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Albumin domain mutants with enhanced Aβ binding capacity identified by phage display analysis for application in various peripheral Aβ elimination approaches of Alzheimer's disease treatment

Autor: Tatsuhiro Ishida, Victor Tuan Giam Chuang, Masaki Otagiri, Hiroshi Morioka, Keiichiro Okuhira, Yoshiaki Suwa, Yu Ishima, Toru Maruyama, Tetsuya Fukuda, Hiroshi Watanabe, Kohshi Kusumoto, Ai Mimono

Publikováno v: IUBMB lifeREFERENCES. 72(4)

Deposition of amyloid protein, particularly Aβ1-42 , is a major contributor to the onset of Alzheimer's disease (AD). However, almost no deposition of Aβ in the peripheral tissues could be found. Human serum albumin (HSA), the most abundant protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6100d9aa560df420ca5425aa052bce
https://pubmed.ncbi.nlm.nih.gov/31794135

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