Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ahsen Özcan"'
Autor:
Omar O. Abudayyeh, Jonathan S. Gootenberg, Rohan N. Krajeski, Eugene V. Koonin, Eleonora I. Ioannidi, Ahsen Özcan, Brennan Peter Lee, Kira S. Makarova, Apolonia Gardner
Publikováno v:
Nature. 597:720-725
CRISPR–Cas interference is mediated by Cas effector nucleases that are either components of multisubunit complexes—in class 1 CRISPR–Cas systems—or domains of a single protein—in class 2 systems1–3. Here we show that the subtype III-E eff
Autor:
Ahsen Özcan, Rohan Krajeski, Eleonora Ioannidi, Brennan Lee, Apolonia Gardner, Kira S. Makarova, Eugene V. Koonin, Omar O. Abudayyeh, Jonathan S. Gootenberg
Publikováno v:
Nature. 608:E30-E30
Autor:
Ayça Nur Demir, Mehmet Ozsoz, Abdullah Tozluyurt, Ali Kerem Kalkan, Ozgur Can, Fahreddin Palaz, Ahsen Özcan
Over the past decades, significant progress has been made in targeted cancer therapy. In precision oncology, molecular profiling of cancer patients enables the use of targeted cancer therapeutics. However, current diagnostic methods for molecular ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e4ff134a2e1e2750e8c24ff1cae93e
https://aperta.ulakbim.gov.tr/record/239840
https://aperta.ulakbim.gov.tr/record/239840
Autor:
Ahsen Özcan, Gert Bange, Andreas Linden, Henning Urlaub, Johann Heider, Lennart Randau, Patrick Pausch, Karola Schühle, Alexander Wulf, Thomas Heimerl
Publikováno v:
Nature Microbiology
Type IV CRISPR–Cas modules belong to class 1 prokaryotic adaptive immune systems, which are defined by the presence of multisubunit effector complexes. They usually lack the known Cas proteins involved in adaptation and target cleavage, and their f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5c8dd77b61c22fcc883b8c4da8d1a0
https://hdl.handle.net/21.11116/0000-0002-7120-A21.11116/0000-0002-A48A-921.11116/0000-0002-A48B-821.11116/0000-0002-A48C-721.11116/0000-0002-A48D-6
https://hdl.handle.net/21.11116/0000-0002-7120-A21.11116/0000-0002-A48A-921.11116/0000-0002-A48B-821.11116/0000-0002-A48C-721.11116/0000-0002-A48D-6
Autor:
Patrick Pausch, Xiaohan Guo, Daniel Gleditzsch, Gert Bange, Hanna Müller-Esparza, Ahsen Özcan, Lennart Randau
Publikováno v:
RNA Biology
Adaptive immunity of prokaryotes is mediated by CRISPR-Cas systems that employ a large variety of Cas protein effectors to identify and destroy foreign genetic material. The different targeting mechanisms of Cas proteins rely on the proper protection