Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Ai-Li Shiau"'
Publikováno v:
Veterinary Quarterly, Vol 43, Iss 1, Pp 1-9 (2023)
AbstractBackground Cyclic peptide nanotubes (cPNTs) formed from the spontaneous beta-sheet stacking of peptide rings may serve as a safe and effective oral delivery vehicle/adjuvant for DNA vaccines.Aim In this study, we sought to determine if a DNA
Externí odkaz:
https://doaj.org/article/b0a33d35cefe46a5b411bce302120fb7
Autor:
Shih-Yao Chen, Chung-Teng Wang, Tang-Hsiu Huang, Jeng-Liang Tsai, Hao-Tien Wang, Yi-Ting Yen, Yau-Lin Tseng, Chao-Liang Wu, Jia-Ming Chang, Ai-Li Shiau
Publikováno v:
Cells, Vol 13, Iss 18, p 1597 (2024)
Lung cancer remains a formidable health challenge due to its high mortality and morbidity rates. Non-small cell lung cancer (NSCLC) constitutes approximately 85% of all lung cancer cases, with small cell lung cancer (SCLC) accounting for the remainde
Externí odkaz:
https://doaj.org/article/168b9edf4b8c44bfb117acb81587615b
Autor:
Mei-Lin Yang, Chia-Ling Lin, Yi-Cheng Chen, I-An Lu, Bing-Hua Su, Yen-Hsu Chen, Kuan-Ting Liu, Chao-Liang Wu, Ai-Li Shiau
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108422- (2024)
Summary: Thrombocytopenia is the hallmark finding in dengue virus (DENV) infection. Prothymosin α (ProT) has both intracellular and extracellular functions involved in cell cycle progression, cell differentiation, gene regulation, oxidative stress r
Externí odkaz:
https://doaj.org/article/1f46d4b334e64a60abd6957a2e4e9c1e
Autor:
Shih-Yao Chen, Chuan-Yin Fang, Bing-Hwa Su, Hao-Ming Chen, Shih-Chi Huang, Po-Ting Wu, Ai-Li Shiau, Chao-Liang Wu
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 780 (2024)
Inflammatory bowel disease (IBD) is an inflammatory condition affecting the colon and small intestine, with Crohn’s disease and ulcerative colitis being the major types. Individuals with long-term IBD are at an increased risk of developing colorect
Externí odkaz:
https://doaj.org/article/498343e7c9f1433484f5ee2827ab2155
Autor:
Mei-Lin Yang, Yi-Cheng Chen, Chung-Teng Wang, Hao-Earn Chong, Nai-Hui Chung, Chia-Hsing Leu, Fu-Tong Liu, Michael M. C. Lai, Pin Ling, Chao-Liang Wu, Ai-Li Shiau
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-22 (2023)
Abstract Background Influenza is one of the most important viral infections globally. Viral RNA-dependent RNA polymerase (RdRp) consists of the PA, PB1, and PB2 subunits, and the amino acid residues of each subunit are highly conserved among influenz
Externí odkaz:
https://doaj.org/article/8201530a06c646baba7c06ffdd648f2d
Autor:
Che-Yuan Hu, Bing-Hua Su, Ya-Che Lee, Chung-Teng Wang, Mei-Lin Yang, Wan-Ting Shen, Jing-Ting Fu, Shih-Yao Chen, Wei-Yun Huang, Chien-Hui Ou, Yuh-Shyan Tsai, Feng-Chih Kuo, Ai-Li Shiau, Gia-Shing Shieh, Chao-Liang Wu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-23 (2022)
Abstract Background Cisplatin-based chemotherapy is the first line of treatment for bladder cancer. However, cisplatin induces muscle wasting associated with NF-κB and cancer cachexia. HOTAIR, an oncogenic long non-coding RNA (lncRNA), promotes canc
Externí odkaz:
https://doaj.org/article/2d9188e654d54209b396a864538e2343
Autor:
Yu-Tung Hsieh, Yu-Chi Chou, Pin-Yu Kuo, Hung-Wen Tsai, Yi-Ting Yen, Ai-Li Shiau, Chrong-Reen Wang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background Increasing evidences have suggested an important role of microRNAs (miRNAs) in regulating cell death processes including NETosis and apoptosis. Dysregulated expression of miRNAs and increased formation of neutrophil extracellular
Externí odkaz:
https://doaj.org/article/babdda5bc276451696edc1a0386719a8
Autor:
Che-Yuan Hu, Chi-Feng Hung, Pi-Che Chen, Jia-Yu Hsu, Chung-Teng Wang, Ming-Derg Lai, Yuh-Shyan Tsai, Ai-Li Shiau, Gia-Shing Shieh, Chao-Liang Wu
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2598 (2023)
Immunotherapy has emerged as a promising modality for cancer treatment. Dendritic cell immunoreceptor (DCIR), a C-type lectin receptor, is expressed mainly by dendritic cells (DCs) and mediates inhibitory intracellular signaling. Inhibition of DCIR a
Externí odkaz:
https://doaj.org/article/3d33ad029c674c0685ee1e0eeb188d69
Autor:
Chun-Yang Lin, Meng-Cen Shih, Hung-Chun Chang, Kuan-Jung Lin, Lin-Fang Chen, Sheng-Wen Huang, Mei-Lin Yang, Sheng-Kai Ma, Ai-Li Shiau, Jen-Ren Wang, Kuan-Ru Chen, Pin Ling
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Abstract Background Influenza A virus (IAV) evolves strategies to counteract the host antiviral defense for establishing infection. The influenza A virus (IAV) non-structural protein 1 (NS1) is a key viral factor shown to counteract type I IFN antivi
Externí odkaz:
https://doaj.org/article/4827f4362e954f52bfff9b535da06807
Autor:
Shih-Yao Chen, Chun-Ting Chu, Mei-Lin Yang, Jian-Da Lin, Chung-Teng Wang, Che-Hsin Lee, I-Chen Lin, Ai-Li Shiau, Pin Ling, Chao-Liang Wu
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1530 (2023)
The imbalance of mucosal immunity in the lower gastrointestinal tract can lead to chronic inflammatory bowel diseases (IBDs), including Crohn’s disease and ulcerative colitis. IBD is a chronic inflammatory disorder that causes small and/or large in
Externí odkaz:
https://doaj.org/article/272d0b8add514772b585d2d379284eb0