Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?

Autor: Du R; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Zhang J; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Lukas RV; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Tripathi S; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Ahrendsen JT; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA (J.T.A.).; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Curran MA; Department of Immunology, MD Anderson Cancer Center, the University of Texas, Houston, Texas, USA., Dmello C; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Zhang P; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Stupp R; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Rao G; Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA., Heimberger AB; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 Oct 19. Date of Electronic Publication: 2024 Oct 19.

Amniotic Fluid Embolism: An Illustrated Report and Review of Literature.

Autor: Kostelecky N; From the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL., Loxas M; From the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL., Multz R; From the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL., Flanagan ME, Ahrendsen JT; From the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL., Goldstein J; From the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Publikováno v: The American journal of forensic medicine and pathology [Am J Forensic Med Pathol] 2024 Dec 01; Vol. 45 (4), pp. e107-e109. Date of Electronic Publication: 2024 Jun 12.

Diagnostic utility of multimodal advanced molecular testing to classify metastases of unknown primaries: A case of a patient with no known medical history.

Autor: Smith H; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Jean J; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Duckett D; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Vormittag-Nocito E; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Nezami BG; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Jennings LJ; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Ahrendsen JT; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Yang XJ; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Primdahl D; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Conway K; Department of Pathology, University of Michigan, Ann Arbor, MI, United States., Zhong W; Great Lakes Pathologists, SC, Milwaukee, WI, United States., Santana-Santos L; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Horbinski C; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Castellani RJ; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Sukhanova M; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Jamshidi P; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.

Publikováno v: Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2024 Jul 31. Date of Electronic Publication: 2024 Jul 31.

Understanding the glioblastoma tumor microenvironment: leveraging the extracellular matrix to increase immunotherapy efficacy.

Autor: Collado J; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Boland L; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States., Ahrendsen JT; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Miska J; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Lurie Cancer Center, Lou and Jean Malnati Brain Tumor Institute, Chicago, IL, United States., Lee-Chang C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Lurie Cancer Center, Lou and Jean Malnati Brain Tumor Institute, Chicago, IL, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Feb 06; Vol. 15, pp. 1336476. Date of Electronic Publication: 2024 Feb 06 (Print Publication: 2024).

CD8 cytotoxic T-cell infiltrates and cellular damage in the hypothalamus in human obesity.

Autor: Ahrendsen JT; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Nong Y; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.; Neuroscience Therapeutic Focus Area, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Huo Y; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.; Neuroscience Therapeutic Focus Area, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Steele J; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Anderson MP; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA. matthewanderson020@gmail.com.; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA. matthewanderson020@gmail.com.; Neuroscience Therapeutic Focus Area, Regeneron Pharmaceuticals, Tarrytown, NY, USA. matthewanderson020@gmail.com.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Oct 09; Vol. 11 (1), pp. 163. Date of Electronic Publication: 2023 Oct 09.