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pro vyhledávání: '"Ai H. Mai"'
Publikováno v:
Journal of the American Chemical Society. 135:9149-9155
Complexes formed between phi29 DNA polymerase (DNAP) and DNA fluctuate discretely between the pre-translocation and post-translocation states on the millisecond time scale. The translocation fluctuations can be observed in ionic current traces when i
Publikováno v:
Journal of the American Chemical Society. 134:18816-18823
Complexes formed between the bacteriophage phi29 DNA polymerase (DNAP) and DNA fluctuate between the pre-translocation and post-translocation states on the millisecond time scale. These fluctuations can be directly observed with single-nucleotide pre
Autor:
Andre Marziali, Ai H. Mai, Hongyun Wang, Mark Akeson, Nahid N. Jetha, Joseph M. Dahl, Gerald M. Cherf, Kate R. Lieberman, Daniel R. Garalde
Publikováno v:
Journal of Biological Chemistry. 287:13407-13421
Complexes of phi29 DNA polymerase and DNA fluctuate on the millisecond time scale between two ionic current amplitude states when captured atop the α-hemolysin nanopore in an applied field. The lower amplitude state is stabilized by complementary dN