Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ai Leng Liang"'
Autor:
Jeanette Marjorie Wood, Kantharaj Ethirajulu, Haishan Wang, Stefan Hart, Hannes Hentze, Kee Chuan Goh, Zahid Bonday, Yung Kiang Loh, Ai Leng Liang, Sven Pettersson, Gediminas Greicius, Pauline Yeo, Nina Sausgruber, Xiaofeng Wu, Chang Yong Hu, Kanda Sangthongpitag, Veronica Novotny-Diermayr
Supplementary Figures and Materials and Metholds from SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b51e86e9b7513857bdd252443925fa
https://doi.org/10.1158/1535-7163.22485351.v1
https://doi.org/10.1158/1535-7163.22485351.v1
Autor:
Jeanette Marjorie Wood, Kantharaj Ethirajulu, Haishan Wang, Stefan Hart, Hannes Hentze, Kee Chuan Goh, Zahid Bonday, Yung Kiang Loh, Ai Leng Liang, Sven Pettersson, Gediminas Greicius, Pauline Yeo, Nina Sausgruber, Xiaofeng Wu, Chang Yong Hu, Kanda Sangthongpitag, Veronica Novotny-Diermayr
Supplementary Table 2 from SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45515ad58f3fa654f42c307ee91c362b
https://doi.org/10.1158/1535-7163.22485345
https://doi.org/10.1158/1535-7163.22485345
Autor:
Jeanette Marjorie Wood, Kantharaj Ethirajulu, Haishan Wang, Stefan Hart, Hannes Hentze, Kee Chuan Goh, Zahid Bonday, Yung Kiang Loh, Ai Leng Liang, Sven Pettersson, Gediminas Greicius, Pauline Yeo, Nina Sausgruber, Xiaofeng Wu, Chang Yong Hu, Kanda Sangthongpitag, Veronica Novotny-Diermayr
Supplementary Table 1 from SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea26232b2120ba418d9671855d8e245c
https://doi.org/10.1158/1535-7163.22485348.v1
https://doi.org/10.1158/1535-7163.22485348.v1
Autor:
Jeanette Marjorie Wood, Kantharaj Ethirajulu, Haishan Wang, Stefan Hart, Hannes Hentze, Kee Chuan Goh, Zahid Bonday, Yung Kiang Loh, Ai Leng Liang, Sven Pettersson, Gediminas Greicius, Pauline Yeo, Nina Sausgruber, Xiaofeng Wu, Chang Yong Hu, Kanda Sangthongpitag, Veronica Novotny-Diermayr
Supplementary Table 3 from SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab078191ad592debcca47d0ad3279d38
https://doi.org/10.1158/1535-7163.22485342.v1
https://doi.org/10.1158/1535-7163.22485342.v1
Autor:
Jeanette Marjorie Wood, Kantharaj Ethirajulu, Haishan Wang, Stefan Hart, Hannes Hentze, Kee Chuan Goh, Zahid Bonday, Yung Kiang Loh, Ai Leng Liang, Sven Pettersson, Gediminas Greicius, Pauline Yeo, Nina Sausgruber, Xiaofeng Wu, Chang Yong Hu, Kanda Sangthongpitag, Veronica Novotny-Diermayr
Although clinical responses in liquid tumors and certain lymphomas have been reported, the clinical efficacy of histone deacetylase inhibitors in solid tumors has been limited. This may be in part due to the poor pharmacokinetic of these drugs, resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bfd470f6ae571ff56fa8b9560145061
https://doi.org/10.1158/1535-7163.c.6531900
https://doi.org/10.1158/1535-7163.c.6531900
Autor:
Smita Sampath, Michael Klimas, Dai Feng, Richard Baumgartner, Elaine Manigbas, Ai-Leng Liang, Jeffrey L Evelhoch, Chih-Liang Chin
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127947 (2015)
Pre-clinical animal models are important to study the fundamental biological and functional mechanisms involved in the longitudinal evolution of heart failure (HF). Particularly, large animal models, like nonhuman primates (NHPs), that possess greate
Externí odkaz:
https://doaj.org/article/41f75f469a8343608bc600d11085d582
Autor:
Tony Kiat Hon Lim, Daniela I. Drautz–Moses, Sven Pettersson, Stephan C. Schuster, Edwin Yang, Oliver Worsley, Vanessa Fan, Wilson Lek Wen Tan, Septian Hartono, Hyejin Kim, Rikky W. Purbojati, Roger Foo, Ai Leng Liang, Pierce K. H. Chow
Publikováno v:
Cellular and molecular life sciences : CMLS. 76(21)
Non-alcoholic fatty liver disease (NAFLD) is a metabolic liver disease that is thought to be reversible by changing the diet. To examine the impact of dietary changes on progression and cure of NAFLD, we fed mice a high-fat diet (HFD) or high-fructos
Autor:
Haishan Wang, Jeanette Marjorie Wood, V Novotny-Diermayr, Nina Sausgruber, Stefan Hart, Sven Pettersson, Ai Leng Liang, Gediminas Greicius, Kee Chuan Goh, Kanda Sangthongpitag, Pauline Yeo, Xiaofeng Wu, Kantharaj Ethirajulu, Chang Yong Hu, Yung Kiang Loh, Zahid Bonday, Hannes Hentze
Publikováno v:
Molecular Cancer Therapeutics. 9:642-652
Although clinical responses in liquid tumors and certain lymphomas have been reported, the clinical efficacy of histone deacetylase inhibitors in solid tumors has been limited. This may be in part due to the poor pharmacokinetic of these drugs, resul
Autor:
Chih-Liang Chin, Richard Baumgartner, Michael Klimas, Dai Feng, Jeffrey L. Evelhoch, Smita Sampath, Ai-Leng Liang, Elaine Manigbas
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127947 (2015)
PLoS ONE
PLoS ONE
Pre-clinical animal models are important to study the fundamental biological and functional mechanisms involved in the longitudinal evolution of heart failure (HF). Particularly, large animal models, like nonhuman primates (NHPs), that possess greate
Autor:
Jeanette Marjorie Wood, Sara Zaknoen, Miah Kiat Goh, Stefan Hart, Chung Ong, Anthony D. William, Kantharaj Ethirajalu, Yung Kiang Loh, Hannes Hentze, Kee Chuan Goh, Yong-Cheng Tan, Francis Burrows, Veronica Novotny-Diermayr, Brian W. Dymock, Ai Leng Liang
Publikováno v:
Cancer Research. 70:2542-2542
Kinase inhibitors have found applications in multiple oncology settings due to their ability to target key signaling pathways in many different cancers. In general, the broad-spectrum kinase inhibitors have yielded better clinical outcomes than more