Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Aida Llucià-Valldeperas"'
1
Akademický článek
Mechanical stimulation of induced pluripotent stem cell derived cardiac fibroblasts
Autor: Fjodor T. Bekedam, Rowan Smal, Marisa C. Smit, Jurjan Aman, Anton Vonk-Noordegraaf, Harm Jan Bogaard, Marie José Goumans, Frances S. De Man, Aida Llucià-Valldeperas
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cardiac fibrosis contributes to the development of heart failure, and is the response of cardiac fibroblasts (CFs) to pressure or volume overload. Limiting factors in CFs research are the poor availability of human cells and the tendency of
Externí odkaz: https://doaj.org/article/585c620b0a47474eb2356249f8333fef
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3
Akademický článek
The thromboxane receptor antagonist NTP42 promotes beneficial adaptation and preserves cardiac function in experimental models of right heart overload
Autor: Eamon P. Mulvaney, Fabiana Renzo, Rui Adão, Emilie Dupre, Lucia Bialesova, Viviana Salvatore, Helen M. Reid, Glória Conceição, Julien Grynblat, Aida Llucià-Valldeperas, Jean-Baptiste Michel, Carmen Brás-Silva, Charles E. Laurent, Luke S. Howard, David Montani, Marc Humbert, Anton Vonk Noordegraaf, Frédéric Perros, Pedro Mendes-Ferreira, B. Therese Kinsella
Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundPulmonary arterial hypertension (PAH) is a progressive disease characterized by increased pulmonary artery pressure leading to right ventricular (RV) failure. While current PAH therapies improve patient outlook, they show limited benefit in
Externí odkaz: https://doaj.org/article/61ac0e73143f434fb6aee88b5fe3d60f
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4
Akademický článek
Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations
Autor: Aida Llucià-Valldeperas, Rowan Smal, Fjodor T. Bekedam, Margaux Cé, Xiaoke Pan, Xue D. Manz, Paul J. M. Wijnker, Anton Vonk-Noordegraaf, Harm J. Bogaard, Marie-Jose Goumans, Frances S. de Man
Publikováno v: Cells, Vol 10, Iss 12, p 3595 (2021)
Pulmonary arterial hypertension (PAH) patients eventually die of right heart failure (RHF). Currently, there is no suitable pre-clinical model to study PAH. Therefore, we aim to develop a right heart dysfunction (RHD) model using the 3-dimensional en
Externí odkaz: https://doaj.org/article/6731cce43fa04dcfaec93b7219fc2b1a
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5
Akademický článek
A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function
Autor: Isaac Perea-Gil, MS, Cristina Prat-Vidal, PhD, Carolina Gálvez-Montón, DVM, PhD, Santiago Roura, PhD, Aida Llucià-Valldeperas, PhD, Carolina Soler-Botija, PhD, Oriol Iborra-Egea, MS, Idoia Díaz-Güemes, DVM, PhD, Verónica Crisóstomo, DVM, PhD, Francisco M. Sánchez-Margallo, DVM, PhD, Antoni Bayes-Genis, MD, PhD
Publikováno v: JACC: Basic to Translational Science, Vol 1, Iss 5, Pp 360-372 (2016)
Myocardial infarction (MI) remains a dreadful disease around the world, causing irreversible sequelae that shorten life expectancy and reduce quality of life despite current treatment. Here, the authors engineered a cell-enriched myocardial graft, co
Externí odkaz: https://doaj.org/article/bac55280760c45a7895fad68a7452975
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6
Akademický článek
Human umbilical cord blood-derived mesenchymal stem cells promote vascular growth in vivo.
Autor: Santiago Roura, Juli R Bagó, Carolina Soler-Botija, Josep M Pujal, Carolina Gálvez-Montón, Cristina Prat-Vidal, Aida Llucià-Valldeperas, Jerónimo Blanco, Antoni Bayes-Genis
Publikováno v: PLoS ONE, Vol 7, Iss 11, p e49447 (2012)
Stem cell therapies are promising strategies to regenerate human injured tissues, including ischemic myocardium. Here, we examined the acquisition of properties associated with vascular growth by human umbilical cord blood-derived mesenchymal stem ce
Externí odkaz: https://doaj.org/article/7216f670f728488a8073734c4bb14404
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7
The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload
Autor: G J du Marchie Sarvaas, Ella M. Poels, Paula A. da Costa Martins, Rudolphus Berger, Lara Ottaviani, C Dos Remedios, F S De Man, L. J. de Windt, Anne-Marie C. Koop, André Lourenço, K W Van De Kolk, Diana S. Nascimento, Jordy M. M. Kocken, Raquel Figuinha Videira, P. Mendes-Ferreira, Aida Llucià-Valldeperas, Inês Falcão-Pires
Publikováno v: Cardiovascular Research, 118(12), 2688-2702. Oxford University Press
Videira, R F, Koop, A M C, Ottaviani, L, Poels, E M, Kocken, J M M, Dos Remedios, C, Mendes-Ferreira, P, van de Kolk, K W, du Marchie Sarvaas, G J, Lourenço, A, Llucià-Valldeperas, A, Nascimento, D AS, de Windt, L J, de Man, F S, Falcão-Pires, I, Berger, R M F & da Costa Martins, P A 2022, ' The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload ', Cardiovascular Research, vol. 118, no. 12, pp. 2688-2702 . https://doi.org/10.1093/cvr/cvab299, https://doi.org/10.1093/cvr/cvab299
