NOVEL COMPOSITES OF POLY(L-LACTIDE) AND SURFACE MODIFIED BIOACTIVE SiO2-CAO-P2O5 GEL NANOPARTICLES:: MECHANICAL AND BIOLOGICAL PROPERTIES.

Autor: Ai-xue Liu^1,2, Jun-chao Wei^1,2, Xue-si Chen^1,2 xschen@ciac.jl.cn, Xia-bin Jing^1,2, Yang Cui³, Yi Liu³

Publikováno v: Chinese Journal of Polymer Science (World Scientific Publishing Company). May2009, Vol. 27 Issue 3, p415-426. 12p. 1 Black and White Photograph, 3 Diagrams, 7 Graphs.

RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

Autor: George J. Cerniglia, Ai-xue Liu, Eric J. Bernhard, George C. Prendergast

Publikováno v: Proceedings of the National Academy of Sciences. 98:6192-6197

The effect of neoplastic transformation on the response to genotoxic stress is of significant clinical interest. In this study, we offer genetic evidence that the apoptotic response of neoplastically transformed cells to DNA damage requires RhoB, a m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9d037a2b30ed1a1b2af7e27ab46c7b
https://doi.org/10.1073/pnas.111137198

The effect of antisense epidermal growth factor receptor (EGFR) RNA on the proliferation of human glioma cells and induction of cell apoptosis

Autor: Chun-yan Wang, Pei-yu Pu, Guang-xiu Wang, Ai-xue Liu, Xu-wen Liu

Publikováno v: Chinese Journal of Cancer Research. 11:164-168

Objective: To study the effect of antisense EGFR RNA on the growth of human glioma cells in vitro and evaluate the feasibility of targeting EGFR gene for gene therapy of gliomas. Methods: Southern and Northern blot analysis, in situ hybridization and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6a90d967664856916ed393cabe16015
https://doi.org/10.1007/s11670-999-0003-1

Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1

Autor: George C. Prendergast, Judith F. Baker, Wei Du, James B. DuHadaway, Alexander J. Muller, Diane M Sharp, Scott Donover, Ai–xue Liu

Publikováno v: Oncogene. 22(23)

Neoplastic transformation sensitizes many cells to apoptosis. This phenomenon may underlie the therapeutic benefit of many anticancer drugs, but its molecular basis is poorly understood. We have used a selective and potent farnesyltransferase inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1c130a4291d71f5c85e78c393c349d
https://pubmed.ncbi.nlm.nih.gov/12789266

RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage.

Autor: Ai-xue Liu, Cerniglia, George J., Bernhard, Eric J., Prendergast, George C.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 05/22/2001, Vol. 98 Issue 11, p6192, 6p, 2 Black and White Photographs, 2 Diagrams, 9 Graphs