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Autor:
Verona E. Mulgrave, Abdulrahman A. Alsayegh, Aida Jaldi, DianneMarie T. Omire-Mayor, Niaya James, Oyonumo Ntekim, Eric Walters, Emanuel O. Akala, Joanne S. Allard
Publikováno v:
Neuropeptides. 97
Apolipoprotein E (ApoE) is the main cholesterol carrier of the brain and the ε4 gene variant (APOE4) is the most prevalent genetic risk factor for Alzheimer's disease (AD), increasing risk up to 15-fold. Several studies indicate that APOE4 modulates