Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Ai‑Wu Ke"'
Autor:
Dao-Han Zhang, Chen Liang, Shu-Yang Hu, Xiao-Yong Huang, Lei Yu, Xian-Long Meng, Xiao-Jun Guo, Hai-Ying Zeng, Zhen Chen, Lv Zhang, Yan-Zi Pei, Mu Ye, Jia-Bin Cai, Pei-Xin Huang, Ying-Hong Shi, Ai-Wu Ke, Yi Chen, Yuan Ji, Yujiang Geno Shi, Jian Zhou, Jia Fan, Guo-Huan Yang, Qi-Man Sun, Guo-Ming Shi, Jia-Cheng Lu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Single-cell technology depicts integrated tumor profiles including both tumor cells and tumor microenvironments, which theoretically enables more robust diagnosis than traditional diagnostic standards based on only pathology. However, the in
Externí odkaz:
https://doaj.org/article/e9d2b0231e9149bfa667fd275a856f8c
Autor:
Xiao-Yong Huang, Peng-Fei Zhang, Chuan-Yuan Wei, Rui Peng, Jia-Cheng Lu, Chao Gao, Jia-Bing Cai, Xuan Yang, Jia Fan, Ai-Wu Ke, Jian Zhou, Guo-Ming Shi
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/bdcd72e2e2ba4c77a0959de715d9e2b2
Autor:
Jia-Cheng Lu, Lei-Lei Wu, Yi-Ning Sun, Xiao-Yong Huang, Chao Gao, Xiao-Jun Guo, Hai-Ying Zeng, Xu-Dong Qu, Yi Chen, Dong Wu, Yan-Zi Pei, Xian-Long Meng, Yi-Min Zheng, Chen Liang, Peng-Fei Zhang, Jia-Bin Cai, Zhen-Bin Ding, Guo-Huan Yang, Ning Ren, Cheng Huang, Xiao-Ying Wang, Qiang Gao, Qi-Man Sun, Ying-Hong Shi, Shuang-Jian Qiu, Ai-Wu Ke, Guo-Ming Shi, Jian Zhou, Yi-Di Sun, Jia Fan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Intratumoral immune status influences tumor therapeutic response, but it remains largely unclear how the status determines therapies for patients with intrahepatic cholangiocarcinoma. Here, we examine the single-cell transcriptional and TCR
Externí odkaz:
https://doaj.org/article/1395aad7bace40e0b84d6d1fe593d121
Autor:
Xiao-Jun Guo, Xiao-Yong Huang, Xuan Yang, Jia-Cheng Lu, Chuan-Yuan Wei, Chao Gao, Yan-Zi Pei, Yi Chen, Qi-Man Sun, Jia-Bin Cai, Jian Zhou, Jia Fan, Ai-Wu Ke, Yujiang G. Shi, Ying-Hao Shen, Peng-Fei Zhang, Guo-Ming Shi, Guo-Huan Yang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-13 (2023)
Abstract Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epi
Externí odkaz:
https://doaj.org/article/8f8e73cbe0eb4e2faf63bf7b0d991349
Autor:
Zheng Gao, Shan-Ru Feng, Jia‑Feng Chen, Xiao‑Gang Li, Ying‑Hong Shi, Zheng Tang, Wei‑Ren Liu, Xin Zhang, Ao Huang, Xuan‑Ming Luo, Hai-Ying Zeng, Qiang Gao, Guo‑Ming Shi, Ai‑Wu Ke, Jian Zhou, Jia Fan, Xiu‑Tao Fu, Zhen‑Bin Ding
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114560- (2023)
Hepatocellular carcinoma (HCC) has a complex and changeable tumor microenvironment. Despite emerging evidence focusing on autophagy process within immune cells, the function and regulatory mechanism of macrophage autophagy in tumor progression remain
Externí odkaz:
https://doaj.org/article/24682435c4214c099f1a7c596e7ff5a5
Autor:
Chao Gao, Si-wei Wang, Jia-cheng Lu, Xiao-qiang Chai, Yuan-cheng Li, Peng-fei Zhang, Xiao-yong Huang, Jia-bin Cai, Yi-min Zheng, Xiao-jun Guo, Guo-ming Shi, Ai-wu Ke, Jia Fan
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-19 (2022)
Abstract Background Kinase suppressor of Ras 2 (KSR2) is a regulator of MAPK signaling that is overactivated in most hepatocellular carcinoma (HCC). We sought to determine the role of KSR2 in HCC pathogenesis. Methods We tested the level of KSR2 in H
Externí odkaz:
https://doaj.org/article/1420ed705a324cb1a2f47b22f124007a
Autor:
Zheng Gao, Jia-Feng Chen, Xiao-Gang Li, Ying-Hong Shi, Zheng Tang, Wei-Ren Liu, Xin Zhang, Ao Huang, Xuan-Ming Luo, Qiang Gao, Guo-Ming Shi, Ai-Wu Ke, Jian Zhou, Jia Fan, Xiu-Tao Fu, Zhen-Bin Ding
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background While the correlation between PD-L1 expression and KRAS mutation has been previously reported in other solid tumors such as non-small cell lung cancer (NSCLC), whether PD-L1 can be modulated by ERK signaling downstream of KRAS in
Externí odkaz:
https://doaj.org/article/333fa9d23fd04e279c13aed5e784ca44
Autor:
Si-Wei Wang, Chao Gao, Yi-Min Zheng, Li Yi, Jia-Cheng Lu, Xiao-Yong Huang, Jia-Bin Cai, Peng-Fei Zhang, Yue-Hong Cui, Ai-Wu Ke
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-27 (2022)
Abstract Clustered regularly interspaced short palindromic repeats (CRISPR) system provides adaptive immunity against plasmids and phages in prokaryotes. This system inspires the development of a powerful genome engineering tool, the CRISPR/CRISPR-as
Externí odkaz:
https://doaj.org/article/5a7835501d414ee4871ede51627e5bac
Autor:
Jia-Cheng Lu, Peng-Fei Zhang, Xiao-Yong Huang, Xiao-Jun Guo, Chao Gao, Hai-Ying Zeng, Yi-Min Zheng, Si-Wei Wang, Jia-Bin Cai, Qi-Man Sun, Ying-Hong Shi, Jian Zhou, Ai-Wu Ke, Guo-Ming Shi, Jia Fan
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Background Immune checkpoint blockade resistance narrows the efficacy of cancer immunotherapies, but the underlying mechanism remains elusive. Delineating the inherent mechanisms of anti-PD1 resistance is important to improve outcome of pati
Externí odkaz:
https://doaj.org/article/3a9346748130408cbfa3d2dff395848d
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-16 (2021)
Abstract Background Cirrhosis is a recognized risk factor for developing hepatocellular carcinoma (HCC). Few studies have reported the expression profile of circRNAs in HCC samples compared to paratumour dysplastic nodule (DN) samples. Methods The Ar
Externí odkaz:
https://doaj.org/article/4b39c12480964ce48b208b39f766cc60