Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Ai Watanabe"'
Autor:
Ichiro Takasaki, Koji Nakamura, Ayaka Shimodaira, Ai Watanabe, Huy Du Nguyen, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Takashi Kurihara
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 2, Pp 129-132 (2019)
We recently developed PA-8, a novel small-molecule antagonist of PACAP type 1 (PAC1) receptor. In the present study, we examined whether PA-8 was effective against formalin-induced inflammatory pain in mice. Both intrathecal and oral administration o
Externí odkaz:
https://doaj.org/article/de65ba5ec5154b9380b8eb4928686c7f
Autor:
Munehiro Kitada, Yoshio Ogura, Taeko Suzuki, Itaru Monno, Keizo Kanasaki, Ai Watanabe, Daisuke Koya
Publikováno v:
Nutrition & Metabolism, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background The objective of this study is to investigate the effects of a low-protein diet (LPD) starting from a young age on diabetic status and renal injury in a rat model of type 2 diabetes and obesity. Methods Diabetic male Wistar fatty
Externí odkaz:
https://doaj.org/article/69d16806d672448ab76e17876a7cb233
Publikováno v:
Redox Report, Vol 23, Iss 1, Pp 153-159 (2018)
Objectives: Mitochondrial oxidative stress is involved in the pathogenesis of diabetic kidney disease. The objective of our study is to identify the mechanisms of renal mitochondrial oxidative stress, focusing on Sirt3, which is nicotinamide adenine
Externí odkaz:
https://doaj.org/article/e62bf0e3303a4c19a4468a90003a7708
Autor:
Ai Watanabe, Norihisa Miki
Publikováno v:
Micromachines, Vol 10, Iss 7, p 429 (2019)
This paper proposes a connecting mechanism for artificial vessels, which can be attached/detached with ease and does not deteriorate the biocompatibility of the vessels at the joint. The inner surface of the artificial vessels is designed to have hig
Externí odkaz:
https://doaj.org/article/75d55c4273cc452393b452a92547cf7a
Autor:
Takeshi Igawa, Ai Watanabe, Atsushi Suzuki, Akihiko Kashiwagi, Keiko Kashiwagi, Anna Noble, Matt Guille, David E Simpson, Marko E Horb, Tamotsu Fujii, Masayuki Sumida
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133963 (2015)
The Western clawed frog, Xenopus tropicalis, is a highly promising model amphibian, especially in developmental and physiological research, and as a tool for understanding disease. It was originally found in the West African rainforest belt, and was
Externí odkaz:
https://doaj.org/article/4b0ce78a35d7463cab875aab594fc0ea
Autor:
Ai Watanabe, Taku Ito, Yoshiyuki Kawashima, Keiji Honda, Taro Fujikawa, Tomosuke Kitagawa, Takeshi Tsutsumi
Publikováno v:
Nippon Jibiinkoka Tokeibugeka Gakkai Kaiho(Tokyo). 125:1586-1592
Publikováno v:
Practica Oto-Rhino-Laryngologica. 115:999-1003
Publikováno v:
Life Science Alliance; Sep2022, Vol. 5 Issue 9, p1-16, 16p
Autor:
Ichiro Takasaki, Ai Watanabe, Takuya Okada, Daisuke Kanayama, Ryota Nagashima, Miyu Shudo, Ayaka Shimodaira, Kazuto Nunomura, Bangzhong Lin, Yurie Watanabe, Hiroaki Gouda, Atsuro Miyata, Takashi Kurihara, Naoki Toyooka
Publikováno v:
European Journal of Medicinal Chemistry. 231:114160
Since PA-8 (5-(4-(Allyloxy)-3-methoxyphenyl)-2-amino-5,8-dihydro-3H,6H-pyrido[2,3-d]pyrimidine-4,7-dione) was recently identified as a novel small-molecule antagonist of the pituitary adenylate cyclase-activating polypeptide (PACAP) type I (PAC1) rec
Autor:
Munehiro Kitada, Keizo Kanasaki, Ai Watanabe, Atsushi Nakagawa, Emi Kawakita, Nobuhiko Miyatake, Shin-ichi Tsuda, Yuiko Mizunuma, Hiroshi Minato, Fujimoto Shino, Kyoko Nitta, Keiji Shimada, Yuta Takagaki, Taro Hirai, Mizue Fujii, Susumu Takagi, Itaru Monno, Daisuke Koya, Takako Nagai, Yoshio Ogura
Publikováno v:
Clinical Case Reports
Key Clinical Message Vitamin D plays vital role for the health, and its deficiency has been implicated in the diverse pathological conditions such as hypomagnesemia and abnormal immune system. Here, we present a case of severe electrolytes disorders