Výsledky vyhledávání

Akademický článek

Development of multiple AI pipelines that predict neoadjuvant chemotherapy response of breast cancer using H&E‐stained tissues

Autor: Bin Shen, Akira Saito, Ai Ueda, Koji Fujita, Yui Nagamatsu, Mikihiro Hashimoto, Masaharu Kobayashi, Aashiq H Mirza, Hans Peter Graf, Eric Cosatto, Shoichi Hazama, Hiroaki Nagano, Eiichi Sato, Jun Matsubayashi, Toshitaka Nagao, Esther Cheng, Syed AF Hoda, Takashi Ishikawa, Masahiko Kuroda

Publikováno v: The Journal of Pathology: Clinical Research, Vol 9, Iss 3, Pp 182-194 (2023)

Abstract In recent years, the treatment of breast cancer has advanced dramatically and neoadjuvant chemotherapy (NAC) has become a common treatment method, especially for locally advanced breast cancer. However, other than the subtype of breast cance

Externí odkaz: https://doaj.org/article/31f0ebf38d2a45079aab44a7939e1ebb

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Akademický článek

Successful treatment of G-CSF-related aortitis with prednisolone during preoperative chemotherapy for breast cancer: a case report

Autor: Yoichi Koyama, Kayo Adachi, Mio Yagi, Yoko Go, Kyoko Orimoto, Saori Kawai, Natsuki Uenaka, Miki Okazaki, Mariko Asaoka, Saeko Teraoka, Ai Ueda, Kana Miyahara, Takahiko Kawate, Hiroshi Kaise, Kimito Yamada, Takashi Ishikawa

Publikováno v: Surgical Case Reports, Vol 7, Iss 1, Pp 1-5 (2021)

Abstract Background With the introduction of dose-dense therapy, the use of primary pegfilgrastim (PEG-G) has been increasing in breast cancer treatment. A rare side effect of PEG-G is aortitis. We describe a case of PEG-G-induced aortitis. Case pres

Externí odkaz: https://doaj.org/article/0c8c84f71cb54c438690a26f5a5b4e0c

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Akademický článek

Hereditary breast cancer associated with Cowden syndrome-related PTEN mutation with Lhermitte-Duclos disease

Autor: Fuyo Kimura, Ai Ueda, Eiichi Sato, Jiro Akimoto, Hiroshi Kaise, Kimito Yamada, Mari Hosonaga, Yuko Kawai, Saeko Teraoka, Miki Okazaki, Takashi Ishikawa

Publikováno v: Surgical Case Reports, Vol 3, Iss 1, Pp 1-6 (2017)

Abstract Background Cowden syndrome is characterized by multiple hamartomas in various tissues, including the skin, brain, breast, thyroid, mucous membrane, and gastrointestinal tract, and is reported to increase the risk of malignant disease. Case p

Externí odkaz: https://doaj.org/article/f7334edb4069468eb4ff8fd271cb6691

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Akademický článek

In Vitro Studies to Define the Cell-Surface and Intracellular Targets of Polyarginine-Conjugated Sodium Borocaptate as a Potential Delivery Agent for Boron Neutron Capture Therapy

Autor: Atsushi Fujimura, Seiji Yasui, Kazuyo Igawa, Ai Ueda, Kaori Watanabe, Tadashi Hanafusa, Yasuaki Ichikawa, Sachiko Yoshihashi, Kazuki Tsuchida, Atsunori Kamiya, Shuichi Furuya

Publikováno v: Cells, Vol 9, Iss 10, p 2149 (2020)

Boron neutron capture therapy (BNCT) requires pharmaceutical innovations and molecular-based evidence of effectiveness to become a standard cancer therapeutic in the future. Recently, in Japan, 4-borono-L-phenylalanine (BPA) was approved as a boron a

Externí odkaz: https://doaj.org/article/b4b42b5ee5c943a486f689fb325c03e4

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Beneficial effects of transdermal administration of tamoxifen on capsular contracture after breast implantation in murine models

Autor: Miki Okazaki, Masako Muguruma, Takako Komiya, Kana Miyahara, Takahiko Kawate, Ai Ueda, Saeko Teraoka, Mariko Asaoka, Eiichi Sato, Hajime Matsumura, Takashi Ishikawa

Publikováno v: Breast Cancer. 29:343-351

Capsular contracture is the most common complication with smooth-type silicone implants. We investigated the preventive effect of an active metabolite of tamoxifen, 4-hydroxytamoxifen (4-OH TAM), on capsular contracture.A silicone sheet was implanted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd952210a3c34ad21adecf2548b3f37
https://doi.org/10.1007/s12282-021-01316-y

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Successful treatment of G-CSF-related aortitis with prednisolone during preoperative chemotherapy for breast cancer: a case report

Autor: Takahiko Kawate, Yoichi Koyama, Mio Yagi, Kana Miyahara, Yoko Go, Saori Kawai, Saeko Teraoka, Hiroshi Kaise, Mariko Asaoka, Kayo Adachi, Miki Okazaki, Ai Ueda, Kyoko Orimoto, Natsuki Uenaka, Takashi Ishikawa, Kimito Yamada

Publikováno v: Surgical Case Reports, Vol 7, Iss 1, Pp 1-5 (2021)
Surgical Case Reports

Background With the introduction of dose-dense therapy, the use of primary pegfilgrastim (PEG-G) has been increasing in breast cancer treatment. A rare side effect of PEG-G is aortitis. We describe a case of PEG-G-induced aortitis. Case presentation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a849bc3a132d3aec4bfa8bd9fbf83626
https://doaj.org/article/0c8c84f71cb54c438690a26f5a5b4e0c

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Differences in drug sensitivity between two-dimensional and three-dimensional culture systems in triple-negative breast cancer cell lines

Autor: Masako Muguruma, Masahiko Kuroda, Kana Miyahara, Miki Okazaki, Saeko Teraoka, Mariko Asaoka, Ai Ueda, Takahiko Kawate, Takashi Ishikawa, Yohei Miyagi

Publikováno v: Biochemical and Biophysical Research Communications. 533:268-274

Three-dimensional (3D) culture reflects tumor biology complexities compared with two-dimensional (2D) culture. Thus, 3D culture has attracted attention in cell biology studies including drug sensitivity tests. Herein, we investigated differences in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc03c973bb03686e6b8440d804a583d
https://doi.org/10.1016/j.bbrc.2020.08.075

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