Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ai-fu Lin"'
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011222 (2023)
Endogenous retroviruses (ERVs) are the relics of ancient retroviruses occupying a substantial fraction of vertebrate genomes. However, knowledge about the functional association of ERVs with cellular activities remains limited. Recently, we have iden
Externí odkaz:
https://doaj.org/article/d040c6ef6dd848c0938f80b11b0b9d04
Autor:
Yuan-hui Li, Shuang Shen, Tong Shao, Meng-ting Jin, Dong-dong Fan, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Mesenchymal stem cell (MSC) therapy has become a promising treatment for liver fibrosis due to its predominant immunomodulatory performance in hepatic stellate cell inhibition and fibrosis resolution. However, the cellular and molecular mech
Externí odkaz:
https://doaj.org/article/b1a717fc229c4d82b88e4c6d4a3e5077
Autor:
Ning Su, Chong-bin Hu, Tong Shao, Chun-yu Jin, Hao Li, Jian-fei Ji, Lu-lu Qin, Dong-Dong Fan, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao
Publikováno v:
Fish and Shellfish Immunology Reports, Vol 2, Iss , Pp 100038- (2021)
CD40 and CD154 are one of the best-characterized costimulatory molecules essential for adaptive immunity, which extensively involved in T and B cell activation, IgM Ab production, isotype class switching, germinal center formation and affinity matura
Externí odkaz:
https://doaj.org/article/633b795073464be594dcb17b8416ba31
Autor:
Jun Bai, Zuo-zhen Yang, Hao Li, Yun Hong, Dong-dong Fan, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Endogenous retroviruses (ERVs) occupy a substantial fraction of mammalian genomes. However, whether ERVs extensively exist in ancient vertebrates remains unexplored. Here, we performed a genome-wide characterization of ERVs in a zebrafish (D
Externí odkaz:
https://doaj.org/article/6742fac91b6d4281b84dbc173569c437
Autor:
Huai-ping Tang, Chen Huang, Chong-bin Hu, Hao Li, Tong Shao, Jian-fei Ji, Jun Bai, Dong-dong Fan, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The Toll/interleukin-1 receptor (TIR) domain is a structural unit responsible for the assembly of signal protein complexes in Toll-like receptor (TLR) and interleukin-1 receptor signaling pathways. TIR domain homologs are found in a considerable numb
Externí odkaz:
https://doaj.org/article/126353bbc4884b9891999865f05f4a94
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Hepcidin acts as both an antimicrobial peptide and a hormonal regulator of iron homeostasis; however, the biological significance of this dual-function in immune reactions remains elusive. In this study, we provide experimental evidence rega
Externí odkaz:
https://doaj.org/article/d19dc6f129d944dba317e0a499802479
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
DDX41 is an important sensor for host recognition of DNA viruses and initiation of nuclear factor-κB (NF-κB) and IFN signaling pathways in mammals. However, its occurrence and functions in other vertebrates remain poorly defined. Here, a DDX41 orth
Externí odkaz:
https://doaj.org/article/e158fdc5cbb349f1969c62dfb1da8efc
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD58 and CD2 have long been known as a pair of reciprocal adhesion molecules involved in the immune modulations of CD8+ T and NK-mediated cellular immunity in humans and several other mammals. However, the functional roles of CD58 and CD2 in CD4+ T-m
Externí odkaz:
https://doaj.org/article/c5a7d49948ea484f8b51f4aa105ea492
Autor:
Chong‐Bin Hu, Jie Wang, Yun Hong, Hao Li, Dong‐Dong Fan, Ai‐Fu Lin, Li‐Xin Xiang, Jian‐Zhong Shao
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af780c860983891dc8cd99ba26afb60
https://doi.org/10.1096/fj.202201505rrrr
https://doi.org/10.1096/fj.202201505rrrr
Autor:
Tong Shao, Jian-fei Ji, Jia-yu Zheng, Chen Li, Lv-yun Zhu, Dong-Dong Fan, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao
Publikováno v:
The Journal of Immunology. 208:2686-2701
The establishment of an appropriate costimulatory phenotype is crucial for dendritic cells (DCs) to maintain a homeostatic state with optimal immune surveillance and immunogenic activities. The upregulation of CD80/86 and CD40 is a hallmark costimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3cfd6bfd5179fe2ed73385ed434a27f
https://doi.org/10.4049/jimmunol.2100952
https://doi.org/10.4049/jimmunol.2100952