Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aici Wu"'
Autor:
Feiyue Cheng, Aici Wu, Zhihua Li, Jing Xu, Xifeng Cao, Haiying Yu, Zhenquan Liu, Rui Wang, Wenyuan Han, Hua Xiang, Ming Li
Publikováno v:
mLife, Vol 3, Iss 3, Pp 403-416 (2024)
Abstract Prokaryotic Argonautes (pAgos) provide bacteria and archaea with immunity against plasmids and viruses. Catalytically active pAgos utilize short oligonucleotides as guides to directly cleave foreign nucleic acids, while inactive pAgos lackin
Externí odkaz:
https://doaj.org/article/0c02b9fc391346bc8c30fd934e3fd3f6
Autor:
Rui Wang, Xian Shu, Huiwei Zhao, Qiong Xue, Chao Liu, Aici Wu, Feiyue Cheng, Lingyun Wang, Yihan Zhang, Jie Feng, Nannan Wu, Ming Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract CreTA, CRISPR-regulated toxin-antitoxin (TA), safeguards CRISPR-Cas immune systems by inducing cell dormancy/death upon their inactivation. Here, we characterize a bacterial CreTA associating with the I-F CRISPR-Cas in Acinetobacter. CreT is
Externí odkaz:
https://doaj.org/article/9af6f50038e3452486b995a0d6ccf7c5
Autor:
Chao Liu, Rui Wang, Jie Li, Feiyue Cheng, Xian Shu, Huiwei Zhao, Qiong Xue, Haiying Yu, Aici Wu, Lingyun Wang, Sushu Hu, Yihan Zhang, Jun Yang, Hua Xiang, Ming Li
CRISPR RNAs (crRNAs) and Cas proteins together provide prokaryotes with adaptive immunity against genetic invaders. How Cas expression is fine-tuned to avoid energy burden while satisfying the dynamic need of crRNAs remains poorly understood. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9149de9fba71e74232c63eedb810a23d
https://doi.org/10.1101/2023.03.10.532045
https://doi.org/10.1101/2023.03.10.532045
Autor:
Feiyue Cheng, Aici Wu, Chao Liu, Xifeng Cao, Rui Wang, Xian Shu, Lingyun Wang, Yihan Zhang, Hua Xiang, Ming Li
Publikováno v:
Nucleic acids research. 50(16)
Recent discovery of ectopic repeats (outside CRISPR arrays) provided unprecedented insights into the nondefense roles of CRISPR-Cas. A striking example is the addiction module CreTA (CRISPR-regulated toxin–antitoxins), where one or two (in most cas