Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ai-Xin Song"'
Autor:
Wen-Tian He, Xue-Ming Zheng, Yu-Hang Zhang, Yong-Guang Gao, Ai-Xin Song, Françoise Gisou van der Goot, Hong-Yu Hu
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147515 (2016)
Ubiquitin-specific protease 19 (USP19) is one of the deubiquitinating enzymes (DUBs) involved in regulating the ubiquitination status of substrate proteins. There are two major isoforms of USP19 with distinct C-termini; the USP19_a isoform has a tran
Externí odkaz:
https://doaj.org/article/f2c7b2513a864578a28af04f68ff4cc7
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107509 (2014)
The ubiquitination levels of protein substrates in eukaryotic cells are delicately orchestrated by various protein cofactors and enzymes. Dendritic cell-derived ubiquitin (Ub)-like protein (DC-UbP), also named as Ub domain-containing protein 2 (UBTD2
Externí odkaz:
https://doaj.org/article/fa35e5129f4d4f85a5042793cb1dc9b0
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29362 (2011)
Deubiquitination is a reverse process of cellular ubiquitination important for many biological events. Ubiquitin (Ub)-specific protease 13 (USP13) is an ortholog of USP5 implicated in catalyzing hydrolysis of various Ub chains, but its enzymatic prop
Externí odkaz:
https://doaj.org/article/e7ba21f7e02e4864a69f4ac9d865e33b
Autor:
Xue-Chao Gao, Chen-Jie Zhou, Zi-Ren Zhou, Yu-Hang Zhang, Xue-Ming Zheng, Ai-Xin Song, Hong-Yu Hu
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19763 (2011)
Homo sapiens J domain protein (HSJ1) is a J-domain containing co-chaperone that is known to stimulate ATPase activity of HSP70 chaperone, while it also harbors two ubiquitin (Ub)-interacting motifs (UIMs) that may bind with ubiquitinated substrates a
Externí odkaz:
https://doaj.org/article/cf325139065c4d9896fad4999e4a6941
Autor:
Ai-Xin Song, Chen-Jie Zhou, Yu Peng, Xue-Chao Gao, Zi-Ren Zhou, Qing-Shan Fu, Jing Hong, Dong-Hai Lin, Hong-Yu Hu
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13202 (2010)
The ubiquitin-interacting motif (UIM) is a short peptide with dual function of binding ubiquitin (Ub) and promoting ubiquitination. We elucidated the structures and dynamics of the tandem UIMs of ataxin-3 (AT3-UIM12) both in free and Ub-bound forms.
Externí odkaz:
https://doaj.org/article/525e245ed1ff41f288a5e28f697b6b28
Autor:
Donghai Lin, Xiao Jing Lin, Yong-Gang Chang, Yong-Guang Gao, Xuetao Cao, Ai Xin Song, Hong-Yu Hu, Yan Hong Shi
Publikováno v:
Protein Science. 15:1248-1259
Ubiquitin is an important cellular signal that targets proteins for degradation or regulates their functions. The previously identified BMSC-UbP protein derived from bone marrow stromal cells contains a ubiquitin-associated (UBA) domain at the C term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9012271c837f28a188ceacb04749a1
https://doi.org/10.1110/ps.051995006
https://doi.org/10.1110/ps.051995006
Autor:
Yan-Hong Shi, Hong-Yu Hu, Ai-Xin Song, Xuetao Cao, Yong-Gang Chang, Donghai Lin, Yi-Zi Yu, Shuxun Liu, Yong-Guang Gao
Publikováno v:
Protein Science. 14:2044-2050
The previously identified dendritic cell-derived ubiquitin-like protein (DC-UbP) was implicated in cellular differentiation and apoptosis. Sequence alignment suggested that it contains a ubiquitin-like (UbL) domain in the C terminus. Here, we present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bab1b4525e8efd6a5c039b27858a85
https://doi.org/10.1110/ps.051455505
https://doi.org/10.1110/ps.051455505
Autor:
Xiao Jing Lin, Yong-Guang Gao, Donghai Lin, Qiu Hua Hang, Ai Xin Song, Yong-Gang Chang, Yan Hong Shi, Hong-Yu Hu
Publikováno v:
Protein Expression and Purification. 42:146-152
HSPC144 is a newly identified gene in human CD34(+) hematopoietic stem/progenitor cells, In this work. we have expressed and purified the 225-residue protein from Escherichia coli BL21 (DE3) and identified a stable fragment HSPC144-P (residues 44 225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d5bc60478c02987737ed50a6f188bf
https://doi.org/10.1016/j.pep.2005.03.008
https://doi.org/10.1016/j.pep.2005.03.008
Publikováno v:
Journal of the Chinese Chemical Society. 51:629-636
A new biflavonoid glucoside, apigenin-7-O-β-D-glucopyranoside-(3′-O-7″)-quercetin-3″-methyl ether (1) together with twenty known compounds, apigenin (2), luteolin (3), chrysoeriol (4), tricin (5), hispidulin (6), pectolinarigenin (7), eupatili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01361cf02c6df2fabd5fc76938e9c760
https://doi.org/10.1002/jccs.200400094
https://doi.org/10.1002/jccs.200400094
Publikováno v:
Protein Engineering Design and Selection. 16:435-441
To investigate the contribution of tryptophan-121 (Trp121) residue to the structure and function of soluble Cu A domain of cytochrome c oxidase, three mutant proteins, Trp121Tyr, Trp121Leu and Trp121-deleted mutant of thesoluble domain of Paracoccus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd29b4f432db9e9b097b1acbe88df47b
https://doi.org/10.1093/protein/gzg059
https://doi.org/10.1093/protein/gzg059