Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ai-Niu Ma"'
Autor:
Hong Wei, Hui Fan, Hai-Yun Wu, Teng-Fei Li, Ai-Niu Ma, Antti Pertovaara, Xin-Yan Li, Yong-Xiang Wang
Publikováno v:
Pharmacological Reports. 68:472-475
Background Prolonged morphine treatment leads to antinociceptive tolerance. Suppression of spinal astrocytes or d -amino acid oxidase (DAAO), an astroglial enzyme catalyzing oxidation of d -amino acids, has reversed morphine antinociceptive tolerance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e240913ace0979dfb21fecdee7bb343
https://doi.org/10.1016/j.pharep.2015.11.008
https://doi.org/10.1016/j.pharep.2015.11.008
Publikováno v:
British Journal of Pharmacology. 172:64-79
Background and Purpose Two peptide agonists of the glucagon-like peptide-1 (GLP-1) receptor, exenatide and GLP-1 itself, exert anti-hypersensitive effects in neuropathic, cancer and diabetic pain. In this study, we have assessed the anti-allodynic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36f2cce918dc43dcbb84a2f7723f1084
https://doi.org/10.1111/bph.12895
https://doi.org/10.1111/bph.12895
Publikováno v:
Neuropharmacology. 84:31-45
We recently discovered that the activation of the spinal glucagon-like peptide-1 receptors (GLP-1Rs) by the peptidic agonist exenatide produced antinociception in chronic pain. We suggested that the spinal GLP-1Rs are a potential target molecule for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ea0398374a15ec043e07a4f5561352
https://doi.org/10.1016/j.neuropharm.2014.04.007
https://doi.org/10.1016/j.neuropharm.2014.04.007
Autor:
Ai-Niu Ma, Antti Pertovaara, Jin-Lu Huang, Xin-Yan Li, Hong Wei, Yong-Xiang Wang, Hui Fan, Nian Gong
Publikováno v:
Pharmacology Biochemistry and Behavior. 111:30-36
We studied the hypothesis that spinal d-amino acid oxidase (DAAO) that is expressed in astrocytes and that has been reported to promote tonic pain in various pathophysiological conditions plays a role in 'physiological' pain hypersensitivity induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7087bc73f3ff583aa85da96f1e0e3462
https://doi.org/10.1016/j.pbb.2013.08.003
https://doi.org/10.1016/j.pbb.2013.08.003
Autor:
Hai-Yun Wu, Teng-Fei Li, Yong-Xiang Wang, Ai-Niu Ma, Xiao-Fang Mao, Xin-Yan Li, Antti Pertovaara, Hong Wei, Zuyue Chen
Spinal transient receptor potential ankyrin 1 (TRPA1) channel is associated with various pain hypersensitivity conditions. Spinally, TRPA1 is expressed by central terminals of nociceptive nerve fibers and astrocytes. Among potential endogenous agonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9db9be7d1c578018d88ca27f1248f2
http://hdl.handle.net/10138/231311
http://hdl.handle.net/10138/231311
Autor:
Xuebing Xu, Wei Luo, Liangli Lucy Yu, Haiming Shi, Fang Qin, Man Liu, Boyan Gao, Ping-Ping Wu, Ai-Niu Ma, Yuan-Rong Jiang
Publikováno v:
Food and Chemical Toxicology. 50:3785-3791
The acute oral toxicity of 1-palmitoyl-3-chloropropanediol (3-MCPD 1-monopalmitate) and 1,2-bis-palmitoyl-3-chloropropanediol (3-MCPD dipalmitate) in Swiss mice were examined, along with their cytotoxicity in NRK-52E rat kidney cells. LD50 (median le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec94b155977426e4b7c79a968e632a7
https://doi.org/10.1016/j.fct.2012.07.038
https://doi.org/10.1016/j.fct.2012.07.038
Publikováno v:
Neuropharmacology. 63:460-468
A series of experiments using technologies of gene mutation and silencing as well as chemical biology have demonstrated that spinal D-amino acid oxidase (DAAO) contributes to the development of central sensitization-mediated chronic pain and might be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9bbb6592c20211b1c7b2c29025add7
https://doi.org/10.1016/j.neuropharm.2012.04.030
https://doi.org/10.1016/j.neuropharm.2012.04.030
Autor:
Xin-Yan Li, Antti Pertovaara, Hong Wei, Yong-Xiang Wang, Bin Hao, Yan-Chao Wang, Jin-Lu Huang, Ai-Niu Ma, Gong Nian
Publikováno v:
Scandinavian Journal of Pain. 2:64-69
Background Sleep deprivation as well as peripheral neuropathy and cutaneous neurogenic inflammation has a facilitatory effect on pain perception. Here we studied whether oxidative stress-related mechanisms in the spinal cord that have been shown to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f013b495098f50069b85ead03550f1a3
https://doi.org/10.1016/j.sjpain.2011.01.001
https://doi.org/10.1016/j.sjpain.2011.01.001
Publikováno v:
Biochemical and Biophysical Research Communications. 404:268-272
DNA methylation and histone acetylation are major epigenetic modifications in gene silencing. In our previous research, we found that the methylated oligonucleotide (SurKex) complementary to a region of promoter of survivin could induce DNA methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fbef1f571e9aa679fb7886a40e56ed
https://doi.org/10.1016/j.bbrc.2010.11.105
https://doi.org/10.1016/j.bbrc.2010.11.105
Publikováno v:
Pharmacology Biochemistry and Behavior. 97:377-383
We studied the hypothesis that some of the spinal mechanisms that are involved in neuropathic hypersensitivity play a role in hypersensitivity induced by REM sleep deprivation (REMSD). Rats with a chronic intrathecal (i.t.) catheter had REMSD of 48 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3e133ec705ee73f36da4e7c5cf25bc
https://doi.org/10.1016/j.pbb.2010.09.007
https://doi.org/10.1016/j.pbb.2010.09.007