Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ahola-Olli AV"'
Autor:
Davies, G, Lam, M, Harris, SE, Trampush, JW, Luciano, M, Hill, WD, Hagenaars, SP, Ritchie, SJ, Marioni, RE, Fawns-Ritchie, C, Liewald, DCM, Okely, JA, Ahola-Olli, AV, Barnes, CLK, Bertram, L, Bis, JC, Burdick, KE, Christoforou, A, Derosse, P, Djurovic, S, Espeseth, T, Giakoumaki, S, Giddaluru, S, Gustavson, DE, Hayward, C, Hofer, E, Ikram, MA, Karlsson, R, Knowles, E, Lahti, J, Leber, M, Li, S, Mather, KA, Melle, I, Morris, D, Oldmeadow, C, Palviainen, T, Payton, A, Pazoki, R, Petrovic, K, Reynolds, CA, Sargurupremraj, M, Scholz, M, Smith, JA, Smith, AV, Terzikhan, N, Thalamuthu, A, Trompet, S, Van Der Lee, SJ, Ware, EB, Windham, BG, Wright, MJ, Yang, J, Yu, J, Ames, D, Amin, N, Amouyel, P, Andreassen, OA, Armstrong, NJ, Assareh, AA, Attia, JR, Attix, D, Avramopoulos, D, Bennett, DA, Böhmer, AC, Boyle, PA, Brodaty, H
Publikováno v:
Davies, G; Lam, M; Harris, SE; Trampush, JW; Luciano, M; Hill, WD; et al.(2018). Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications, 9(1). doi: 10.1038/s41467-018-04362-x. UCLA: Retrieved from: http://www.escholarship.org/uc/item/13g1w2rc
© 2018 The Author(s). General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::6015d06c9226adc75509fd8642b513a0
http://www.escholarship.org/uc/item/13g1w2rc
http://www.escholarship.org/uc/item/13g1w2rc
Autor:
Häkkinen K; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio FI-70240, Finland.; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki FI-00014, Finland., Kiander W; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland., Kidron H; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland., Lähteenvuo M; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio FI-70240, Finland., Urpa L; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki FI-00014, Finland., Lintunen J; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio FI-70240, Finland., Vellonen KS; School of Pharmacy, University of Eastern Finland, Kuopio FI-70211, Finland., Auriola S; School of Pharmacy, University of Eastern Finland, Kuopio FI-70211, Finland., Holm M; Mental Health Team, Finnish Institute for Health and Welfare, Helsinki FI-00271, Finland., Lahdensuo K; Mehiläinen Ltd, Helsinki FI-00260, Finland., Kampman O; Faculty of Medicine and Health Technology, Tampere University, Tampere FI-33100, Finland.; Department of Psychiatry, Pirkanmaa Hospital District, Tampere FI-33521, Finland.; Department of Clinical Sciences (Psychiatry), Faculty of Medicine, Umeå University, Umeå SE-90187, Sweden.; Department of Psychiatry, University Hospital of Umeå, Umeå SE-90187, Sweden.; Department of Clinical Medicine (Psychiatry), Faculty of Medicine, University of Turku, Turku FI-20014, Finland.; Department of Psychiatry, The Wellbeing Services County of Ostrobothnia, Vaasa FI-65101, Finland., Isometsä E; Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Helsinki FI-00014, Finland., Kieseppä T; Mental Health Team, Finnish Institute for Health and Welfare, Helsinki FI-00271, Finland.; Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Helsinki FI-00014, Finland., Lönnqvist J; Mental Health Team, Finnish Institute for Health and Welfare, Helsinki FI-00271, Finland.; Department of Psychiatry, University of Helsinki, Helsinki FI-00014, Finland., Suvisaari J; Mental Health Team, Finnish Institute for Health and Welfare, Helsinki FI-00271, Finland., Hietala J; Department of Psychiatry, University of Turku and Turku University Hospital, Turku FI-20700, Finland., Tiihonen J; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio FI-70240, Finland.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm SE-17177, Sweden.; Center for Psychiatry Research, Stockholm City Council, Stockholm SE-11364, Sweden.; Neuroscience Center, University of Helsinki, Helsinki FI-00014, Finland., Palotie A; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki FI-00014, Finland.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston MA-02114, United States., Ahola-Olli AV; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki FI-00014, Finland.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.; Department of Internal Medicine, Satasairaala Hospital, Pori FI-28500, Finland., Niemi M; Department of Clinical Pharmacology, University of Helsinki, Helsinki FI-00014, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki FI-00014, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki FI-00029, Finland.
Publikováno v:
Molecular pharmaceutics [Mol Pharm] 2023 Mar 06; Vol. 20 (3), pp. 1500-1508. Date of Electronic Publication: 2023 Feb 13.
