Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ai-shen Gong"'
Autor:
Lei Zhang, Peng Cho Tang, Dan Dan Si, Jing Jing Luo, Zhi Gang Lin, Ai Shen Gong, Yang Wang, Gao Hong She, Jian Hong Fu, Jun Dai, Qian Wang, Fang Long Yang, Jun Feng
Publikováno v:
Chinese Chemical Letters. 21:253-256
An efficient stereoselective synthesis of the rigid aza-bicyclo[3.2.0]heptane scaffold has been developed to provide 2-cyano pyrrolidine alpha-amino amide 1 as DPP-4 inhibitor.
Publikováno v:
Acta Pharmacologica Sinica. 27:506-512
Aim: Imrecoxib is a novel and moderately selective COX-2 inhibitor. The aim of the present in vitro investigation was to study the formation of the major metabolite 4'-carboxylic acid imrecoxib (M2) and identify the enzyme(s) involved in the reaction
Autor:
Hai-Yan, Xu, Peng, Zhang, Ai-Shen, Gong, Yu-Ming, Sun, Feng-Ming, Chu, Zong-Ru, Guo, Da-Fang, Zhong
Publikováno v:
Acta pharmacologica Sinica. 27(4)
Imrecoxib is a novel and moderately selective COX-2 inhibitor. The aim of the present in vitro investigation was to study the formation of the major metabolite 4'-carboxylic acid imrecoxib (M2) and identify the enzyme(s) involved in the reaction.The