Aims Research on the pathophysiology of right ventricular (RV) failure has, in spite of the associated high mortality and morbidity, lagged behind compared to the left ventricle (LV).Previous work from our lab revealed that the embryonic basic helix-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca90fa70a91fff405ab555b55989501f
https://doi.org/10.1093/cvr/cvab299
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8
Interplay of sex hormones and long-term right ventricular adaptation in a Dutch PAH-cohort
Autor: Joanne A. Groeneveldt, Christophe Guignabert, Rowan Smal, Samara M.A. Jansen, Berend E. Westerhof, Peter Dorfmüller, Frances S. de Man, Frank P. T. Oosterveer, Anne Keogh, Harm Jan Bogaard, Annemieke C. Heijboer, Marie-José Goumans, Lilian J. Meijboom, Anton Vonk Noordegraaf, M. Louis Handoko, Hans W.M. Niessen, Olaf Mercier, A. Josien Smits, Cathelijne Emma van der Bruggen, Jessie Van Wezenbeek, Marc Humbert, Joost W. van Leeuwen, J. Tim Marcus, Aida Llucià-Valldeperas, Cris dos Remedios
Publikováno v: Journal of Heart and Lung Transplantation, 41(4), 445-457. Elsevier USA
Journal of heart and lung transplantation, 41(4), 445-457. Elsevier USA
The Journal of Heart and Lung Transplantation
The Journal of Heart and Lung Transplantation, 2021, Online ahead of print. ⟨10.1016/j.healun.2021.11.004⟩
Journal of Heart and Lung Transplantation. Elsevier USA
van Wezenbeek, J, Groeneveldt, JA, Llucià Valldeperas, A, van der Bruggen, CEE, Jansen, SMA, Smits, AJ, Smal, R, van Leeuwen, J W, dos Remedios, C, Keogh, A, Humbert, M, Dorfmuller, P, Mercier, O, Guignabert, C, Niessen, JWM, Handoko, ML, Marcus, JT, Meijboom, LJ, Oosterveer, F P T, Westerhof, BE, Heijboer, AC, Bogaard, HJ, Vonk-Noordegraaf, A, Goumans, M-J T H & de Man, FS 2021, ' Interplay of sex hormones and long-term right ventricular adaptation in a Dutch PAH-cohort ', Journal of Heart and Lung Transplantation . < https://www.jhltonline.org/article/S1053-2498(21)02581-X/fulltext >
van Wezenbeek, J, Groeneveldt, J A, Llucià-Valldeperas, A, van der Bruggen, C E, Jansen, S M A, Smits, A J, Smal, R, van Leeuwen, J W, Remedios, C D, Keogh, A, Humbert, M, Dorfmüller, P, Mercier, O, Guignabert, C, Niessen, H W M, Handoko, M L, Marcus, J T, Meijboom, L J, Oosterveer, F P T, Westerhof, B E, Heijboer, A C, Bogaard, H J, Noordegraaf, A V, Goumans, M J & de Man, F S 2022, ' Interplay of sex hormones and long-term right ventricular adaptation in a Dutch PAH-cohort ', Journal of Heart and Lung Transplantation, vol. 41, no. 4, pp. 445-457 . https://doi.org/10.1016/j.healun.2021.11.004
Journal of Heart and Lung Transplantation, 41(4), 445-457. ELSEVIER SCIENCE INC
BACKGROUND: To investigate the association between altered sex hormone expression and long-term right ventricular (RV) adaptation and progression of right heart failure in a Dutch cohort of Pulmonary Arterial Hypertension (PAH)-patients across a wide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4dd802a7c4895dedb51dcb85dea6d9
https://research.vumc.nl/en/publications/adf739fe-a8b8-412a-880f-03a44d45aa95
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9
The battle of new biomarkers for right heart failure in pulmonary hypertension: is the queen of hearts NT-proBNP defeated at last?
Autor: Aida Llucià-Valldeperas, Jessie Van Wezenbeek, Frances S. de Man, Marie-José Goumans
Publikováno v: Llucià-Valldeperas, A, van Wezenbeek, J, Goumans, M-J & de Man, F S 2021, ' The battle of new biomarkers for right heart failure in pulmonary hypertension : is the queen of hearts NT-proBNP defeated at last? ', The European respiratory journal, vol. 57, no. 4, 2004277 . https://doi.org/10.1183/13993003.04277-2020
The search for new biomarkers for right ventricular maladaptation in pulmonary hypertension is exciting. At this moment we are missing some key information that hampers full-scale clinical implementation.https://bit.ly/37xbgwx
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d59e699820954626459f8359db93b56
https://doi.org/10.1183/13993003.04277-2020
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10
Akademický článek
Right ventricular diastolic adaptation to pressure overload in different rat strains
Autor: Julie S. Axelsen, Stine Andersen, Steffen Ringgaard, Rowan Smal, Aida Lluciá‐Valldeperas, Jens Erik Nielsen‐Kudsk, Frances S. deMan, Asger Andersen
Publikováno v: Physiological Reports, Vol 12, Iss 13, Pp n/a-n/a (2024)
Abstract Different rat strains are used in various animal models of pulmonary hypertension and right ventricular (RV) failure. No systematic assessment has been made to test differences in RV response to pressure overload between rat strains. We comp
Externí odkaz: https://doaj.org/article/bb55993abf7c4ffabf2de252125f3bed
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