Autor:
Häkkinen K; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, FI-70240, Kuopio, Finland. katja.hakkinen@niuva.fi.; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland. katja.hakkinen@niuva.fi., Kiiski JI; Department of Clinical Pharmacology, University of Helsinki, FI-00014, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, FI-00014, Helsinki, Finland., Lähteenvuo M; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, FI-70240, Kuopio, Finland.; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland., Jukuri T; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Department of Psychiatry, University of Oulu, FI-90014, Oulu, Finland., Suokas K; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Tampere University, FI-33014, Tampere, Finland., Niemi-Pynttäri J; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Social Services and Health Care Sector, City of Helsinki, FI-00099, Helsinki, Finland., Kieseppä T; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; University of Helsinki, Helsinki University Hospital, Psychiatry, FI-00029, Helsinki, Finland.; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland., Männynsalo T; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Social Services and Health Care Sector, City of Helsinki, FI-00099, Helsinki, Finland., Wegelius A; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; University of Helsinki, Helsinki University Hospital, Psychiatry, FI-00029, Helsinki, Finland.; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland., Haaki W; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Department of Psychiatry, University of Turku and Turku University Hospital, FI-20521, Turku, Finland., Lahdensuo K; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Mehiläinen, FI-00260, Helsinki, Finland., Kajanne R; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland., Kaunisto MA; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland., Tuulio-Henriksson A; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, FI-00014, Helsinki, Finland., Kampman O; Tampere University, FI-33014, Tampere, Finland.; Department of Psychiatry, Pirkanmaa Hospital District, FI-33521, Tampere, Finland., Hietala J; Department of Psychiatry, University of Turku and Turku University Hospital, FI-20521, Turku, Finland., Veijola J; Department of Psychiatry, University of Oulu, FI-90014, Oulu, Finland.; Department of Psychiatry, Oulu University Hospital, FI-90220, Oulu, Finland., Lönnqvist J; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland.; Department of Psychiatry, University of Helsinki, FI-00014, Helsinki, Finland., Isometsä E; University of Helsinki, Helsinki University Hospital, Psychiatry, FI-00029, Helsinki, Finland., Paunio T; University of Helsinki, Helsinki University Hospital, Psychiatry, FI-00029, Helsinki, Finland.; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland.; Department of Psychiatry, University of Helsinki, FI-00014, Helsinki, Finland., Suvisaari J; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland., Kalso E; Pain Clinic, Department of Anesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, FI-00290, Helsinki, Finland., Niemi M; Department of Clinical Pharmacology, University of Helsinki, FI-00014, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, FI-00014, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, FI-00029, Helsinki, Finland., Tiihonen J; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, FI-70240, Kuopio, Finland.; Department of Clinical Neuroscience, Karolinska Institutet, SE-17177, Stockholm, Sweden.; Center for Psychiatry Research, Stockholm City Council, SE-11364, Stockholm, Sweden., Daly M; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Stanley Center for Psychiatric Research, The Broad Institute of MIT (Massachusetts Institute of Technology) and Harvard, MA-02142, Cambridge, MA, USA.; Analytical and Translational Genetics Unit, Massachusetts General Hospital, MA-02114, Boston, MA, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Stanley Center for Psychiatric Research, The Broad Institute of MIT (Massachusetts Institute of Technology) and Harvard, MA-02142, Cambridge, MA, USA.; Analytical and Translational Genetics Unit, Massachusetts General Hospital, MA-02114, Boston, MA, USA., Ahola-Olli AV; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014, Helsinki, Finland.; Stanley Center for Psychiatric Research, The Broad Institute of MIT (Massachusetts Institute of Technology) and Harvard, MA-02142, Cambridge, MA, USA.; Analytical and Translational Genetics Unit, Massachusetts General Hospital, MA-02114, Boston, MA, USA.
Publikováno v:
The pharmacogenomics journal [Pharmacogenomics J] 2022 May; Vol. 22 (3), pp. 166-172. Date of Electronic Publication: 2022 Feb 23.
Autor:
Kalaoja M; Computational Medicine, Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland., Corbin LJ; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Tan VY; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Ahola-Olli AV; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland., Havulinna AS; Finnish Institute for Health and Welfare, Helsinki, Finland., Santalahti K; Medicity Research Laboratory and Institute of Biomedicine, University of Turku, Turku, Finland., Pitkänen N; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitoharju E; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Ripatti S; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Palotie A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Perola M; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.; Finnish Institute for Health and Welfare, Helsinki, Finland., Viikari JS; Department of Medicine, University of Turku, Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland., Jalkanen S; Medicity Research Laboratory and Institute of Biomedicine, University of Turku, Turku, Finland., Maksimow M; Medicity Research Laboratory and Institute of Biomedicine, University of Turku, Turku, Finland., Salomaa V; Finnish Institute for Health and Welfare, Helsinki, Finland., Salmi M; Medicity Research Laboratory and Institute of Biomedicine, University of Turku, Turku, Finland., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku, Turku University Hospital, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, University of Turku, Turku, Finland., Kettunen J; Computational Medicine, Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Finnish Institute for Health and Welfare, Helsinki, Finland., Timpson NJ; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Publikováno v:
Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2021 Feb; Vol. 29 (2), pp. 428-437.
Autor:
Nath AP; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, United Kingdom; Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address: artika.nath@baker.edu.au., Ritchie SC; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, United Kingdom., Grinberg NF; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Cambridge CB2 0AW, United Kingdom., Tang HH; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia., Huang QQ; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia; Department of Clinical Pathology, University of Melbourne, Parkville, Victoria 3010, Australia., Teo SM; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, United Kingdom., Ahola-Olli AV; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki 00014, Finland., Würtz P; Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki 00014, Finland; Nightingale Health Ltd., Helsinki 00300, Finland., Havulinna AS; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki 00014, Finland; National Institute of Health and Welfare, Helsinki 00271, Finland., Santalahti K; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, Turku 20520, Finland., Pitkänen N; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland., Kähönen M; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland; Department of Clinical Physiology, Tampere University Hospital, Tampere 33521, Finland., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland., Raitoharju E; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland; Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland., Sarin AP; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki 00014, Finland; National Institute of Health and Welfare, Helsinki 00271, Finland., Ripatti S; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki 00014, Finland; Department of Public Health, University of Helsinki, Helsinki 00014, Finland; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Palotie A; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki 00014, Finland; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Perola M; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki 00014, Finland; National Institute of Health and Welfare, Helsinki 00271, Finland., Viikari JS; Department of Medicine, University of Turku, Turku 20520, Finland; Division of Medicine, Turku University Hospital, Turku 20520, Finland., Jalkanen S; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, Turku 20520, Finland., Maksimow M; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, Turku 20520, Finland., Salmi M; Medicity Research Laboratory and Institute of Biomedicine, University of Turku, Turku 20520, Finland., Wallace C; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Cambridge CB2 0AW, United Kingdom; MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 0SR, United Kingdom., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland; The Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20520, Finland., Salomaa V; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, Turku 20520, Finland., Abraham G; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, United Kingdom; Department of Clinical Pathology, University of Melbourne, Parkville, Victoria 3010, Australia., Kettunen J; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, Turku 20520, Finland; Computational Medicine, Centre for Life Course Health Research, University of Oulu, Oulu 90014, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio 70211, Finland; Biocenter Oulu, University of Oulu, Oulu 90014, Finland., Inouye M; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, United Kingdom; Department of Clinical Pathology, University of Melbourne, Parkville, Victoria 3010, Australia; The Alan Turing Institute, London, United Kingdom. Electronic address: mi336@medschl.cam.ac.uk.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2019 Dec 05; Vol. 105 (6), pp. 1076-1090. Date of Electronic Publication: 2019 Oct 31.
