Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Aicha Melouane"'
Publikováno v:
Metabolites, Vol 12, Iss 2, p 125 (2022)
Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein implicated in various functions, including metabolism, tissue regeneration, and functional homeostasis. SPARC/Sparc declines with ageing but increases with exercise.
Externí odkaz:
https://doaj.org/article/6eac9c2334664d06a79db1dc7cb168ac
Autor:
Octave Mucunguzi, Aicha Melouane, Abdelaziz Ghanemi, Mayumi Yoshioka, André Boivin, Ezequiel-Luis Calvo, Jonny St-Amand
Publikováno v:
Nutrition & Metabolism, Vol 14, Iss 1, Pp 1-10 (2017)
Abstract Background High-fat (HF) diet is a well-known cause of obesity. To identify principle transcriptional regulators that could be therapeutic targets of obesity, we investigated transcriptomic modulation in the duodenal mucosa following low-fat
Externí odkaz:
https://doaj.org/article/11a9bfc0e9e7420f8ebbc563078aac8a
Publikováno v:
Applied Sciences, Vol 10, Iss 24, p 9108 (2020)
We previously identified secreted protein acidic and rich in cysteine (Sparc) as an exercise-induced gene in young and elderly individuals. Via this animal experiment, we aim to identify selected implications of SPARC mainly within the muscle in the
Externí odkaz:
https://doaj.org/article/f4e4b5f17e2d4881bbbda1b0c69b5036
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192714 (2018)
Secreted protein, acidic and rich in cysteine (SPARC) is differentially associated with cell proliferation and extracellular matrix (ECM) assembly. We show here the effect of exogenous SPARC inhibition/induction on ECM and mitochondrial proteins expr
Externí odkaz:
https://doaj.org/article/437c3b188a8a43e8ae2fa04517fe6659
Publikováno v:
Life Sciences. 229:277-287
Aims Secreted protein acidic and rich in cysteine, (SPARC), is a matricellular protein implicated in the modulation of the extracellular matrix (ECM) and mitochondrial proteins expression. Main methods To study the mechanism through which SPARC is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7256e18e7b18a9a7e9cb7f4abf7e7de8
https://doi.org/10.1016/j.lfs.2019.05.070
https://doi.org/10.1016/j.lfs.2019.05.070
Publikováno v:
Life Sciences. 215:190-197
Aims Trefoil factor family member 2 (TFF2) is a small gut peptide. We have previously shown that Tff2 knock out (KO) mice are protected from high-fat (HF) diet-induced obesity (De Giorgio et al., 2013a). Thus, exploring Tff2 KO-related pathways of mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a71d5c56fd4b7fb723e9d71d525ffc
https://doi.org/10.1016/j.lfs.2018.11.006
https://doi.org/10.1016/j.lfs.2018.11.006
Publikováno v:
Applied Sciences, Vol 10, Iss 9108, p 9108 (2020)
Applied Sciences
Volume 10
Issue 24
Applied Sciences
Volume 10
Issue 24
We previously identified secreted protein acidic and rich in cysteine (Sparc) as an exercise-induced gene in young and elderly individuals. Via this animal experiment, we aim to identify selected implications of SPARC mainly within the muscle in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf073ae5eea5d21640a694825de660c
https://www.mdpi.com/2076-3417/10/24/9108
https://www.mdpi.com/2076-3417/10/24/9108
Publikováno v:
Genes, Vol 11, Iss 875, p 875 (2020)
Genes
Genes
The heavy impact of obesity on both the population general health and the economy makes clarifying the underlying mechanisms, identifying pharmacological targets, and developing efficient therapies for obesity of high importance. The main struggle fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ecd182e4265c53a54dc53729b6b35b
https://www.mdpi.com/2073-4425/11/8/875
https://www.mdpi.com/2073-4425/11/8/875
Publikováno v:
Ageing Research Reviews. 41:53-63
Identifying therapeutic target genes represents the key step in functional genomics-based therapies. Within this context, the disease heterogeneity, the exogenous factors and the complexity of genomic structure and function represent important challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d968747cf98da27074b7be7b68f832e3
https://doi.org/10.1016/j.arr.2017.10.006
https://doi.org/10.1016/j.arr.2017.10.006
Publikováno v:
Mitochondrion. 50
Sarcopenia is a geriatric syndrome characterized by a progressive and generalized loss of muscle mass, strength, and endurance. Although the mitochondrial hypothesis of sarcopenia has been proposed, it remains a highly debated topic. The age-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29d512f97c1764de0a1b1b9d7da64ab
https://pubmed.ncbi.nlm.nih.gov/31669412
https://pubmed.ncbi.nlm.nih.gov/31669412