Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ai Ling Tian"'
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTIn a recent paper in Science, Fidelle et al. unravel a gut immune checkpoint that is subverted by antibiotic treatment. Post-antibiotic dysbiosis of the ileum causes an increase in bile acids that downregulate MAdCAM−1, thereby triggering t
Externí odkaz:
https://doaj.org/article/42ad6abdc05048daa707a456a60607bf
Autor:
Xin Yu, Ai-Ling Tian, Ping Wang, Juanjuan Li, Juan Wu, Bei Li, Zhou Liu, Siqing Liu, Zhijie Gao, Si Sun, Shengrong Sun, Yi Tu, Qi Wu
Publikováno v:
Cell Stress, Vol 7, Iss 4, Pp 20-33 (2023)
Macrolide antibiotics are widely used antibacterial agents that are associated with autophagy inhibition. This study aimed to investigate the association between macrolide antibi-otics and malignant tumors, as well as the effect on autophagy, reactiv
Externí odkaz:
https://doaj.org/article/9fa465f30f3148a785c8cd5ca98ecab8
Autor:
Hui Chen, Shuai Zhang, Peng Liu, Yumei Li, Wei Xie, Yang Jin, Laurence Zitvogel, Hui Pan, Guido Kroemer, Oliver Kepp, Ai-Ling Tian, Liwei Zhao, Sijing Li, Misha Mao, Mengfei Guo, Jonathan G Pol
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 7 (2023)
Background Most immunotherapies approved for clinical use rely on the use of recombinant proteins and cell-based approaches, rendering their manufacturing expensive and logistics onerous. The identification of novel small molecule immunotherapeutic a
Externí odkaz:
https://doaj.org/article/0ce4324e6b9548779bfb8e3ff249065e
Autor:
Jiayin Deng, Ai-Ling Tian, Hui Pan, Allan Sauvat, Marion Leduc, Peng Liu, Liwei Zhao, Shuai Zhang, Hui Chen, Valérie Taly, Pierre Laurent-Puig, Laura Senovilla, Yingqiu Li, Guido Kroemer, Oliver Kepp
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Abstract Colorectal cancers (CRC) can be classified into four consensus molecular subtypes (CMS), among which CMS1 has the best prognosis, contrasting with CMS4 that has the worst outcome. CMS4 CRC is notoriously resistant against therapeutic interve
Externí odkaz:
https://doaj.org/article/db661fab98d84368a6c5b4303d5f4dd5
Autor:
Ai-Ling Tian, Qi Wu, Peng Liu, Liwei Zhao, Isabelle Martins, Oliver Kepp, Marion Leduc, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract The integrated stress response manifests with the phosphorylation of eukaryotic initiation factor 2α (eIF2α) on serine residue 51 and plays a major role in the adaptation of cells to endoplasmic reticulum stress in the initiation of autoph
Externí odkaz:
https://doaj.org/article/1a35e7ecd947425a8fb6686b454dcf3a
Autor:
Mingmin Lu, Xiaowei Tian, Yang Zhang, Wenjuan Wang, Ai-Ling Tian, Kalibixiati Aimulajiang, Lianrui Liu, Charles Li, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li
Publikováno v:
Veterinary Research, Vol 52, Iss 1, Pp 1-16 (2021)
Abstract Unlike the successful immunization of native H. contortus antigens that contributed to the realization of the first commercial vaccine Barbervax, not many studies revealed the encouraging protective efficacies of recombinant H. contortus ant
Externí odkaz:
https://doaj.org/article/08f947352cc04004a7a4a89a3881a5f0
Autor:
Mingmin Lu, Xiaowei Tian, Zhang Yang, Wenjuan Wang, Ai-Ling Tian, Charles Li, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li
Publikováno v:
Veterinary Research, Vol 51, Iss 1, Pp 1-14 (2020)
Abstract Haemonchus contortus has evolved highly integrated and sophisticated mechanisms to promote coexistence with hosts. The excretory-secretory (ES) products generated by this parasite contribute to the regulation of the host immune response to f
Externí odkaz:
https://doaj.org/article/2daef7a1c7b24f41a1a9b9ee74aebc0a
Autor:
Qi Wu, Shuai Zhang, Peng Liu, Wei Xie, Guido Kroemer, Oliver Kepp, Bei Li, Pan Hui, Ai-Ling Tian, Marion Leduc, Sabrina Forveille, Peter Hamley, Warren Galloway, Liwei Zhao, Frank Madeo, Yi Tu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Pharmacological autophagy enhancement constitutes a preclinically validated strategy for preventing or treating most major age-associated diseases. Driven by this consideration, we performed a high-content/high-throughput screen on 65 000
Externí odkaz:
https://doaj.org/article/4059f46f37954dd193fb55bc97c710ab
Autor:
Sha-Sha Wang, Dan Chen, Jun-Jun He, Wen-Bin Zheng, Ai-Ling Tian, Guang-Hui Zhao, Hany M. Elsheikha, Xing-Quan Zhu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Fasciola gigantica produces excretory-secretory products (ESPs) with immune-modulating effects to promote its own survival. In this study, we performed RNA-seq to gain a comprehensive global understanding of changes in the expression of mRNAs, miRNAs
Externí odkaz:
https://doaj.org/article/41c5cdbf294f47b59401659d1bf89751
Autor:
Mingmin Lu, Xiaowei Tian, Ai-Ling Tian, Charles Li, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The α/β-hydrolase domain (ABHD) proteins belonging to α/β-hydrolase (ABH) superfamily are ubiquitously distributed throughout all the organisms, and their functional roles have been implicated in energy metabolism, cell signaling, growth and deve
Externí odkaz:
https://doaj.org/article/56caf2fcc97a406e8b04bc922eb04698