Autor:
Ahola-Olli AV; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Kiinamyllynkatu 10, 20520, Turku, Finland. avahol@utu.fi.; Department of Internal Medicine, Satakunta Central Hospital, Sairaalantie 3, 28500, Pori, Finland. avahol@utu.fi.; Institute for Molecular Medicine (FIMM), University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland. avahol@utu.fi., Mustelin L; Institute for Molecular Medicine (FIMM), University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland.; Nightingale Health Ltd, Mannerheimintie 164a, 00300, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Kalimeri M; Nightingale Health Ltd, Mannerheimintie 164a, 00300, Helsinki, Finland., Kettunen J; Centre for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland.; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Jokelainen J; Centre for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland., Auvinen J; Centre for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland.; Oulunkaari Primary Health Care Unit, Ii, Finland., Puukka K; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Nordlab Oulu, Oulu University Hospital, Oulu, Finland.; Department of Clinical Chemistry, University of Oulu, Oulu, Finland., Havulinna AS; Institute for Molecular Medicine (FIMM), University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Kähönen M; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Juonala M; Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland., Keinänen-Kiukaanniemi S; Centre for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland.; Healthcare and Social Services of Selanne, Pyhasalmi, Finland.; Diabetes Unit, Healthcare Services of City of Oulu, Oulu, Finland., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Perola M; Institute for Molecular Medicine (FIMM), University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Järvelin MR; Centre for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland.; Department of Epidemiology and Biostatistics, Medical Research Council-Public Health England Centre for Environment and Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University, London, UK., Ala-Korpela M; Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland.; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK.; Systems Epidemiology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital, Monash University, Melbourne, Victoria, Australia., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Kiinamyllynkatu 10, 20520, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Würtz P; Nightingale Health Ltd, Mannerheimintie 164a, 00300, Helsinki, Finland. peter.wurtz@nightingalehealth.com.; Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland. peter.wurtz@nightingalehealth.com.
Publikováno v:
Diabetologia [Diabetologia] 2019 Dec; Vol. 62 (12), pp. 2298-2309. Date of Electronic Publication: 2019 Oct 04.
Autor:
Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Lam M; Institute of Mental Health, Singapore, 539747, Singapore., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Medical Genetics Section, Centre for Genomic & Experimental Medicine, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Trampush JW; BrainWorkup, LLC, Los Angeles, 90033, CA, USA.; Department of Psychiatry and Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, 90033, CA, USA., Luciano M; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Hill WD; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK., Ritchie SJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Marioni RE; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Medical Genetics Section, Centre for Genomic & Experimental Medicine, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Fawns-Ritchie C; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Okely JA; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Ahola-Olli AV; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland.; Department of Internal Medicine, Satakunta Central Hospital, Pori, 28100, Finland., Barnes CLK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Bertram L; Max Planck Institute for Molecular Genetics, Berlin, 14195, Germany., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, 98101, Washington, USA., Burdick KE; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Mental Illness Research, Education, and Clinical Center (VISN 3), James J. Peters VA Medical Center, Bronx, 10468, NY, USA.; Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, 02115, MA, USA., Christoforou A; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., DeRosse P; Institute of Mental Health, Singapore, 539747, Singapore.; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA., Djurovic S; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Department of Medical Genetics, Oslo University Hospital, University of Bergen, Oslo, 0424, Norway., Espeseth T; Department of Psychology, University of Oslo, Oslo, 0373, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, 0315, Norway., Giakoumaki S; Department of Psychology, University of Crete, Crete, GR-74100, Greece., Giddaluru S; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., Gustavson DE; Department of Psychiatry, University of California, San Diego, 92093, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, 92093, CA, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Hofer E; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria.; Institute of Medical Informatics Statistics and Documentation, Medical University of Graz, Graz, 8036, Austria., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Neurology, Erasmus University Medical Center, Rotterdam, xxxxxx, The Netherlands., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Knowles E; Department of Psychiatry, Yale University School of Medicine, New Haven, 06511, CT, USA., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, 00014, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, 00014, Finland., Leber M; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, D-50937, Germany., Li S; Department of Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia., Melle I; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Department of Psychology, University of Oslo, Oslo, 0373, Norway., Morris D; Neuroimaging, Cognition & Genomics (NICOG) Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, H91 TK33, Ireland., Oldmeadow C; Medical Research Institute and Faculty of Health, University of Newcastle, New South Wa0les, 2308, Australia., Palviainen T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Payton A; Centre for EpidemiologyDivision of Population Health, Health Services Research & Primary Care, The University of Manchester, Manchester, M13 9PL, UK., Pazoki R; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK., Petrovic K; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria., Reynolds CA; Department of Psychology, University of California Riverside, Riverside, 92521, CA, USA., Sargurupremraj M; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, 04107, Germany.; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, 04107, Germany., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Smith AV; Icelandic Heart Association, Kopavogur, IS-201, Iceland.; University of Iceland, Reykjavik, 101, Iceland., Terzikhan N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium., Thalamuthu A; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia., Trompet S; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, 2333, The Netherlands., van der Lee SJ; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Ware EB; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Windham BG; Department of Medicine, Division of Geriatrics, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Wright MJ; Queensland Brain Institute, University of Queensland, Brisbane, 4072, Australia.; Centre for Advanced Imaging, University of Queensland, Brisbane, 4072, Australia., Yang J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, 60612, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, 60612, IL, USA., Yu J; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA., Ames D; National Ageing Research Institute, Royal Melbourne Hospital, Victoria, 3052, Australia.; Academic Unit for Psychiatry of Old Age, University of Melbourne, St George's Hospital, Kew, 3010, Australia., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Amouyel P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-LabEx DISTALZ, F-59000, Lille, France., Andreassen OA; Department of Psychology, University of Oslo, Oslo, 0373, Norway.; Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, 0372, Norway., Armstrong NJ; Mathematics and Statistics, Murdoch University, Perth, 6150, Australia., Assareh AA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia., Attia