[THE EFFICACY AND SAFETY OF DEXMEDETOMIDINE FOR SEDATION OF PATIENTS DURING PROLONGED MECHANICAL VENTILATION IN INTENSIVE CARE UNITS (RUSSIAN MULTICENTER STUDY RESULTS)]

Autor: Vv, Nikoda, Ai, Gritsan, Aa, Eremenko, Igor Zabolotskikh, My, Kirov, Km, Lebedinsky, Al, Levit

Publikováno v: Europe PubMed Central

A multicenter prospective study investigated the efficacy and safety dexmedetomidine of sedation in 103 patients during long-term (12 h) mechanical ventilation and in cases of delirium. Protocol of sedation included intravenous infusions of dexmedeto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6f80b532e5aa25ec16b5959afd18e996
http://europepmc.org/abstract/med/26852580

Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis.

Autor: Maddali MV; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Stanford University, Stanford, CA, USA; Division of Hospital Medicine, University of California, San Francisco, San Francisco, CA, USA., Churpek M; Division of Allergy, Pulmonary, and Critical Care, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Pham T; Service de Médecine Intensive-Réanimation, AP-HP, Hôpital de Bicêtre, DMU 4 CORREVE Maladies du Cœur et des Vaisseaux, FHU Sepsis, Groupe de Recherche Clinique CARMAS, Le Kremlin-Bicêtre, France; Université Paris-Saclay, UVSQ, Université Paris-Sud, Inserm U1018, Equipe d'Epidémiologie Respiratoire Intégrative, CESP, 94807, Villejuif, France., Rezoagli E; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy., Zhuo H; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Zhao W; Division of Hospital Medicine, University of California, San Francisco, San Francisco, CA, USA., He J; Division of Clinical and Translational Research, Washington University School of Medicine, St Louis, MO, USA., Delucchi KL; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA., Wang C; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Wickersham N; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., McNeil JB; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Jauregui A; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Ke S; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Vessel K; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Gomez A; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, CA, USA., Hendrickson CM; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, CA, USA., Kangelaris KN; Division of Hospital Medicine, University of California, San Francisco, San Francisco, CA, USA., Sarma A; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA., Leligdowicz A; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada., Liu KD; Division of Nephrology, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA., Matthay MA; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA; Department of Anesthesia, University of California, San Francisco, San Francisco, CA, USA., Ware LB; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Laffey JG; School of Medicine, Regenerative Medicine Institute at CÚRAM Centre for Research in Medical Devices, National University of Ireland Galway, Galway, Ireland; Anaesthesia and Intensive Care Medicine, Galway University Hospitals, Galway, Ireland., Bellani G; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; Department of Anesthesia and Intensive Care Medicine, ASST Monza-Ospedale San Gerardo, Monza, Italy., Calfee CS; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Anesthesia, University of California, San Francisco, San Francisco, CA, USA., Sinha P; Division of Clinical and Translational Research, Washington University School of Medicine, St Louis, MO, USA; Department of Anesthesia, Division of Critical Care, Washington University, St Louis, MO, USA. Electronic address: p.sinha@wustl.edu.

Publikováno v: The Lancet. Respiratory medicine [Lancet Respir Med] 2022 Apr; Vol. 10 (4), pp. 367-377. Date of Electronic Publication: 2022 Jan 10.

Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study.

Autor: Pham T; Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Unity Heath Toronto, Toronto, ON, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.; Université Paris-Saclay, AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, FHU SEPSIS, Groupe de recherche clinique CARMAS, Le Kremlin-Bicêtre, France.; Université Paris-Saclay, UVSQ, Université Paris-Sud, Inserm, Equipe d'Epidémiologie respiratoire intégrative, CESP, Villejuif, France., Pesenti A; Dipartimento di Anestesia, Rianimazione ed Emergenza Urgenza, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.; Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milan, Italy., Bellani G; School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.; Dept of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy., Rubenfeld G; Interdepartmental Division of Critical Care Medicine, University of Toronto and Program in Trauma, Emergency and Critical Care, Sunnybrook Health Sciences Center, Toronto, ON, Canada., Fan E; Dept of Medicine, University Health Network and Mount Sinai Hospital, Toronto, ON, Canada.; Interdepartmental Division of Critical Care Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada., Bugedo G; Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile., Lorente JA; Critical Care Dept, Hospital Universitario de Getafe, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Universidad Europea, Madrid, Spain., Fernandes ADV; Serviço de Medicina Intensiva, Hospital Garcia de Orta, E.P.E, Almada, Portugal., Van Haren F; Intensive Care Unit, Canberra Hospital, Garran, Australia.; Australian National University Medical School, Canberra Hospital, Garran, Australia.; University of Canberra, Faculty of Health, Canberra, Australia., Bruhn A; Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile., Rios F; Intensive Care Unit, Hospital Nacional Alejandro Posadas, Buenos Aires, Argentina., Esteban A; Hospital Universitario de Getafe, Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Gattinoni L; University of Göttingen, Dept of Anaesthesiology, Emergency and Intensive Care Medicine, Göttingen, Germany., Larsson A; Dept of Medical Sciences, Uppsala University, Uppsala, Sweden., McAuley DF; Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.; Regional Intensive Care Unit, Royal Victoria Hospital, Belfast, UK., Ranieri M; Alma Mater Studiorum-Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche, Anesthesia and Intensive Care Medicine, Policlinico di Sant'Orsola, Bologna, Italy., Thompson BT; Massachusetts General Hospital, Harvard School of Medicine, Division of Pulmonary and Critical Care Medicine, Dept of Medicine, Boston, MA, USA., Wrigge H; Dept of Anesthesiology and Intensive Care Medicine, University Hospital Leipzig, Leipzig, Germany.; Dept of Anesthesiology, Intensive Care and Emergency Medicine, Pain Therapy, Bergmannstrost Hospital Halle, Halle, Germany., Brochard LJ; Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Unity Heath Toronto, Toronto, ON, Canada Laurent.brochard@unityhealth.to.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.; Co-senior authors., Laffey JG; Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Unity Heath Toronto, Toronto, ON, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.; Dept of Anesthesia, St Michael's Hospital and University of Toronto, Toronto, ON, Canada.; School of Medicine, and Regenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, National University of Ireland Galway, Galway, Ireland.; Co-senior authors.

