genetics. While various approaches have been established for the detection of targets of positive select
Ancient loss of catalytic selenocysteine spurred convergent adaptation in a mammalian oxidoreductase
Autor:
Jasmin Rees, Gaurab Sarangi, Qing Cheng, Martin Floor, Aida M Andrés, Baldomero Oliva Miguel, Jordi Villà-Freixa, Elias SJ Arnér, Sergi Castellano
Selenocysteine (Sec), the 21stamino acid specified by the genetic code, is a rare selenium-containing residue found in the catalytic site of selenoprotein oxidoreductases. Sec is analogous to the common cysteine (Cys) amino acid but its selenium atom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2b8f0d9be65837ae98a2fa7dc2f31d
https://doi.org/10.1101/2023.01.03.522577
https://doi.org/10.1101/2023.01.03.522577
Publikováno v:
Trends in Genetics. 36:415-428
Modern humans inhabit a variety of environments and are exposed to a plethora of selective pressures, leading to multiple genetic adaptations to local environmental conditions. These include adaptations to climate, UV exposure, disease, diet, altitud
Publikováno v:
PLoS genetics. 18(8)
Central and eastern chimpanzees are infected with Simian Immunodeficiency Virus (SIV) in the wild, typically without developing acute immunodeficiency. Yet the recent zoonotic transmission of chimpanzee SIV to humans, which were naïve to the virus,