JR; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New South Wales, 2305, Australia., Attix D; Department of NeurologyBryan Alzheimer's Disease Research Center, and Center for Genomic and Computational Biology, Duke University Medical Center, Durham, 27708, NC, USA.; Psychiatry and Behavioral Sciences, Division of Medical Psychology, and Department of Neurology, Duke University Medical Center, Durham, 27708, NC, USA., Avramopoulos D; Department of Psychiatry, Johns Hopkins University School of Medicine, MD, Baltimore, 21287, USA.; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, 21287, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, 60612, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, 60612, IL, USA., Böhmer AC; Institute of Human Genetics, University of Bonn, Bonn, 53113, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, 53113, Germany., Boyle PA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, 60612, IL, USA.; Departments of Behavioral Sciences, Rush University Medical Center, Chicago, 60612, IL, USA., Brodaty H; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Dementia Centre for Research Collaboration, University of New South Wales, Sydney, 2031, NSW, Australia., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Cannon TD; Department of Psychology, Yale University, New Haven, 06520, CT, USA., Cirulli ET; Human Longevity Inc, Durham, 27709, NC, USA., Congdon E; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Conley ED; 23andMe, Inc., Mountain View, 94041, CA, USA., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Cox SR; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Dale AM; Department of Psychiatry, University of California, San Diego, 92093, CA, USA.; Department of Cognitive Science, University of California, San Diego, La Jolla, 92093, CA, USA.; Department of Neurosciences, University of California, San Diego, La Jolla, 92093, CA, USA.; Department of Radiology, University of California, San Diego, La Jolla, 92093, CA, USA., Dehghan A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment, School of Public Health, Imperial College London, London, W2 1PG, UK., Dick D; Department of Psychology, Virginia Commonwealth University, Richmond, 23284, VA, USA., Dickinson D; Clinical and Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institute of Health, Bethesda, 20892, MD, USA., Eriksson JG; National Institute for Health and Welfare, Helsinki, FI-00271, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, 00290, Finland.; Helsinki University Central Hospital, Unit of General Practice, Helsinki, FI-00029, Finland.; Folkhälsan Research Centre, Helsinki, 2018, Finland., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; National Institute for Health and Welfare, Helsinki, FI-00271, Finland., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, G12 8QQ, United Kingdom., Freimer NA; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Gao H; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK., Giegling I; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Gillespie NA; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, 23298, VA, USA., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia., Gottesman RF; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, 21205, MD, USA., Griswold ME; Department of Data Science, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Gudnason V; Icelandic Heart Association, Kopavogur, IS-201, Iceland.; University of Iceland, Reykjavik, 101, Iceland., Harris TB; Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., Hartmann AM; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Hatzimanolis A; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens, 11528, Greece.; University Mental Health Research Institute, Athens, GR-156 01, Greece.; Neurobiology Research Institute, Theodor-Theohari Cozzika Foundation, Athens, 11521, Greece., Heiss G; Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27599, NC, USA., Holliday EG; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New South Wales, 2305, Australia., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center, Tampere, FI-33014, Finland.; Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33521, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Karlsson I; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Kleineidam L; Department of Psychiatry Medical Faculty, University of Cologne, Cologne, 50923, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, 53127, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, 53127, Germany.; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, 53127, Germany., Knopman DS; Department of Neurology, Mayo Clinic, Rochester, 55905, MN, USA., Kochan NA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, 2031, Australia., Konte B; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Kwok JB; Brain and Mind Centre-The University of Sydney, Camperdown, NSW, 2050, Australia.; School of Medical Sciences, University of New South Wales, Sydney, 2052, Australia., Le Hellard S; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., Lee T; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, 2031, Australia., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Li SC; Max Planck Institute for Human Development, Berlin, 14195, Germany.; Technische Universität Dresden, Dresden, 01187, Germany., Lill CM; Genetic and Molecular Epidemiology Group, Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics & Cardiogenetics, University of Lübeck, Lübeck, Germany., Liu T; Max Planck Institute for Molecular Genetics, Berlin, 14195, Germany.; Max Planck Institute for Human Development, Berlin, 14195, Germany., Koini M; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria., London E; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Longstreth WT Jr; Department of Neurology, School of Medicine, University of Washington, Seattle, 98195-6465, WA, USA.; Department of Epidemiology, University of Washington, Seattle, 98195, WA, USA., Lopez OL; Department of Neurology and Psychiatry, University of Pittsburgh, Pittsburgh, 15213, PA, USA., Loukola A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Luck T; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, 04107, Germany.; Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, 04103, Germany., Lundervold AJ; Department of Biological and Medical Psychology, University of Bergen, Bergen, 5009, Norway.; K. G. Jebsen Center for Neuropsychiatry, University of Bergen, Bergen, N-5009, Norway., Lundquist A; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, SE-901 87, Sweden.; Department of Statistics, USBE Umeå University, S-907 97, Umeå, Sweden., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, 4072, Australia., Murray AD; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, AB25 2ZD, UK., Need AC; Division of Brain Sciences, Department of Medicine, Imperial College, London, SW7 2AZ, UK., Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, 2333, The Netherlands., Nyberg L; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, SE-901 87, Sweden.; Department of Radiation Sciences, Umeå University, Umeå, SE-901 87, Sweden.; Department of Integrative Medical Biology, Umeå University, Umeå, SE-901 87, Sweden., Ollier W; Centre for Integrated Genomic Medical Research, Institute of Population Health, University of Manchester, Manchester, M13 9PT, UK., Papenberg G; Max Planck Institute for Human Development, Berlin, 14195, Germany.; Karolinska Institutet, Aging Research Center, Stockholm University, Stockholm, SE-113 30, Sweden., Pattie A; Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Polasek O; Gen-Info LLC, Zagreb, 10000, Croatia.; Faculty of Medicine, University of Split, Split, 21000, Croatia., Poldrack RA; Department of Psychology, Stanford University, Palo Alto, 94305-2130, CA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, 98101, Washington, USA.; Deparment of Health Services, University of Washington, Seattle, 98195-7660, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, 98101, WA, USA., Reppermund S; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, 2052, Australia., Riedel-Heller SG; Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, 04103, Germany., Rose RJ; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, 47405-7007, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90509, CA, USA., Roussos P; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Mental Illness Research, Education, and Clinical Center (VISN 2), James J. Peters VA Medical Center, Bronx, 10468, NY, USA., Rovio SP; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland., Saba Y; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, 8036, Austria., Sabb FW; Robert and Beverly Lewis Center for Neuroimaging, University of Oregon, Eugene, 97403, OR, USA., Sachdev PS; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, 2031, Australia., Satizabal CL; Department of Neurology, Boston University School of Medicine, Boston, 02118, MA, USA.; The National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, 01702-5827, MA, USA., Schmid M; Department of Medical Biometry, Informatics and Epidemiology, University Hospital, Bonn, D-53012, Germany., Scott RJ; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New South Wales, 2305, Australia., Scult MA; Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, 27708-0086, NC, USA., Simino J; Department of Data Science, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Slagboom PE; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, 2333, The Netherlands., Smyrnis N; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens, 11528, Greece.; University Mental Health Research Institute, Athens, GR-156 01, Greece., Soumaré A; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France., Stefanis NC; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens, 11528, Greece.; University Mental Health Research Institute, Athens, GR-156 01, Greece.; Neurobiology Research Institute, Theodor-Theohari Cozzika Foundation, Athens, 11521, Greece., Stott DJ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom., Straub RE; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, 21205, MD, USA., Sundet K; Department of Psychology, University of Oslo, Oslo, 0373, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, 0315, Norway., Taylor AM; Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90509, CA, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment, School of Public Health, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Tzourio C; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France.; Department of Public Health, University Hospital of Bordeaux, Bordeaux, 33076, France., Uitterlinden A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, 3015, The Netherlands., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Voineskos AN; Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, M5T 1L8, Canada., Kaprio J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland.; National Institute for Health and Welfare, Helsinki, FI-00271, Finland.; Department of Public Health, University of Helsinki, Helsinki, 00014, Finland., Wagner M; German Center for Neurodegenerative Diseases (DZNE), Bonn, 53127, Germany.; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, 53127, Germany., Wagner H; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, 53127, Germany., Weinhold L; Department of Medical Biometry, Informatics and Epidemiology, University Hospital, Bonn, D-53012, Germany., Wen KH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Widen E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Adams HHH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Radiology, Erasmus MC, Rotterdam, 3015, The Netherlands., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, 21287, USA., Bilder RM; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Bitsios P; Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, GR-71003, Greece., Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, 77030-3411, TX, USA., Chiba-Falek O; Department of NeurologyBryan Alzheimer's Disease Research Center, and Center for Genomic and Computational Biology, Duke University Medical Center, Durham, 27708, NC, USA., Corvin A; Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, DO2 AY89, Ireland., De Jager PL; Center for Translational and Systems Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, 10032, NY, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, MA, USA., Debette S; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France.; Department of Neurology, University Hospital of Bordeaux, Bordeaux, 33000, France., Donohoe G; Neuroimaging, Cognition & Genomics (NICOG) Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, H91 TK33, Ireland., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment, School of Public Health, Imperial College London, London, W2 1PG, UK., Fitzpatrick AL; Department of Epidemiology, University of Washington, Seattle, 98195, WA, USA.; Department of Global Health, University of Washington, Seattle, 98104, WA, USA., Gill M; Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, DO2 AY89, Ireland., Glahn DC; Department of Psychiatry, Yale University School of Medicine, New Haven, 06511, CT, USA., Hägg S; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Hansell NK; Queensland Brain Institute, University of Queensland, Brisbane, 4072, Australia., Hariri AR; Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, 27708-0086, NC, USA., Ikram MK; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Neurology, Erasmus University Medical Center, Rotterdam, xxxxxx, The Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, 2333, The Netherlands., Vuoksimaa E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland.; Department of Public Health, University of Helsinki, Helsinki, 00014, Finland., Keller MC; Institute for Behavioral Genetics, University of Colorado, Boulder, 80309, CO, USA., Kremen WS; Department of Psychiatry, University of California, San Diego, 92093, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, 92093, CA, USA., Launer L; Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., Lindenberger U; Max Planck Institute for Human Development, Berlin, 14195, Germany., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, CB10 1SA, UK.; Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, 00014, Finland., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Pendleton N; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Manchester Academic Health Science Centre, and Manchester Medical School, Institute of Brain, Behaviour, and Mental Health, University of Manchester, Manchester, M13 9PL, UK., Porteous DJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Medical Genetics Section, Centre for Genomic & Experimental Medicine, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, 00014, Finland., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20520, Finland., Ramirez A; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, D-50937, Germany.; Institute of Human Genetics, University of Bonn, Bonn, 53113, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, 53127, Germany., Reinvang I; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, 0315, Norway., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Dan Rujescu; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Schmidt R; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria., Schmidt H; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, 8036, Austria., Schofield PW; School of Medicine and Public Health, University of Newcastle, New South Wales, 2308, Australia., Schofield PR; Neuroscience Research Australia, Sydney, 2031, Australia.; Faculty of Medicine, University of New South Wales, Sydney, 2052, Australia., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Steen VM; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., Trollor JN; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, 2052, Australia., Turner ST; Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Villringer A; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, 04103, Germany.; Day Clinic for Cognitive Neurology, University Hospital Leipzig, Leipzig, 04103, Germany., Weinberger DR; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, 21205, MD, USA., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Wilson JF; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Malhotra A; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA.; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, 11004, NY, USA.; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, 11549, NY, USA., McIntosh AM; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Division of Psychiatry, University of Edinburgh, Edinburgh, EH10 5HF, UK., Gale CR; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, SO16 6YD, UK., Seshadri S; Robert and Beverly Lewis Center for Neuroimaging, University of Oregon, Eugene, 97403, OR, USA.; Department of Neurology, Boston University School of Medicine, Boston, 02118, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, 78229, TX, USA., Mosley TH Jr; Department of Medicine, Division of Geriatrics, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Bressler J; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Lencz T; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA.; Division of Psychiatry, University of Edinburgh, Edinburgh, EH10 5HF, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK. i.deary@ed.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2019 May 01; Vol. 10 (1), pp. 2068. Date of Electronic Publication: 2019 May 01.
