Výsledky vyhledávání - "Aida Abujoub"

Identification of an ADAMTS-4 Cleavage Motif Using Phage Display Leads to the Development of Fluorogenic Peptide Substrates and Reveals Matrilin-3 as a Novel Substrate

Autor: Olga V. Nemirovskiy, Marc D. Zack, Aida Abujoub, Malini Viswanathan, Anne-Marie Malfait, Joseph W. Leone, Min Liu, Richard Mazzarella, Robert L. Hills, Micky D. Tortorella, Gary J. Bassill, Arumugam Muruganandam, Elizabeth C. Arner, Kam Fok, Aaron K. Sato, Daniel J. Sexton

Publikováno v: Journal of Biological Chemistry. 282:11101-11109

ADAMTS-4 and ADAMTS-5 are aggrecanases responsible for the breakdown of cartilage aggrecan in osteoarthritis. Multiple ADAMTS-4 cleavage sites have been described in several matrix proteins including aggrecan, versican, and brevican, but no concise p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286c94e433aa96350ac059c051ba855d
https://doi.org/10.1074/jbc.m611588200

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání