Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Aida, Nourbakhsh"'
Autor:
Christine T. Dinh, Si Chen, Aida Nourbakhsh, Kyle Padgett, Perry Johnson, Stefania Goncalves, Olena Bracho, Esperanza Bas, Jorge Bohorquez, Paula V. Monje, Cristina Fernandez-Valle, Nagy Elsayyad, Xuezhong Liu, Scott M. Welford, Fred Telischi
Publikováno v:
Cancers, Vol 15, Iss 10, p 2818 (2023)
Background: Vestibular schwannomas (VS) are benign intracranial tumors caused by loss of function of the merlin tumor suppressor. We tested three hypotheses related to radiation, hearing loss (HL), and VS cell survival: (1) radiation causes HL by inj
Externí odkaz:
https://doaj.org/article/8f54a4061d454dcaabc03623c766c29e
Autor:
Aida Nourbakhsh, Nicholas C. Gosstola, Cristina Fernandez-Valle, Derek M. Dykxhoorn, Xue Zhong Liu
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102474- (2021)
The UMi031-A-2 hiPSC line contains a CRISPR-induced homozygous, Neurofibromatosis Type 2 (NF2) mutation (L64P (CTG > CCG)) in the NF2 gene that encodes a merlin tumor suppressor. This line was generated from an unaffected iPSC line using CRISPR techn
Externí odkaz:
https://doaj.org/article/4dec461c3db043138b78ad4f9361b379
Autor:
Aida Nourbakhsh, Christine T. Dinh
Publikováno v:
Otolaryngologic Clinics of North America. 56:421-434
Autor:
Christine Mei, Hongsong Dong, Eric Nisenbaum, Torin Thielhelm, Aida Nourbakhsh, Denise Yan, Molly Smeal, Yesha Lundberg, Michael E. Hoffer, Simon Angeli, Fred Telischi, Guohui Nie, Susan H. Blanton, Xuezhong Liu
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Vestibular disorders (VDs) are a clinically divergent group of conditions that stem from pathology at the level of the inner ear, vestibulocochlear nerve, or central vestibular pathway. No etiology can be identified in the majority of pat
Externí odkaz:
https://doaj.org/article/d012615d536e4cb5bf8dc13a57e26148
Autor:
Nicholas C. Gosstola, Zaohua Huang, Xiaoying Tong, Aida Nourbakhsh, Zheng-Yi Chen, Derek M. Dykxhoorn, Xue Zhong Liu
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102017- (2020)
UMi028-A-1 hiPSC line contains a CRISPR/Cas9-induced heterozygous, hearing loss-associated variant (V60L (GTA > TTA)) in the Purinergic Receptor P2X2 (P2RX2) gene. This line, derived from an unaffected male iPSC line, has been successfully characteri
Externí odkaz:
https://doaj.org/article/40d0ee6b88e94a7dad955dcb5db7417a
Autor:
Torin P. Thielhelm, Stefania Goncalves, Scott M. Welford, Eric A. Mellon, Erin R. Cohen, Aida Nourbakhsh, Cristina Fernandez-Valle, Fred Telischi, Michael E. Ivan, Christine T. Dinh
Publikováno v:
Cancers, Vol 13, Iss 18, p 4575 (2021)
Vestibular schwannomas (VS) are benign tumors arising from cranial nerve VIII that account for 8–10% of all intracranial tumors and are the most common tumors of the cerebellopontine angle. These tumors are typically managed with observation, radia
Externí odkaz:
https://doaj.org/article/13ca536338c1411c97289bd4ee78e499
Autor:
Qingling Bi, Shasha Huang, Hui Wang, Xue Gao, Minyue Ma, Mingyu Han, Sijia Lu, Dongyang Kang, Aida Nourbakhsh, Denise Yan, Susan Blanton, Xuezhong Liu, Yongyi Yuan, Yuanqing Yao, Pu Dai
Publikováno v:
Journal of Assisted Reproduction and Genetics.
Autor:
Qingling Bi, Shasha Huang, Hui Wang, Xue Gao, Minyue Ma, Mingyu Han, Sijia Lu, Dongyang Kang, Aida Nourbakhsh, Denise Yan, Susan Blanton, Xuezhong Liu, Yongyi Yuan, Yuanqing Yao, Pu Dai
Publikováno v:
Journal of Assisted Reproduction and Genetics.
Purpose To evaluate the clinical validity of preimplantation genetic testing (PGT) to prevent hereditary hearing loss (HL) in Chinese population. Methods A PGT procedure combining multiple annealing and looping-based amplification cycles (MALBAC) and
Autor:
Torin P. Thielhelm, Aida Nourbakhsh, Scott M. Welford, Eric A. Mellon, Olena Bracho, Michael E. Ivan, Fred Telischi, Cristina Fernandez‐Valle, Christine T. Dinh
Publikováno v:
Otolaryngology–Head and Neck Surgery. 167:860-868
To describe the RAD51 response (DNA repair) to radiation-induced DNA damage in patient-derived vestibular schwannoma (VS) cells and investigate the utility of RAD51 inhibitor (RI-1) in enhancing radiation toxicity.Basic and translational science.Tert
Autor:
Anita Parmigiani, Aida Nourbakhsh, Boxiao Ding, Wei Wang, Young Chul Kim, Konstantin Akopiants, Kun-Liang Guan, Michael Karin, Andrei V. Budanov
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1281-1291 (2014)
The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a sensor of different environmental conditions and regulator of cell growth, metabolism, and autophagy. mTORC1 is activated by Rag GTPases, working as RagA:RagB and RagC:RagD heterodime
Externí odkaz:
https://doaj.org/article/441d53d1e44541b9a98a2eb24af345f1