Autor:
Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Lam M; Institute of Mental Health, Singapore, 539747, Singapore., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Medical Genetics Section, Centre for Genomic & Experimental Medicine, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Trampush JW; BrainWorkup, LLC, Los Angeles, 90033, CA, USA.; Department of Psychiatry and Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, 90033, CA, USA., Luciano M; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Hill WD; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK., Ritchie SJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Marioni RE; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Medical Genetics Section, Centre for Genomic & Experimental Medicine, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Fawns-Ritchie C; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Okely JA; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Ahola-Olli AV; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland.; Department of Internal Medicine, Satakunta Central Hospital, Pori, 28100, Finland., Barnes CLK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Bertram L; Max Planck Institute for Molecular Genetics, Berlin, 14195, Germany., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, 98101, Washington, USA., Burdick KE; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Mental Illness Research, Education, and Clinical Center (VISN 3), James J. Peters VA Medical Center, Bronx, 10468, NY, USA.; Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, 02115, MA, USA., Christoforou A; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., DeRosse P; Institute of Mental Health, Singapore, 539747, Singapore.; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA., Djurovic S; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Department of Medical Genetics, Oslo University Hospital, University of Bergen, Oslo, 0424, Norway., Espeseth T; Department of Psychology, University of Oslo, Oslo, 0373, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, 0315, Norway., Giakoumaki S; Department of Psychology, University of Crete, Crete, GR-74100, Greece., Giddaluru S; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., Gustavson DE; Department of Psychiatry, University of California, San Diego, 92093, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, 92093, CA, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Hofer E; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria.; Institute of Medical Informatics Statistics and Documentation, Medical University of Graz, Graz, 8036, Austria., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Neurology, Erasmus University Medical Center, Rotterdam, xxxxxx, The Netherlands., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Knowles E; Department of Psychiatry, Yale University School of Medicine, New Haven, 06511, CT, USA., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, 00014, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, 00014, Finland., Leber M; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, D-50937, Germany., Li S; Department of Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia., Melle I; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Department of Psychology, University of Oslo, Oslo, 0373, Norway., Morris D; Neuroimaging, Cognition & Genomics (NICOG) Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, H91 TK33, Ireland., Oldmeadow C; Medical Research Institute and Faculty of Health, University of Newcastle, New South Wa0les, 2308, Australia., Palviainen T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Payton A; Centre for EpidemiologyDivision of Population Health, Health Services Research & Primary Care, The University of Manchester, Manchester, M13 9PL, UK., Pazoki R; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK., Petrovic K; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria., Reynolds CA; Department of Psychology, University of California Riverside, Riverside, 92521, CA, USA., Sargurupremraj M; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, 04107, Germany.; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, 04107, Germany., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Smith AV; Icelandic Heart Association, Kopavogur, IS-201, Iceland.; University of Iceland, Reykjavik, 101, Iceland., Terzikhan N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium., Thalamuthu A; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia., Trompet S; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, 2333, The Netherlands., van der Lee SJ; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Ware EB; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Windham BG; Department of Medicine, Division of Geriatrics, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Wright MJ; Queensland Brain Institute, University of Queensland, Brisbane, 4072, Australia.; Centre for Advanced Imaging, University of Queensland, Brisbane, 4072, Australia., Yang J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, 60612, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, 60612, IL, USA., Yu J; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA., Ames D; National Ageing Research Institute, Royal Melbourne Hospital, Victoria, 3052, Australia.; Academic Unit for Psychiatry of Old Age, University of Melbourne, St George's Hospital, Kew, 3010, Australia., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Amouyel P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-LabEx DISTALZ, F-59000, Lille, France., Andreassen OA; Department of Psychology, University of Oslo, Oslo, 0373, Norway.; Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, 0372, Norway., Armstrong NJ; Mathematics and Statistics, Murdoch University, Perth, 6150, Australia., Assareh AA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia., Attia JR; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New South Wales, 2305, Australia., Attix D; Department of NeurologyBryan Alzheimer's Disease Research Center, and Center for Genomic and Computational Biology, Duke University Medical Center, Durham, 27708, NC, USA.; Psychiatry and Behavioral Sciences, Division of Medical Psychology, and Department of Neurology, Duke University Medical Center, Durham, 27708, NC, USA., Avramopoulos D; Department of Psychiatry, Johns Hopkins University School of Medicine, MD, Baltimore, 21287, USA.; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, 21287, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, 60612, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, 60612, IL, USA., Böhmer AC; Institute of Human Genetics, University of Bonn, Bonn, 53113, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, 53113, Germany., Boyle PA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, 60612, IL, USA.; Departments of Behavioral Sciences, Rush University Medical Center, Chicago, 60612, IL, USA., Brodaty H; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Dementia Centre for Research Collaboration, University of New South Wales, Sydney, 2031, NSW, Australia., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Cannon TD; Department of Psychology, Yale University, New Haven, 06520, CT, USA., Cirulli ET; Human Longevity Inc, Durham, 27709, NC, USA., Congdon E; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Conley ED; 23andMe, Inc., Mountain View, 94041, CA, USA., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Cox SR; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Dale AM; Department of Psychiatry, University of California, San Diego, 92093, CA, USA.; Department of Cognitive Science, University of California, San Diego, La Jolla, 92093, CA, USA.; Department of Neurosciences, University of California, San Diego, La Jolla, 92093, CA, USA.; Department of Radiology, University of California, San Diego, La Jolla, 92093, CA, USA., Dehghan A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment, School of Public Health, Imperial College London, London, W2 1PG, UK., Dick D; Department of Psychology, Virginia Commonwealth University, Richmond, 23284, VA, USA., Dickinson D; Clinical and Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institute of Health, Bethesda, 20892, MD, USA., Eriksson JG; National Institute for Health and Welfare, Helsinki, FI-00271, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, 00290, Finland.; Helsinki University Central Hospital, Unit of General Practice, Helsinki, FI-00029, Finland.; Folkhälsan Research Centre, Helsinki, 2018, Finland., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; National Institute for Health and Welfare, Helsinki, FI-00271, Finland., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, G12 8QQ, United Kingdom., Freimer NA; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Gao H; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK., Giegling I; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Gillespie NA; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, 23298, VA, USA., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia., Gottesman RF; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, 21205, MD, USA., Griswold ME; Department of Data Science, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Gudnason