Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Aida I. Sacaan"'
Autor:
Aida I. Sacaan, Nasir K. Khan, Martin B. Finkelstein, Stephane Thibault, Bart A. Jessen, Tae Sung, Wenyue Hu
Supplementary references are listed for supplementary table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82650482f7204c3e6bee2eeabe11d01f
https://doi.org/10.1158/1078-0432.22460496
https://doi.org/10.1158/1078-0432.22460496
Autor:
Aida I. Sacaan, Nasir K. Khan, Martin B. Finkelstein, Stephane Thibault, Bart A. Jessen, Tae Sung, Wenyue Hu
Purpose: Palbociclib (PD-0332991) is the first selective cyclin-dependent kinase (CDK) 4/6 inhibitor approved for metastatic breast cancer. Hematologic effects, especially neutropenia, are dose-limiting adverse events for palbociclib in humans.Experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfe797ed280ffcb0fb48869aadd6981
https://doi.org/10.1158/1078-0432.c.6524514
https://doi.org/10.1158/1078-0432.c.6524514
Autor:
Aida I. Sacaan, Nasir K. Khan, Martin B. Finkelstein, Stephane Thibault, Bart A. Jessen, Tae Sung, Wenyue Hu
Supplementary Table S1-2. Table S1 - Clinical exposure for palbociclib, fulvestrant and chemotherapeutic agents used in this study. Table S2 - Cell cycle analysis in human bone marrow mononuclear cells treated with palbociclib for 4 days. Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be09a2743c601b1f49cea2592f3bfd0
https://doi.org/10.1158/1078-0432.22460502.v1
https://doi.org/10.1158/1078-0432.22460502.v1
Autor:
Aida I. Sacaan, Nasir K. Khan, Martin B. Finkelstein, Stephane Thibault, Bart A. Jessen, Tae Sung, Wenyue Hu
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10153633f952f70b4055cd6783a0d0a7
https://doi.org/10.1158/1078-0432.22460499
https://doi.org/10.1158/1078-0432.22460499
Autor:
Tadimeti S. Rao, Kevin T Whelan, R. T. Reid, P. Adams, Lucia Correa, Jean-Michel Vernier, Frederique Menzaghi, Aida I. Sacaan
Publikováno v:
Brain Research. 1003:42-53
SIB-1663 ([+/-]-7-methoxy-2,3,3a,4,5,6,9b-hexahydro-1H-pyrrolo-[3,2h]-isoquinoline) is a conformationally restricted analog of nicotine (NIC). SIB-1663 exhibited modest affinities to cholinergic receptors (K(i) values displacing the binding of [(3)H]
Publikováno v:
Brain Research. 990:203-208
Neuronal nicotinic acetylcholine receptors (nAChRs) modulate synaptic transmission by regulating neurotransmitter release, an action that involves multiple nAChRs. The effects of four nAChR agonists, nicotine (NIC), 1,1-dimethyl-4-phenylpiperzinium i
Autor:
Lucia Correa, Tadimeti S. Rao, Daniel S. Lorrain, Aida I. Sacaan, Michael F. Gardner, Emily M. Santori, R. T. Reid, Jean-Michel Vernier
Publikováno v:
Brain Research. 986:71-81
SIB-1553A ((+/-)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thiophenol HCl) is a neuronal nicotinic acetylcholine receptor (nAChR) ligand which is active in rodent and primate models of cognition. In functional assays, SIB-1553A exhibits marked subtype sele
Autor:
Lorrie P. Daggett, Peter J. Flor, J A Kerner, Rainer Kuhn, Anne B. Young, Aida I. Sacaan, David G. Standaert, F.-F. Lin, Gonul Velicelebi, C. Jachec, Mark A. Varney, Sara P. Rao
Publikováno v:
Neuropharmacology. 36:917-931
We isolated and characterized a cDNA encoding the human metabotropic glutamate receptor subtype 1b (hmGluR1b). In situ hybridization studies in human brain regions revealed a higher distribution of mGluR1 mRNA in the dentate gyrus of the hippocampus,
Publikováno v:
Synapse. 22:261-268
Projection neurons in the rat dorsolateral septal nucleus (DLSN) were retrogradely labeled following intraseptal injection of wheat germ agglutinin conjugated horseradish peroxidase (WGA-HRP). Injections of WGA-HRP centered in the medial septum (MS)
Autor:
H. Dawson, J. S. Mccallum, Ian A. McDonald, Nicholas D. P. Cosford, Kevin T Whelan, Aida I. Sacaan, Lucia Correa, Emily M. Santori, G. K. Lloyd, Jeffrey P. Whitten, R. T. Reid, Tadimeti S. Rao, A. Herbaut, Jean Michel Vernier, James H. Crona, K. A. Stauderman, L. S. Mahaffy, P. Adams, Leo Bleicher, Laura E. Chavez-Noriega, Frédérique Menzaghi
Publikováno v:
ChemInform. 27