Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Aicha Laghmouchi"'
1
Akademický článek
Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity
Autor: Aicha Laghmouchi, Michel G. D. Kester, Conny Hoogstraten, Lois Hageman, Wendy de Klerk, Wesley Huisman, Eva A. S. Koster, Arnoud H. de Ru, Peter van Balen, Sebastian Klobuch, Peter A. van Veelen, J. H. Frederik Falkenburg, Inge Jedema
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
In the context of HLA-DP-mismatched allogeneic stem cell transplantation, mismatched HLA-DP alleles can provoke profound allo-HLA-DP-specific immune responses from the donor T-cell repertoire leading to graft-versus-leukemia effect and/or graft-versu
Externí odkaz: https://doaj.org/article/d97ad938d6f94d7bbb24d680cfd08676
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2
Akademický článek
Emerging Concepts in Immune Thrombotic Thrombocytopenic Purpura
Autor: Aicha Laghmouchi, Nuno A. G. Graça, Jan Voorberg
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Immune thrombotic thrombocytopenic purpura (iTTP) is an autoimmune disorder of which the etiology is not fully understood. Autoantibodies targeting ADAMTS13 in iTTP patients have extensively been studied, the immunological mechanisms leading to the b
Externí odkaz: https://doaj.org/article/60f39ee536b34888bd6fb970198502b0
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3
Akademický článek
The allogeneic HLA-DP-restricted T-cell repertoire provoked by allogeneic dendritic cells contains T cells that show restricted recognition of hematopoietic cells including primary malignant cells
Autor: Aicha Laghmouchi, Conny Hoogstraten, Peter van Balen, J.H. Frederik Falkenburg, Inge Jedema
Publikováno v: Haematologica, Vol 104, Iss 1 (2019)
Stem cell grafts from 10/10 HLA-matched unrelated donors are often mismatched for HLA-DP. In some patients, donor T-cell responses targeting the mismatched HLA-DP allele(s) have been found to induce a specific graft-versus-leukemia effect without coi
Externí odkaz: https://doaj.org/article/f8d4afc4a3294f0cb788dbbd056b3d66
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4
Emerging Concepts in Immune Thrombotic Thrombocytopenic Purpura
Autor: Jan Voorberg, Aicha Laghmouchi, Nuno A. G. Graça
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Immune thrombotic thrombocytopenic purpura (iTTP) is an autoimmune disorder of which the etiology is not fully understood. Autoantibodies targeting ADAMTS13 in iTTP patients have extensively been studied, the immunological mechanisms leading to the b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a276b22bb8ebe72e2a6899bc8ac9a5
https://www.frontiersin.org/articles/10.3389/fimmu.2021.757192/full
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5
Long-term in vitro persistence of magnetic properties after magnetic bead-based cell separation of T cells
Autor: Conny Hoogstraten, Aicha Laghmouchi, J. H. Frederik Falkenburg, I. Jedema
Publikováno v: Scandinavian Journal of Immunology, 92(3). WILEY
Scandinavian Journal of Immunology
Magnetic‐activated cell sorting (MACS) using magnetic nanoparticles coated with specific antibodies is commonly used in immunology research. For in vitro isolation purposes, it is important to know to what extent the magnetic properties remain pres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2048e787fb5d793d95332bd302f77021
http://hdl.handle.net/1887/3185136
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6
Priming of allo-HLA-DP-specific reactivity from the naive T cell compartment is not exclusively mediated by professional antigen-presenting cells
Autor: Aicha Laghmouchi, J.H. Frederik Falkenburg, Inge Jedema, Conny Hoogstraten
Publikováno v: Biology of Blood and Marrow Transplantation, 26(7), 1257-1265. ELSEVIER SCIENCE INC
Allogeneic (allo) stem cell transplantation is applied to patients suffering from hematologic malignancies to replace the diseased hematopoietic system with cells derived from a donor stem cell graft. The majority of 10/10matched unrelated donors are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3e717a3750cc486cd69f2a5f51fbe4
https://hdl.handle.net/1887/3185137
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7
The allogeneic HLA-DP-restricted T-cell repertoire provoked by allogeneic dendritic cells contains T cells that show restricted recognition of hematopoietic cells including primary malignant cells
Autor: Peter van Balen, Aicha Laghmouchi, Conny Hoogstraten, J.H. Frederik Falkenburg, Inge Jedema
Publikováno v: Haematologica, 104(1), 197-206
Haematologica
Stem cell grafts from 10/10 HLA-matched unrelated donors are often mismatched for HLA-DP. In some patients, donor T-cell responses targeting the mismatched HLA-DP allele(s) have been found to induce a specific graft-versus-leukemia effect without coi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ff90b5bc7316a1757b099a1698599c
https://doi.org/10.3324/haematol.2018.193680
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8
The Allo-HLA-DP Restricted T Cell Repertoire Contains a Variety of Tissue-Restricted Specificities with Therapeutic Value
Autor: Conny Hoogstraten, Peter van Balen, Inge Jedema, Aicha Laghmouchi, Rick van de Water, Marian van de Meent, J.H. Frederik Falkenburg
Publikováno v: Blood. 128:3356-3356
T cell-depleted allogeneic stem cell transplantation (alloSCT) is applied in patients with hematological malignancies to reduce the risk of graft versus host disease (GvHD), but the associated increased risk of infections and disease relapse makes sc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8da7f8010a2e31a6a67a809174aa019c
https://doi.org/10.1182/blood.v128.22.3356.3356
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