V; Icelandic Heart Association, Kopavogur, IS-201, Iceland.; University of Iceland, Reykjavik, 101, Iceland., Harris TB; Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., Hartmann AM; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Hatzimanolis A; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens, 11528, Greece.; University Mental Health Research Institute, Athens, GR-156 01, Greece.; Neurobiology Research Institute, Theodor-Theohari Cozzika Foundation, Athens, 11521, Greece., Heiss G; Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27599, NC, USA., Holliday EG; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New South Wales, 2305, Australia., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center, Tampere, FI-33014, Finland.; Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33521, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Karlsson I; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Kleineidam L; Department of Psychiatry Medical Faculty, University of Cologne, Cologne, 50923, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, 53127, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, 53127, Germany.; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, 53127, Germany., Knopman DS; Department of Neurology, Mayo Clinic, Rochester, 55905, MN, USA., Kochan NA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, 2031, Australia., Konte B; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Kwok JB; Brain and Mind Centre-The University of Sydney, Camperdown, NSW, 2050, Australia.; School of Medical Sciences, University of New South Wales, Sydney, 2052, Australia., Le Hellard S; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., Lee T; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, 2031, Australia., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Li SC; Max Planck Institute for Human Development, Berlin, 14195, Germany.; Technische Universität Dresden, Dresden, 01187, Germany., Lill CM; Genetic and Molecular Epidemiology Group, Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics & Cardiogenetics, University of Lübeck, Lübeck, Germany., Liu T; Max Planck Institute for Molecular Genetics, Berlin, 14195, Germany.; Max Planck Institute for Human Development, Berlin, 14195, Germany., Koini M; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria., London E; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Longstreth WT Jr; Department of Neurology, School of Medicine, University of Washington, Seattle, 98195-6465, WA, USA.; Department of Epidemiology, University of Washington, Seattle, 98195, WA, USA., Lopez OL; Department of Neurology and Psychiatry, University of Pittsburgh, Pittsburgh, 15213, PA, USA., Loukola A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Luck T; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, 04107, Germany.; Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, 04103, Germany., Lundervold AJ; Department of Biological and Medical Psychology, University of Bergen, Bergen, 5009, Norway.; K. G. Jebsen Center for Neuropsychiatry, University of Bergen, Bergen, N-5009, Norway., Lundquist A; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, SE-901 87, Sweden.; Department of Statistics, USBE Umeå University, S-907 97, Umeå, Sweden., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, 4072, Australia., Murray AD; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, AB25 2ZD, UK., Need AC; Division of Brain Sciences, Department of Medicine, Imperial College, London, SW7 2AZ, UK., Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, 2333, The Netherlands., Nyberg L; Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, SE-901 87, Sweden.; Department of Radiation Sciences, Umeå University, Umeå, SE-901 87, Sweden.; Department of Integrative Medical Biology, Umeå University, Umeå, SE-901 87, Sweden., Ollier W; Centre for Integrated Genomic Medical Research, Institute of Population Health, University of Manchester, Manchester, M13 9PT, UK., Papenberg G; Max Planck Institute for Human Development, Berlin, 14195, Germany.; Karolinska Institutet, Aging Research Center, Stockholm University, Stockholm, SE-113 30, Sweden., Pattie A; Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Polasek O; Gen-Info LLC, Zagreb, 10000, Croatia.; Faculty of Medicine, University of Split, Split, 21000, Croatia., Poldrack RA; Department of Psychology, Stanford University, Palo Alto, 94305-2130, CA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, 98101, Washington, USA.; Deparment of Health Services, University of Washington, Seattle, 98195-7660, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, 98101, WA, USA., Reppermund S; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, 2052, Australia., Riedel-Heller SG; Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, 04103, Germany., Rose RJ; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, 47405-7007, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90509, CA, USA., Roussos P; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Mental Illness Research, Education, and Clinical Center (VISN 2), James J. Peters VA Medical Center, Bronx, 10468, NY, USA., Rovio SP; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland., Saba Y; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, 8036, Austria., Sabb FW; Robert and Beverly Lewis Center for Neuroimaging, University of Oregon, Eugene, 97403, OR, USA., Sachdev PS; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, 2031, Australia., Satizabal CL; Department of Neurology, Boston University School of Medicine, Boston, 02118, MA, USA.; The National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, 01702-5827, MA, USA., Schmid M; Department of Medical Biometry, Informatics and Epidemiology, University Hospital, Bonn, D-53012, Germany., Scott RJ; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New South Wales, 2305, Australia., Scult MA; Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, 27708-0086, NC, USA., Simino J; Department of Data Science, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Slagboom PE; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, 2333, The Netherlands., Smyrnis N; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens, 11528, Greece.; University Mental Health Research Institute, Athens, GR-156 01, Greece., Soumaré A; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France., Stefanis NC; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens, 11528, Greece.; University Mental Health Research Institute, Athens, GR-156 01, Greece.; Neurobiology Research Institute, Theodor-Theohari Cozzika Foundation, Athens, 11521, Greece., Stott DJ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom., Straub RE; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, 21205, MD, USA., Sundet K; Department of Psychology, University of Oslo, Oslo, 0373, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, 0315, Norway., Taylor AM; Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, 90509, CA, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment, School of Public Health, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Tzourio C; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France.; Department of Public Health, University Hospital of Bordeaux, Bordeaux, 33076, France., Uitterlinden A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, 3015, The Netherlands., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Voineskos AN; Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, M5T 1L8, Canada., Kaprio J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland.; National Institute for Health and Welfare, Helsinki, FI-00271, Finland.; Department of Public Health, University of Helsinki, Helsinki, 00014, Finland., Wagner M; German Center for Neurodegenerative Diseases (DZNE), Bonn, 53127, Germany.; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, 53127, Germany., Wagner H; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, 53127, Germany., Weinhold L; Department of Medical Biometry, Informatics and Epidemiology, University Hospital, Bonn, D-53012, Germany., Wen KH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Widen E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Adams HHH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Radiology, Erasmus MC, Rotterdam, 3015, The Netherlands., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, 21287, USA., Bilder RM; UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, 90024, CA, USA., Bitsios P; Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, GR-71003, Greece., Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, 77030-3411, TX, USA., Chiba-Falek O; Department of NeurologyBryan Alzheimer's Disease Research Center, and Center for Genomic and Computational Biology, Duke University Medical Center, Durham, 27708, NC, USA., Corvin A; Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, DO2 AY89, Ireland., De Jager PL; Center for Translational and Systems Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, 10032, NY, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, MA, USA., Debette S; University of Bordeaux, Bordeaux Population Health Research Center, INSERM UMR 1219, F-33000, Bordeaux, France.; Department of Neurology, University