Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Aida Habib"'
Autor:
Giovanna Petrucci, Duaa Hatem, Ruth Langley, Siobhan Cleary, Aleksandra Gentry-Maharaj, Dario Pitocco, Alessandro Rizzi, Paola Ranalli, Francesco Zaccardi, Aida Habib, Bianca Rocca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Biological samples are often frozen and stored for years and/or thawed multiple times, thus assessing their stability on long-term storage and repeated freeze–thaw cycles is crucial. The study aims were to assess:—the long-term stability
Externí odkaz:
https://doaj.org/article/d14bfbef41ca476c868bbb301c0fc4f0
Autor:
Giovanna Petrucci, Alberto Giaretta, Paola Ranalli, Viviana Cavalca, Alfredo Dragani, Benedetta Porro, Duaa Hatem, Aida Habib, Elena Tremoli, Carlo Patrono, Bianca Rocca
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 12, Pp 2958-2970 (2022)
Abstract Low‐dose aspirin is currently recommended for patients with polycythemia vera (PV), a myeloproliferative neoplasm with increased risk of arterial and venous thromboses. Based on aspirin pharmacodynamics in essential thrombocythemia, a twic
Externí odkaz:
https://doaj.org/article/2a8bd4e335b94572881af6e277d88e56
Autor:
Manon Allaire, Rola Al Sayegh, Morgane Mabire, Adel Hammoutene, Matthieu Siebert, Charles Caër, Mathilde Cadoux, JingHong Wan, Aida Habib, Maude Le Gall, Pierre de la Grange, Hervé Guillou, Catherine Postic, Valérie Paradis, Sophie Lotersztajn, Hélène Gilgenkrantz
Publikováno v:
JHEP Reports, Vol 5, Iss 8, Pp 100794- (2023)
Background & Aims: Liver regeneration is a repair process in which metabolic reprogramming of parenchymal and inflammatory cells plays a major role. Monoacylglycerol lipase (MAGL) is an ubiquitous enzyme at the crossroad between lipid metabolism and
Externí odkaz:
https://doaj.org/article/346571883a5f4eb1b52cd8a45a9591b1
Autor:
Abeer J. Ayoub, Ghewa A. El-Achkar, Sandra E. Ghayad, Layal Hariss, Razan H. Haidar, Leen M. Antar, Zahraa I. Mallah, Bassam Badran, René Grée, Ali Hachem, Eva Hamade, Aida Habib
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10399 (2023)
Benzofuran and 2,3-dihydrobenzofuran scaffolds are heterocycles of high value in medicinal chemistry and drug synthesis. Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present study, we investigat
Externí odkaz:
https://doaj.org/article/c985cd50bd2b44e585d369083ba8d7cb
Autor:
Richard Saoud, Miran A Jaffa, Aida Habib, Jingfu Zhao, Moustafa Al Hariri, Rui Zhu, Anwarul Hasan, Fuad N Ziyadeh, Firas Kobeissy, Yehia Mechref, Ayad A Jaffa
Publikováno v:
Journal of Advanced Research, Vol 24, Iss , Pp 409-422 (2020)
Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic kidney disease. Here, we
Externí odkaz:
https://doaj.org/article/75d67ff9f0c04392bbdab7a1237abdd1
Autor:
Abeer J. Ayoub, Layal Hariss, Nehme El-Hachem, Ghewa A. El-Achkar, Sandra E. Ghayad, Oula K. Dagher, Nada Borghol, René Grée, Bassam Badran, Ali Hachem, Eva Hamade, Aida Habib
Publikováno v:
BMC Chemistry, Vol 13, Iss 1, Pp 1-18 (2019)
Abstract Introduction New fluorinated diaryl ethers and bisarylic ketones were designed and evaluated for their anti-inflammatory effects in primary macrophages. Methods The synthesis of the designed molecules started from easily accessible and versa
Externí odkaz:
https://doaj.org/article/84a342bf0b0e458f804a0b73c9bae9a6
Autor:
Aneese A. Jaffa, Miran A. Jaffa, Mayssam Moussa, Ibrahim A. Ahmed, Mia Karam, Kawthar Sharaf Aldeen, Rola Al Sayegh, Ghewa A. El-Achkar, Leila Nasrallah, Yara Yehya, Aida Habib, Fuad N. Ziyadeh, Ali H. Eid, Firas H. Kobeissy, Ayad A. Jaffa
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Microglia, the resident phagocytes of the central nervous system and one of the key modulators of the innate immune system, have been shown to play a major role in brain insults. Upon activation in response to neuroinflammation, microglia promote the
Externí odkaz:
https://doaj.org/article/8dd264650da5460bb2dfd713f8d2f363
Autor:
Ibrahim A Ahmed, Miran A Jaffa, Mayssam Moussa, Duaa Hatem, Ghewa A El-Achkar, Rola Al Sayegh, Mia Karam, Eva Hamade, Aida Habib, Ayad A Jaffa
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The occurrence and persistence of hepatic injury which arises from cell death and inflammation result in liver disease. The processes that lead to liver injury progression and resolution are still not fully delineated. The plasma kallikrein-kinin sys
Externí odkaz:
https://doaj.org/article/4deb9a8e9ad54fe7a774b83a0215e5c3
Autor:
Matteo Tardelli, Francesca V. Bruschi, Thierry Claudel, Claudia D. Fuchs, Nicole Auer, Victoria Kunczer, Tatjana Stojakovic, Hubert Scharnagl, Aida Habib, Gernot F. Grabner, Robert Zimmermann, Sophie Lotersztajn, Michael Trauner
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1284-1292 (2019)
Monoacylglycerol lipase (MGL) is the rate-limiting enzyme in the degradation of monoacylglycerols. To examine the role of MGL in hepatic steatosis, WT and MGL KO (MGL−/−) mice were challenged with a Western diet (WD) over 12 weeks. Lipid metaboli
Externí odkaz:
https://doaj.org/article/02a72589b0a44e1baef87dba030ccf71
Autor:
Sonia Eligini, Susanna Colli, Aida Habib, Giancarlo Aldini, Alessandra Altomare, Cristina Banfi
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 496 (2021)
The exposure of human endothelial cells to 3-morpholinosydnonimine (SIN-1) induced the expression of cyclooxygenase-2 (COX-2) in a dose- and time-dependent manner. Interestingly, after a prolonged incubation (>8 h) several proteoforms were visualized
Externí odkaz:
https://doaj.org/article/b25dfc44a19442cb861410a864f4f455