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Akademický článek

Crystal structure of Kunitz-type trypsin inhibitor: Entomotoxic effect of native and encapsulated protein targeting gut trypsin of Tribolium castaneum Herbst

Autor: Sohaib Mehmood, Soren Skou Thirup, Sarah Ahmed, Nabila Bashir, Ahsan Saeed, Maria Rafiq, Qamar Saeed, Muhammad Najam-ul-Haq, Binish Khaliq, Muhammad Ibrahim, Wadi Brak Alonazi, Ahmed Akrem

Publikováno v: Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3132-3142 (2024)

Trypsin inhibitors are known to act against insect pests by inhibiting proteases of the digestive tract. In this study, we report structural and functional characterization of ∼ 19 kDa Albizia procera Kunitz-type trypsin inhibitor (ApKTI) protein w

Externí odkaz: https://doaj.org/article/ad22d719ebfd4d7d9e9793837ed64ca7

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Akademický článek

Studies Calculated a New Chitin Oligomer Binding Site Inside Vicilin: A Potent Antifungal and Insecticidal Agent

Autor: Ahsan Saeed, Zahra Rafiq, Muhammad Imran, Qamar Saeed, Muhammad Q. Saeed, Zahid Ali, Rana K. Iqbal, Saber Hussain, Binish Khaliq, Sohaib Mehmood, Ahmed Akrem

Publikováno v: Dose-Response, Vol 20 (2022)

Vicilins are major seed storage proteins and show differential binding affinities toward sugar moieties of fungal cell wall and insect gut epithelium. Hence, purpose of study is the thorough in-silico characterization of interactions between vicilin

Externí odkaz: https://doaj.org/article/2a0a5b09d83f4417bb44de9c3948ea3e

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Akademický článek

Exploring Pakistani Physicians' Knowledge and Practices Regarding High Alert Medications: Findings and Implications

Autor: Zia Ul Mustafa, Shahzaib Haroon, Naeem Aslam, Ahsan Saeed, Muhammad Salman, Khezar Hayat, Naureen Shehzadi, Khalid Hussain, Amer Hayat Khan

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Introduction: While many low-middle income countries (LMICs), including Pakistan, try and ensure patient safety within available resources, there are considerable concerns with medication use. Unsafe and inappropriate medication use, especially high

Externí odkaz: https://doaj.org/article/89fe87077e644728a58e7b9766cab1e5

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Akademický článek

In Silico Analysis and Functional Characterization of Antimicrobial and Insecticidal Vicilin from Moth Bean (Vigna aconitifolia (Jacq.) Marechal) Seeds

Autor: Muhammad Ateeq, Muhammad Muzammal Adeel, Ayesha Kanwal, Muhammad Tahir ul Qamar, Ahsan Saeed, Binish Khaliq, Qamar Saeed, Muhammad Nauman Atiq, Muhammad Bilal, Metab Alharbi, Abdulrahman Alshammari, Ahmed Akrem

Publikováno v: Molecules, Vol 27, Iss 10, p 3251 (2022)

Vicilin has nutraceutical potential and different noteworthy medicative health-promoting biotic diversions, and it is remarkable against pathogenic microorganisms and insects. In this study, Vigna aconitifolia vicilin (VacV) has been identified and c

Externí odkaz: https://doaj.org/article/d37cecb063ad420d96058fe80ba49b66

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