Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Aida G Walker"'
Autor:
Takaaki Koma, Cheng Huang, Adrian Coscia, Steven Hallam, John T Manning, Junki Maruyama, Aida G Walker, Milagros Miller, Jeanon N Smith, Michael Patterson, Jonathan Abraham, Slobodan Paessler
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009356 (2021)
Several arenaviruses cause hemorrhagic fevers in humans with high case fatality rates. A vaccine named Candid#1 is available only against Junin virus (JUNV) in Argentina. Specific N-linked glycans on the arenavirus surface glycoprotein (GP) mask impo
Externí odkaz:
https://doaj.org/article/61eb758c0e974ffaae50ec79a28710df
Autor:
Takaaki Koma, Cheng Huang, Judith F Aronson, Aida G Walker, Milagros Miller, Jeanon N Smith, Michael Patterson, Slobodan Paessler
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004969 (2016)
Machupo virus (MACV), a New World arenavirus, is the etiological agent of Bolivian hemorrhagic fever (BHF). Junin virus (JUNV), a close relative, causes Argentine hemorrhagic fever (AHF). Previously, we reported that a recombinant, chimeric MACV (rMA
Externí odkaz:
https://doaj.org/article/f5db301ebd5a4384aff29339ad3888f6
Autor:
Cheng Huang, Aida G Walker, Ashley M Grant, Olga A Kolokoltsova, Nadezhda E Yun, Alexey V Seregin, Slobodan Paessler
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 6, p e2933 (2014)
The new world arenavirus Junín virus (JUNV) is the causative agent of Argentine hemorrhagic fever, a lethal human infectious disease. Adult laboratory mice are generally resistant to peripheral infection by JUNV. The mechanism underlying the mouse r
Externí odkaz:
https://doaj.org/article/e7278bae6563448b99f616d6ac767e44
Autor:
Cheng Huang, Olga A Kolokoltsova, Nadezdha E Yun, Alexey V Seregin, Allison L Poussard, Aida G Walker, Allan R Brasier, Yingxin Zhao, Bing Tian, Juan Carlos de la Torre, Slobodan Paessler
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 5, p e1659 (2012)
Junín virus (JUNV), an arenavirus, is the causative agent of Argentine hemorrhagic fever, an infectious human disease with 15-30% case fatality. The pathogenesis of AHF is still not well understood. Elevated levels of interferon and cytokines are re
Externí odkaz:
https://doaj.org/article/f483370b4ed0431aa15c643db0501333
Autor:
Michael Patterson, Jonathan Abraham, Aida G. Walker, Adrian Coscia, Cheng Huang, Milagros Miller, Slobodan Paessler, Jeanon N. Smith, John T. Manning, Takaaki Koma, Junki Maruyama, Steven Hallam
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009356 (2021)
PLoS Pathogens
PLoS Pathogens
Several arenaviruses cause hemorrhagic fevers in humans with high case fatality rates. A vaccine named Candid#1 is available only against Junin virus (JUNV) in Argentina. Specific N-linked glycans on the arenavirus surface glycoprotein (GP) mask impo
Autor:
Charles B. Chesson, Rebecca J. Nusbaum, Jagannath Chinnaswamy, Jai S. Rudra, Tara M. Clover, Matthew B. Huante, Janice J. Endsley, Aida G. Walker
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
Bacillus Calmette-Guerin (BCG) is the only vaccine against TB and has limited protection efficacy, which wanes past adolescence. Multifunctional CD8+ T cells (IFN-γ+/TNF-α+/IL-2+) are associated with lower reactivation risk and enhanced control of
Autor:
Naoki Shimizu, Rebecca S. Cook, Aida G. Walker, Shannon E. Ronca, Kelly T. Dineley, Takaaki Koma, Tomoko Makishima, Slobodan Paessler, Atsushi Tamura, Nadia Wauquier, Bayon Bockarie, Sheik Humarr Khan, Jeanon N. Smith, Joseph N. Fair, Alexey Seregin, Milagros Miller, Nadezhda E. Yun
Publikováno v:
Journal of Virology. 90:2920-2927
Approximately one-third of Lassa virus (LASV)-infected patients develop sensorineural hearing loss (SNHL) in the late stages of acute disease or in early convalescence. With 500,000 annual cases of Lassa fever (LF), LASV is a major cause of hearing l
Autor:
Steven Hallam, Takaaki Koma, Aida G. Walker, Cheng Huang, Jeanon N. Smith, Alexey Seregin, Michael Patterson, Slobodan Paessler, Payal D. Maharaj, Milagros Miller
Publikováno v:
Journal of Virology. 90:1290-1297
Machupo virus (MACV) is the causative agent of Bolivian hemorrhagic fever. Our previous study demonstrated that a MACV strain with a single amino acid substitution (F438I) in the transmembrane domain of glycoprotein is attenuated but genetically unst
Autor:
Slobodan Paessler, Alexey Seregin, Allison Poussard, Bi Hung Peng, Aida G. Walker, Jennifer S. Smith, Jenna Linde, Katherine Taylor, Milagros Salazar, Jeanon N. Smith, Michael Patterson
Publikováno v:
Vaccine. 29:9345-9351
Rapid and accurate identification of disease progression are key factors in testing novel vaccines and antivirals against encephalitic alphaviruses. Typical efficacy studies utilize a large number of animals and severe morbidity or mortality as an en
Autor:
Juan Carlos de la Torre, Aida G. Walker, Allison Poussard, Nadezhda E. Yun, Alexey Seregin, Slobodan Paessler, Sébastien Emonet
Publikováno v:
Journal of Virology. 85:1473-1483
The New World arenavirus Junin virus (JUNV) is the causative agent of Argentine hemorrhagic fever (AHF), which is associated with high morbidity and significant mortality. Several pathogenic strains of JUNV have been documented, and a highly attenuat