Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Aida Iraji"'
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for hyperpigmentation. In this study,
Externí odkaz:
https://doaj.org/article/39e596d97bdb438f91c464d02ee71acc
Autor:
Aida Iraji, Parisa Nikfar, Mohammad Nazari Montazer, Mona Karimi, Najmeh Edraki, Mina Saeedi, Seyedeh Sara Mirfazli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects the elderly population globally and there is an urgent demand for developing novel anti-AD agents. In this study, a new series of indole-isoxazole carbohydra
Externí odkaz:
https://doaj.org/article/0b92848d63f94429b238c223428f7085
Autor:
Mehdi Asadi, Mohammad Mehdi Ahangari, Aida Iraji, Homa Azizian, Ali Nokhbehzaim, Saeed Bahadorikhalili, Somaye Mojtabavi, Mohamad Ali Faramarzi, Ensieh Nasli-Esfahani, Bagher Larijani, Mohammad Mahdavi, Massoud Amanlou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Α-glucosidase inhibition can be useful in the management of carbohydrate-related diseases, especially type 2 diabetes mellitus. Therefore, in this study, a new series of 6-chloro-2-methoxyacridine bearing different aryl triazole derivatives
Externí odkaz:
https://doaj.org/article/cc8866df8f404055976aafa574ebb99e
Autor:
Sama Loori, Hormoz Pourtaher, Abdolmohammad Mehranpour, Alireza Hasaninejad, Mohammadreza Eftekharian, Aida Iraji
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Alzheimer’s disease (AD), a severe neurodegenerative disorder, imposes socioeconomic burdens and necessitates innovative therapeutic strategies. Current therapeutic interventions are limited and underscore the need for novel inhibitors of
Externí odkaz:
https://doaj.org/article/4896805a41a64af1973dbc30356dc91c
Autor:
Ali Asadipour, Yaghoub Pourshojaei, Moein Mansouri, Elham Mahdavizadeh, Cambyz Irajie, Javad Mottaghipisheh, Ehsan Faghih-Mirzaei, Mohammad Mahdavi, Aida Iraji
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-18 (2024)
Abstract In this article, we present the design and synthesis of amino-7,8-dihydro-4H-chromenone derivatives as possible inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) for the management of Alzheimer’s disease (AD). The
Externí odkaz:
https://doaj.org/article/ca76def828ac46d68af872e207051eef
Autor:
Mehdi Asadi, Fahime Fayazi, Aida Iraji, Reyhaneh Sabourian, Homa Azizian, Mannan Hajimahmoodi, Bagher Larijani, Mohammad Mahdavi, Massoud Amanlou
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-12 (2024)
Abstract A novel series of 4-nitrophenylpiperazine derivatives (4a–m) was designed and synthesized as potential tyrosinase inhibitors. Comprehensive characterization using 1H-NMR, 13C-NMR, CNH, and IR techniques was performed for all target compoun
Externí odkaz:
https://doaj.org/article/31dfa5daa62b4e0fa2a560ce41de9690
Autor:
Ahmad Nazarian, Fahime Abedinifar, Haleh Hamedifar, Mohammad Hashem Hashempur, Mohammad Mahdavi, Nima Sepehri, Aida Iraji
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-15 (2024)
Abstract In pursuit of developing novel cholinesterase (ChE) inhibitors through molecular hybridization theory, a novel series of isoindolin-1,3-dione-based acetohydrazides (compounds 8a–h) was designed, synthesized, and evaluated as possible acety
Externí odkaz:
https://doaj.org/article/33e5225f8a9042abaad76b0cb3afc292
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract A novel series of kojic acid fused 2-amino-3-cyano-4H-pyran derivatives were synthesized via a multicomponent reaction involving kojic acid, benzyloxy benzaldehyde, and malonitrile as tyrosinase inhibitors. Subsequently, the structures of th
Externí odkaz:
https://doaj.org/article/33015a7db20c4ca1aef5af965c2aa023
Autor:
Alireza Askari, Fatemeh Sadat Hasheminasab, Omid Sadeghpour, Mohammad Mehdi Naghizadehd, Seyed Ali Ravansalar, Aida Iraji, Mohammad Hashem Hashempur
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundBasil is a widely used herb in Persian medicine and is gaining recognition as a functional food worldwide.Aim of the studyThis trial aimed to assess the effectiveness of a traditional formulation of basil oil in comparison with diclofenac g
Externí odkaz:
https://doaj.org/article/7ed01b49909e4d46b8bf6ea255273171
Autor:
Haleh Hamedifar, Mahroo Mirfattahi, Minoo Khalili Ghomi, Homa Azizian, Aida Iraji, Milad Noori, Ali Moazzam, Navid Dastyafteh, Ali Nokhbehzaim, Katayoun Mehrpour, Shahrzad Javanshir, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Bagher Larijani, Mir Hamed Hajimiri, Mohammad Mahdavi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Regarding the important role of α-glucosidase enzyme in the management of type 2 diabetes mellitus, the current study was established to design and synthesize aryl-quinoline-4-carbonyl hydrazone bearing different 2-methoxyphenoxyacetamide (
Externí odkaz:
https://doaj.org/article/56e2c64446dc4086a6f9ccbbd7c309c4