Hospital of Bordeaux, Bordeaux, 33000, France., Donohoe G; Neuroimaging, Cognition & Genomics (NICOG) Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, H91 TK33, Ireland., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment, School of Public Health, Imperial College London, London, W2 1PG, UK., Fitzpatrick AL; Department of Epidemiology, University of Washington, Seattle, 98195, WA, USA.; Department of Global Health, University of Washington, Seattle, 98104, WA, USA., Gill M; Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, DO2 AY89, Ireland., Glahn DC; Department of Psychiatry, Yale University School of Medicine, New Haven, 06511, CT, USA., Hägg S; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Hansell NK; Queensland Brain Institute, University of Queensland, Brisbane, 4072, Australia., Hariri AR; Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, 27708-0086, NC, USA., Ikram MK; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands.; Department of Neurology, Erasmus University Medical Center, Rotterdam, xxxxxx, The Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, 2333, The Netherlands., Vuoksimaa E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland.; Department of Public Health, University of Helsinki, Helsinki, 00014, Finland., Keller MC; Institute for Behavioral Genetics, University of Colorado, Boulder, 80309, CO, USA., Kremen WS; Department of Psychiatry, University of California, San Diego, 92093, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, 92093, CA, USA., Launer L; Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., Lindenberger U; Max Planck Institute for Human Development, Berlin, 14195, Germany., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, CB10 1SA, UK.; Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, 00014, Finland., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE-171 77, Sweden., Pendleton N; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Manchester Academic Health Science Centre, and Manchester Medical School, Institute of Brain, Behaviour, and Mental Health, University of Manchester, Manchester, M13 9PL, UK., Porteous DJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Medical Genetics Section, Centre for Genomic & Experimental Medicine, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, 00014, Finland., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20520, Finland., Ramirez A; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, D-50937, Germany.; Institute of Human Genetics, University of Bonn, Bonn, 53113, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, 53127, Germany., Reinvang I; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, 0315, Norway., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Dan Rujescu; Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, 06108, Germany., Schmidt R; Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, 8036, Austria., Schmidt H; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, 8036, Austria., Schofield PW; School of Medicine and Public Health, University of Newcastle, New South Wales, 2308, Australia., Schofield PR; Neuroscience Research Australia, Sydney, 2031, Australia.; Faculty of Medicine, University of New South Wales, Sydney, 2052, Australia., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Steen VM; NORMENT, K.G. Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, 5021, Norway.; Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5020, Norway., Trollor JN; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2031, Australia.; Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, 2052, Australia., Turner ST; Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015, The Netherlands., Villringer A; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, 04103, Germany.; Day Clinic for Cognitive Neurology, University Hospital Leipzig, Leipzig, 04103, Germany., Weinberger DR; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, 21205, MD, USA., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Wilson JF; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Malhotra A; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA.; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, 11004, NY, USA.; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, 11549, NY, USA., McIntosh AM; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Division of Psychiatry, University of Edinburgh, Edinburgh, EH10 5HF, UK., Gale CR; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, SO16 6YD, UK., Seshadri S; Robert and Beverly Lewis Center for Neuroimaging, University of Oregon, Eugene, 97403, OR, USA.; Department of Neurology, Boston University School of Medicine, Boston, 02118, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, 78229, TX, USA., Mosley TH Jr; Department of Medicine, Division of Geriatrics, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Bressler J; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Lencz T; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, 11030, NY, USA.; Division of Psychiatry, University of Edinburgh, Edinburgh, EH10 5HF, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK. i.deary@ed.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2018 May 29; Vol. 9 (1), pp. 2098. Date of Electronic Publication: 2018 May 29.
Autor:
Ahola-Olli AV; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland. Electronic address: avahol@utu.fi., Würtz P; Computational Medicine, Center for Life Course Health Research, University of Oulu, 90014 Oulu, Finland., Havulinna AS; National Institute of Health and Welfare, 00271 Helsinki, Finland., Aalto K; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, 20520 Turku, Finland., Pitkänen N; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland., Lehtimäki T; The Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, 33014 Tampere, Finland., Kähönen M; The Department of Clinical Physiology, Tampere University Hospital, 33521 Tampere, Finland., Lyytikäinen LP; The Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, 33014 Tampere, Finland., Raitoharju E; The Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, 33014 Tampere, Finland., Seppälä I; The Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, 33014 Tampere, Finland., Sarin AP; National Institute of Health and Welfare, 00271 Helsinki, Finland; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, 00014 Helsinki, Finland., Ripatti S; National Institute of Health and Welfare, 00271 Helsinki, Finland; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, 00014 Helsinki, Finland; The Department of Public Health, University of Helsinki, 00271 Helsinki, Finland., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, 00014 Helsinki, Finland; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA., Perola M; National Institute of Health and Welfare, 00271 Helsinki, Finland; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, 00014 Helsinki, Finland., Viikari JS; The Department of Medicine, University of Turku, 20520 Turku, Finland; Division of Medicine, Turku University Hospital, 20520 Turku, Finland., Jalkanen S; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, 20520 Turku, Finland., Maksimow M; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, 20520 Turku, Finland., Salomaa V; National Institute of Health and Welfare, 00271 Helsinki, Finland., Salmi M; Medicity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku, 20520 Turku, Finland., Kettunen J; Computational Medicine, Center for Life Course Health Research, University of Oulu, 90014 Oulu, Finland; National Institute of Health and Welfare, 00271 Helsinki, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, 70211 Kuopio, Finland; Biocenter Oulu, University of Oulu, 90014 Oulu, Finland., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland; Biocenter Oulu, University of Oulu, 90014 Oulu, Finland; The Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, 20520 Turku, Finland.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2017 Jan 05; Vol. 100 (1), pp. 40-50. Date of Electronic Publication: 2016 Dec 15.
Autor:
Ahola-Olli AV; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Pitkänen N; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Kettunen J; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Oikonen MK; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Mikkilä V; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Lehtimäki T; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Kähönen M; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Pahkala K; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Niinikoski H; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Kangas AJ; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Soininen P; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Ala-Korpela M; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Viikari JS; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Rönnemaa T; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Simell O; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR)., Raitakari OT; From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR).
Publikováno v:
The American journal of clinical nutrition [Am J Clin Nutr] 2014 Dec; Vol. 100 (6), pp. 1569-77. Date of Electronic Publication: 2014 Oct 08.