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'Alkaloids Isolated from Ephedra Alata: Characterization and Protective Effects Against Cisplatin-Induced Liver and Kidney Injuries in Mice'

Autor: Leila chekir Ghedira, Sven Mangelinckx, Eli Bonneure, Aida Lahmer, Fadwa Chaabene, Fairouz Sioud

Publikováno v: BIOMEDICAL JOURNAL OF SCIENTIFIC & TECHNICAL RESEARCH

Cisplatin (CP) is one of the most efficacious chemotherapeutic antitumor drugs. Oxidative stress has been proven to be involved in CP-induced toxicity. The aim of this study was designed to assess the protective effects of Ephedra alata alkaloids ext

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b575ed9ba9af8b2adea1c550d264d5
https://doi.org/10.26717/bjstr.2021.36.005861

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Methanolic extract of Ephedra alata ameliorates cisplatin-induced nephrotoxicity and hepatotoxicity through reducing oxidative stress and genotoxicity

Autor: Zaineb Dhaouefi, Imene Ben Toumia, Fairouz Sioud, Leila Chekir-Ghedira, Mouna Maatouk, Rihab Khlifi, Aida Lahmer, Kamel Ghedira

Publikováno v: Environmental science and pollution research international. 27(11)

Cisplatin (CP) is a powerful anticancer agent used in the treatment of a diverse type of cancers. Oxidative stress is one of the most important side effects limiting the use of cisplatin. The protective effects of methanolic extract (ME) and ephedrin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1411ce64576f554c255de6af2c3447b7
https://pubmed.ncbi.nlm.nih.gov/32008195

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