Publikováno v: The European respiratory journal [Eur Respir J] 2021 Jun 10; Vol. 57 (6). Date of Electronic Publication: 2021 Jun 10 (Print Publication: 2021).

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study.

Autor: Madotto F; Research Center on Public Health, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.; Scientific Institute for Research, Hospitalization and Health Care, IRCCS Multimedica, Sesto San Giovanni, Milan, Italy., Rezoagli E; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.; Anaesthesia and Intensive Care Medicine, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Regenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, Biomedical Sciences Building, National University of Ireland Galway, Galway, Ireland., Pham T; Keenan Research Centre for Biomedical Science, St Michael's Hospital, Toronto, Canada.; Department of Critical Care Medicine, St Michael's Hospital, Toronto, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada., Schmidt M; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada., McNicholas B; Nephrology, School of Medicine, National University of Ireland Galway, Galway, Ireland., Protti A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy.; Humanits clinical and research center - IRCCS, Rozzano (Milan), Italy., Panwar R; Intensive Care Unit, John Hunter Hospital, New Lambton Heights, NSW, Australia.; School of Medicine and Public Health, University of Newcastle, Newcastle, Australia., Bellani G; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.; Department of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy., Fan E; Anaesthesia and Intensive Care Medicine, School of Medicine, National University of Ireland Galway, Galway, Ireland.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.; Department of Medicine, University Health Network and Sinai Health System, Toronto, Canada., van Haren F; Intensive Care Unit, The Canberra Hospital and Australian National University, Canberra, Australia., Brochard L; Keenan Research Centre for Biomedical Science, St Michael's Hospital, Toronto, Canada.; Department of Critical Care Medicine, St Michael's Hospital, Toronto, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada., Laffey JG; Anaesthesia and Intensive Care Medicine, School of Medicine, National University of Ireland Galway, Galway, Ireland. john.laffey@nuigalway.ie.; Regenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, Biomedical Sciences Building, National University of Ireland Galway, Galway, Ireland. john.laffey@nuigalway.ie.; Keenan Research Centre for Biomedical Science, St Michael's Hospital, Toronto, Canada. john.laffey@nuigalway.ie.

Publikováno v: Critical care (London, England) [Crit Care] 2020 Mar 31; Vol. 24 (1), pp. 125. Date of Electronic Publication: 2020 Mar 31.

Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.

Autor: van Haren F, Pham T, Brochard L; Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada., Bellani G; School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.; Department of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy., Laffey J; Departments of Anesthesia and Critical Care Medicine, Keenan Research Centre for Biomedical Science, St Michael's Hospital, Toronto, ON, Canada.; Departments of Anesthesia, Physiology, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada., Dres M; Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, ON, Canada.; Respiratory and Critical Care Department, Pitié Salpetriere Hospital, APHP, Paris, France., Fan E; Department of Medicine, University Health Network, Mount Sinai Hospital, Toronto, ON, Canada.; Interdepartmental Division of Critical Care Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada., Goligher EC; Division of Respirology, Department of Medicine, University Health Network, Toronto, ON, Canada.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada., Heunks L; Department of Intensive Care Medicine, VU University Medical Centre Amsterdam, The Netherlands., Lynch J; ICU, Liverpool Hospital, Sydney, NSW, Australia.; Critical Care Research in Collaboration and Evidence Translation (CCRICET), Western Sydney University and Liverpool Hospital, Sydney, NSW, Australia., Wrigge H; Department of Anaesthesiology and Intensive Care Medicine, University of Leipzig, Leipzig, Germany.; Department of Anaesthesiology, Intensive Care and Emergency Medicine, Bergmannstrost Hospital, Halle, Germany., McAuley D; Centre for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast, Northern Ireland.; Regional Intensive Care Unit, Royal Victoria Hospital, 274 Grosvenor Road, Belfast, Northern Ireland.

Publikováno v: Critical care medicine [Crit Care Med] 2019 Feb; Vol. 47 (2), pp. 229-238.